Patents by Inventor Bruce P. England

Bruce P. England has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides and compounds that bind to the IL-5 receptor
    Patent number: 5683983
    Abstract: Described are peptides and peptide mimetics that bind to and the IL-5 receptor. Such peptides and peptide mimetics are useful in methods for treating disorders that involve improper production of or response to IL-5 and or the production and accumulation of eosinophils, such as asthma, as well as in diagnostic methods employing labeled peptides and peptide mimetics.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 4, 1997
    Assignee: Glaxo Group Limited
    Inventors: Ronald W. Barrett, Bruce P. England, Peter J. Schatz, Derek Sloan, Min-Jia Chen
  • Peptides and compounds that bind to the IL-5 receptor
    Patent number: 5677280
    Abstract: Described are peptides and peptide mimetics that bind to and the IL-5 receptor. Such peptides and peptide mimetics are useful in methods for treating disorders that involve improper production of or response to IL-5 and or the production and accumulation of eosinophils, such as asthma, as well as in diagnostic methods employing labeled peptides and peptide mimetics.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 14, 1997
    Assignee: Glaxo Group Limited
    Inventors: Ronald W. Barrett, Bruce P. England, Peter J. Schatz, Derek Sloan, Min-Jia Chen
  • Peptides and compounds that bind to the IL-5 receptor
    Patent number: 5668110
    Abstract: Described are peptides and peptide mimetics that bind to and the IL-5 receptor. Such peptides and peptide mimetics are useful in methods for treating disorders that involve improper production of or response to IL-5 and or the production and accumulation of eosinophils, such as asthma, as well as in diagnostic methods employing labeled peptides and peptide mimetics.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 16, 1997
    Assignee: Affymax Technologies N.V.
    Inventors: Ronald W. Barrett, Bruce P. England, Peter J. Schatz, Derek Sloan, Min-Jia Chen
  • Peptides and compounds that bind to the IL-5 receptor
    Patent number: 5654276
    Abstract: Described are peptides and peptide mimetics that bind to and the IL-receptor. Such peptides and peptide mimetics are useful in methods for treating disorders that involve improper production of or response to IL-5 and or the production and accumulation of eosinophils, such as asthma, as well as in diagnostic methods employing labeled peptides and peptide mimetics.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 5, 1997
    Assignee: Affymax Technologies N.V.
    Inventors: Ronald W. Barrett, Bruce P. England, Peter J. Schatz, Derek Sloan, Min-Jia Chen
  • Nucleic acid encoding the D.sub.2 /Ml chimeric receptor
    Patent number: 5264565
    Abstract: Chimeric G-protein linked receptors are constructed which retain ligand binding specificity yet gain the ability to elevate intracellular free calcium as a result of agonist binding. This easily assayed function is provided by the insertion of or replacement with sequences substantially homologous to the i3 loop of a second G-protein-linked receptor. Such receptors are employed, for example, in methods of screening for compounds capable of acting as agonists or antagonists of G-protein-linked receptors.
    Type: Grant
    Filed: January 22, 1991
    Date of Patent: November 23, 1993
    Assignee: Affymax Technologies, N.V.
    Inventors: Bruce P. England, Ronald W. Barrett