Patents by Inventor Bruce P. Gunn

Bruce P. Gunn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Furan and pyrrole containing lipoxygenase inhibiting compounds
    Patent number: 5112848
    Abstract: Substituted furan and pyrrole compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase.
    Type: Grant
    Filed: April 19, 1990
    Date of Patent: May 12, 1992
    Assignee: Abbott Laboratories
    Inventors: Dee W. Brooks, Bruce P. Gunn, James H. Holms, James B. Summers
  • Substituted 1,4,5,6-tetrahydro-2H-pyridazin-3-one and -3-thione compounds having lipoxygenase inhibitory activity
    Patent number: 5086052
    Abstract: Pyridazinone, triazinone and oxapyridazinone compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase.
    Type: Grant
    Filed: June 28, 1990
    Date of Patent: February 4, 1992
    Assignee: Abbott Laboratories
    Inventors: Dee W. Brooks, George W. Carter, Anwer Basha, Bruce P. Gunn, Richard D. Dyer
  • Triazinone lipoxygenase compounds
    Patent number: 4970210
    Abstract: Pyridazinone, triazinone and oxapyridazinone compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase.
    Type: Grant
    Filed: June 28, 1988
    Date of Patent: November 13, 1990
    Assignee: Abbott Laboratories
    Inventors: Dee W. Brooks, Anwer Basha, Bruce P. Gunn, Pramila A. Bhatia
  • Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds
    Patent number: 4873259
    Abstract: Compounds of the formula: ##STR1## wherein R.sub.1 is (1) hydrogen, (2) C.sub.1 to C.sub.4 alkyl, (3) C.sub.2 to C.sub.4 alkenyl, or (4) NR.sub.2 R.sub.3, wherein R.sub.2 and R.sub.3 are independently selected from (1) hydrogen, (2) C.sub.1 to C.sub.4 alkyl and (3) hydroxyl, but R.sub.2 and R.sub.3 are not simultaneously hydroxyl;wherein X is oxygen, sulfur, SO.sub.2, or NR.sub.4, wherein R.sub.4 is (1) hydrogen, (2) C.sub.1 to C.sub.6 alkyl, (3) C.sub.1 to C.sub.6 alkoyl, (4) aroyl, or (5) alkylsulfonyl;A is selected from C.sub.1 to C.sub.6 alkylene and C.sub.2 to C.sub.6 alkenylene;n is 1-5;Y is selected independently at each occurrence from (1) hydrogen, (2) halogen, (3) hydroxy, (4) cyano, (5) halosubstituted alkyl, (6) C.sub.1 to C.sub.12 alkyl, (7) C.sub.2 to C.sub.12 alkenyl, (8) C.sub.1 to C.sub.12 alkoxy, (9) C.sub.3 to C.sub.8 cycloalkyl, (10) C.sub.1 -C.sub.8 thioalkyl, (11) aryl, (12) aryloxy, (13) aroyl, (14) C.sub.1 to C.sub.12 arylalkyl, (15) C.sub.2 to C.sub.12 arylalkenyl, (16) C.sub.1 to C.
    Type: Grant
    Filed: January 11, 1988
    Date of Patent: October 10, 1989
    Assignee: Abbott Laboratories
    Inventors: James B. Summers, Jr., Bruce P. Gunn, Dee W. Brooks
  • Lipoxygenase inhibiting compounds
    Patent number: 4761403
    Abstract: Hydroxy quinol-1-one and quinol-2-one based compounds found to be potent inhibitors of 5-, 12-, and 15-lipoxygenase enzymes.
    Type: Grant
    Filed: April 9, 1986
    Date of Patent: August 2, 1988
    Assignee: Abbott Laboratories
    Inventors: Bruce P. Gunn, James B. Summers, Jr.