Patents by Inventor Bruce Phelps

Bruce Phelps has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210318298
    Abstract: Disclosed is a covalently-linked multilayered three-dimensional matrix comprising capture molecules, linkers and spacers (referred to as a Molecular Net) for specific and sensitive analyte capture from a sample. Also disclosed herein is a Molecular Net comprising covalently-linked multilayered three-dimensional matrix comprising more than one type of capture molecule and more than one type of linker and may comprise one or more spacer for specific and sensitive capture of more than one type of analyte from a sample. A Molecular Net may comprise a pseudorandom nature. Use of various capture molecules, linkers and spacers in a Molecular Net may confer unique binding properties to a Molecular Net. Porosity, binding affinity, size exclusion abilities, filtration abilities, concentration abilities and signal amplification abilities of a Molecular Net may be varied and depend on the nature of components used in its fabrication.
    Type: Application
    Filed: December 21, 2020
    Publication date: October 14, 2021
    Applicant: Sienna Cancer Diagnostics Inc.
    Inventors: Emily A. STEIN, Bruce PHELPS, Robert PLACE, Dina UZRI
  • Patent number: 10900962
    Abstract: Disclosed is a covalently-linked multilayered three-dimensional matrix comprising capture molecules, linkers and spacers (referred to as a Molecular Net) for specific and sensitive analyte capture from a sample. Also disclosed herein is a Molecular Net comprising covalently-linked multilayered three-dimensional matrix comprising more than one type of capture molecule and more than one type of linker and may comprise one or more spacer for specific and sensitive capture of more than one type of analyte from a sample. A Molecular Net may comprise a pseudorandom nature. Use of various capture molecules, linkers and spacers in a Molecular Net may confer unique binding properties to a Molecular Net. Porosity, binding affinity, size exclusion abilities, filtration abilities, concentration abilities and signal amplification abilities of a Molecular Net may be varied and depend on the nature of components used in its fabrication.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: January 26, 2021
    Assignee: Sienna Cancer Diagnostics Inc.
    Inventors: Emily A. Stein, Bruce Phelps, Robert Place, Dina Uzri
  • Publication number: 20180143188
    Abstract: Disclosed is a covalently-linked multilayered three-dimensional matrix comprising capture molecules, linkers and spacers (referred to as a Molecular Net) for specific and sensitive analyte capture from a sample. Also disclosed herein is a Molecular Net comprising covalently-linked multilayered three-dimensional matrix comprising more than one type of capture molecule and more than one type of linker and may comprise one or more spacer for specific and sensitive capture of more than one type of analyte from a sample. A Molecular Net may comprise a pseudorandom nature. Use of various capture molecules, linkers and spacers in a Molecular Net may confer unique binding properties to a Molecular Net. Porosity, binding affinity, size exclusion abilities, filtration abilities, concentration abilities and signal amplification abilities of a Molecular Net may be varied and depend on the nature of components used in its fabrication.
    Type: Application
    Filed: July 6, 2017
    Publication date: May 24, 2018
    Applicant: Sevident, Inc.
    Inventors: Emily A. STEIN, Bruce PHELPS, Robert PLACE, Dina UZRI
  • Patent number: 9733242
    Abstract: Disclosed is a covalently-linked multilayered three-dimensional matrix comprising capture molecules, linkers and spacers (referred to as a Molecular Net) for specific and sensitive analyte capture from a sample. Also disclosed herein is a Molecular Net comprising covalently-linked multilayered three-dimensional matrix comprising more than one type of capture molecule and more than one type of linker and may comprise one or more spacer for specific and sensitive capture of more than one type of analyte from a sample. A Molecular Net may comprise a pseudorandom nature. Use of various capture molecules, linkers and spacers in a Molecular Net may confer unique binding properties to a Molecular Net. Porosity, binding affinity, size exclusion abilities, filtration abilities, concentration abilities and signal amplification abilities of a Molecular Net may be varied and depend on the nature of components used in its fabrication.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: August 15, 2017
    Assignee: Sevident, Inc.
    Inventors: Emily Stein, Bruce Phelps, Robert Place, Dina Uzri
  • Publication number: 20150376704
    Abstract: The disclosed methods, assays and kits identify biomarkers, particularly miRNA and/or protein biomarkers, for assessing the cardiovascular health of a human. In certain embodiments, methods, assays and kits, circulating miRNA and/or protein biomarkers are identified for assessing the cardiovascular health of a human.
    Type: Application
    Filed: July 1, 2015
    Publication date: December 31, 2015
    Applicant: CLEVELAND HEARTLAB, INC.
    Inventors: Doug Harrington, Evangelos Hytopoulos, Bruce Phelps
  • Publication number: 20140315759
    Abstract: Disclosed is a covalently-linked multilayered three-dimensional matrix comprising capture molecules, linkers and spacers (referred to as a Molecular Net) for specific and sensitive analyte capture from a sample. Also disclosed herein is a Molecular Net comprising covalently-linked multilayered three-dimensional matrix comprising more than one type of capture molecule and more than one type of linker and may comprise one or more spacer for specific and sensitive capture of more than one type of analyte from a sample. A Molecular Net may comprise a pseudorandom nature. Use of various capture molecules, linkers and spacers in a Molecular Net may confer unique binding properties to a Molecular Net. Porosity, binding affinity, size exclusion abilities, filtration abilities, concentration abilities and signal amplification abilities of a Molecular Net may be varied and depend on the nature of components used in its fabrication.
    Type: Application
    Filed: March 14, 2014
    Publication date: October 23, 2014
    Applicant: Sevident, Inc.
    Inventors: Emily STEIN, Bruce PHELPS, Robert PLACE, Dina UZRI
  • Publication number: 20110144914
    Abstract: The disclosed methods, assays and kits identify biomarkers, particularly miRNA and/or protein biomarkers, for assessing the cardiovascular health of a human. In certain embodiments, methods, assays and kits, circulating miRNA and/or protein biomarkers are identified for assessing the cardiovascular health of a human.
    Type: Application
    Filed: December 9, 2010
    Publication date: June 16, 2011
    Inventors: Doug Harrington, Evangelos Hytopoulos, Bruce Phelps
  • Patent number: 7795037
    Abstract: Methods for using semiconductor nanocrystals for determining fluid movement, fluid dilution and fluid removal are described. Methods for using semiconductor nanocrystals for monitoring and quantifying the amounts of solid materials dissolved in a liquid are also described.
    Type: Grant
    Filed: June 6, 2008
    Date of Patent: September 14, 2010
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Willy Lagwinski, Charles Harrington, Bruce Phelps
  • Publication number: 20090065171
    Abstract: A cooling system (100) for a motor vehicle includes a snorkel (102) positioned on the vehicle for collecting air while the vehicle is moving. An air duct (104) is coupled with the snorkel (102) on a first end and has an exhaust at a second end. A heat exchanger (106) is coupled with a component such as a transmission (108) of the vehicle and positioned within the duct (104) for cooling the component (108) with the air passing through the duct (104).
    Type: Application
    Filed: May 5, 2005
    Publication date: March 12, 2009
    Inventors: Robert Harry McPherson, Bruce Phelps Hollenbeck
  • Patent number: 7497201
    Abstract: A control system is provided for controlling the fueling system (402) of a combustion engine. The control system includes a sensing arrangement for measuring a plurality of engine and vehicle conditions (404, 406, 408, 410, 412) in real time. The control system also includes a fuel map that defines engine fueling parameters corresponding to engine operating conditions. The control system also includes a control module (102) that determines engine load from the sensed conditions, and controls the fueling parameters of the fueling system for optimized fuel consumption by selecting fueling parameters from the fuel map based on current engine load.
    Type: Grant
    Filed: November 17, 2004
    Date of Patent: March 3, 2009
    Assignee: Mack Trucks, Inc.
    Inventor: Bruce Phelps Hollenbeck
  • Patent number: 7472946
    Abstract: An improved truck architecture includes a truck frame, a cab coupled with the truck frame, and a hood. The cab has a front end and a rear end. The front end of the cab is positioned over the truck engine such that a portion of the engine is positioned beneath the cab. A device is provided for lifting and tilting the cab rearward relative to the engine to provide access to the engine. The hood is coupled with the truck frame and covers the remaining portion of the engine not covered by the cab.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: January 6, 2009
    Assignee: Mack Trucks, Inc.
    Inventors: Bruce Phelps Hollenbeck, Donald Ashley Hoey, Ruben Perfetti, Jeffery Robert Cotner, David Peter Onopa, Brian David Balicki
  • Patent number: 7463966
    Abstract: A power storage device is provided for a motor vehicle. An engine control unit (ECU) is configured to receive measurements of one or more engine and/or vehicle conditions and to determine an amount of unused engine power based upon the measurements and upon a nominal power rating of the engine when the engine is operated below the nominal power rating. The value of the amount of unused engine power is stored in memory as stored power.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: December 9, 2008
    Assignee: Mack Trucks, Inc.
    Inventor: Bruce Phelps Hollenbeck
  • Publication number: 20080243353
    Abstract: A power storage device is provided for a motor vehicle. An engine control unit (ECU) is configured to receive measurements of one or more engine and/or vehicle conditions and to determine an amount of unused engine power based upon the measurements and upon a nominal power rating of the engine when the engine is operated below the nominal power rating. The value of the amount of unused engine power is stored in memory as stored power.
    Type: Application
    Filed: January 24, 2005
    Publication date: October 2, 2008
    Applicant: Mack Trucks, Inc.
    Inventor: Bruce Phelps Hollenbeck
  • Publication number: 20070192228
    Abstract: In at least one aspect, the invention comprises a method comprising the steps of: identifying a first portfolio of securities as corresponding, at a specified time, to an index; calculating, for the first portfolio, a first set of performance values comprising one or more of: book yield, book income, and book return; calculating, for a second portfolio of securities, a second set of performance values corresponding to the first set of performance values; and comparing the second set of performance values to the first set of performance values to obtain a performance measure for the second portfolio.
    Type: Application
    Filed: September 28, 2006
    Publication date: August 16, 2007
    Applicant: Lehman Brothers Inc.
    Inventors: Bruce Phelps, Lev Dynkin, Jordan Mann, Yang Chen
  • Publication number: 20050048519
    Abstract: A device for in-line blood screening and testing using biochips is disclosed. The screening methods include nucleic acid amplification techniques and antibody/antigen assays to detect target molecules and agents indicative of infectious diseases or metabolic diseases.
    Type: Application
    Filed: December 12, 2003
    Publication date: March 3, 2005
    Inventors: David Chien, Bruce Phelps
  • Patent number: 6830537
    Abstract: A vehicle, such as, e.g., a diesel-powered truck, has a transmission control system that, e.g., improves fuel efficiency and/or consumption. In some embodiments, the vehicle includes: an engine that powers said vehicle; a transmission to change ratios between engine speed and wheel speed; and at least one control unit configured to shift the transmission in a plurality of lower gears substantially against the governed speed of the engine and to shift the transmission in a plurality of higher gears substantially against the peak torque speed of the engine.
    Type: Grant
    Filed: August 29, 2003
    Date of Patent: December 14, 2004
    Assignee: Mack Trucks, Inc.
    Inventor: Bruce Phelps Hollenbeck