Patents by Inventor Bruce Phelps
Bruce Phelps has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210318298Abstract: Disclosed is a covalently-linked multilayered three-dimensional matrix comprising capture molecules, linkers and spacers (referred to as a Molecular Net) for specific and sensitive analyte capture from a sample. Also disclosed herein is a Molecular Net comprising covalently-linked multilayered three-dimensional matrix comprising more than one type of capture molecule and more than one type of linker and may comprise one or more spacer for specific and sensitive capture of more than one type of analyte from a sample. A Molecular Net may comprise a pseudorandom nature. Use of various capture molecules, linkers and spacers in a Molecular Net may confer unique binding properties to a Molecular Net. Porosity, binding affinity, size exclusion abilities, filtration abilities, concentration abilities and signal amplification abilities of a Molecular Net may be varied and depend on the nature of components used in its fabrication.Type: ApplicationFiled: December 21, 2020Publication date: October 14, 2021Applicant: Sienna Cancer Diagnostics Inc.Inventors: Emily A. STEIN, Bruce PHELPS, Robert PLACE, Dina UZRI
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Patent number: 10900962Abstract: Disclosed is a covalently-linked multilayered three-dimensional matrix comprising capture molecules, linkers and spacers (referred to as a Molecular Net) for specific and sensitive analyte capture from a sample. Also disclosed herein is a Molecular Net comprising covalently-linked multilayered three-dimensional matrix comprising more than one type of capture molecule and more than one type of linker and may comprise one or more spacer for specific and sensitive capture of more than one type of analyte from a sample. A Molecular Net may comprise a pseudorandom nature. Use of various capture molecules, linkers and spacers in a Molecular Net may confer unique binding properties to a Molecular Net. Porosity, binding affinity, size exclusion abilities, filtration abilities, concentration abilities and signal amplification abilities of a Molecular Net may be varied and depend on the nature of components used in its fabrication.Type: GrantFiled: July 6, 2017Date of Patent: January 26, 2021Assignee: Sienna Cancer Diagnostics Inc.Inventors: Emily A. Stein, Bruce Phelps, Robert Place, Dina Uzri
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Publication number: 20180143188Abstract: Disclosed is a covalently-linked multilayered three-dimensional matrix comprising capture molecules, linkers and spacers (referred to as a Molecular Net) for specific and sensitive analyte capture from a sample. Also disclosed herein is a Molecular Net comprising covalently-linked multilayered three-dimensional matrix comprising more than one type of capture molecule and more than one type of linker and may comprise one or more spacer for specific and sensitive capture of more than one type of analyte from a sample. A Molecular Net may comprise a pseudorandom nature. Use of various capture molecules, linkers and spacers in a Molecular Net may confer unique binding properties to a Molecular Net. Porosity, binding affinity, size exclusion abilities, filtration abilities, concentration abilities and signal amplification abilities of a Molecular Net may be varied and depend on the nature of components used in its fabrication.Type: ApplicationFiled: July 6, 2017Publication date: May 24, 2018Applicant: Sevident, Inc.Inventors: Emily A. STEIN, Bruce PHELPS, Robert PLACE, Dina UZRI
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Patent number: 9733242Abstract: Disclosed is a covalently-linked multilayered three-dimensional matrix comprising capture molecules, linkers and spacers (referred to as a Molecular Net) for specific and sensitive analyte capture from a sample. Also disclosed herein is a Molecular Net comprising covalently-linked multilayered three-dimensional matrix comprising more than one type of capture molecule and more than one type of linker and may comprise one or more spacer for specific and sensitive capture of more than one type of analyte from a sample. A Molecular Net may comprise a pseudorandom nature. Use of various capture molecules, linkers and spacers in a Molecular Net may confer unique binding properties to a Molecular Net. Porosity, binding affinity, size exclusion abilities, filtration abilities, concentration abilities and signal amplification abilities of a Molecular Net may be varied and depend on the nature of components used in its fabrication.Type: GrantFiled: March 14, 2014Date of Patent: August 15, 2017Assignee: Sevident, Inc.Inventors: Emily Stein, Bruce Phelps, Robert Place, Dina Uzri
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Publication number: 20150376704Abstract: The disclosed methods, assays and kits identify biomarkers, particularly miRNA and/or protein biomarkers, for assessing the cardiovascular health of a human. In certain embodiments, methods, assays and kits, circulating miRNA and/or protein biomarkers are identified for assessing the cardiovascular health of a human.Type: ApplicationFiled: July 1, 2015Publication date: December 31, 2015Applicant: CLEVELAND HEARTLAB, INC.Inventors: Doug Harrington, Evangelos Hytopoulos, Bruce Phelps
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Publication number: 20140315759Abstract: Disclosed is a covalently-linked multilayered three-dimensional matrix comprising capture molecules, linkers and spacers (referred to as a Molecular Net) for specific and sensitive analyte capture from a sample. Also disclosed herein is a Molecular Net comprising covalently-linked multilayered three-dimensional matrix comprising more than one type of capture molecule and more than one type of linker and may comprise one or more spacer for specific and sensitive capture of more than one type of analyte from a sample. A Molecular Net may comprise a pseudorandom nature. Use of various capture molecules, linkers and spacers in a Molecular Net may confer unique binding properties to a Molecular Net. Porosity, binding affinity, size exclusion abilities, filtration abilities, concentration abilities and signal amplification abilities of a Molecular Net may be varied and depend on the nature of components used in its fabrication.Type: ApplicationFiled: March 14, 2014Publication date: October 23, 2014Applicant: Sevident, Inc.Inventors: Emily STEIN, Bruce PHELPS, Robert PLACE, Dina UZRI
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Publication number: 20110144914Abstract: The disclosed methods, assays and kits identify biomarkers, particularly miRNA and/or protein biomarkers, for assessing the cardiovascular health of a human. In certain embodiments, methods, assays and kits, circulating miRNA and/or protein biomarkers are identified for assessing the cardiovascular health of a human.Type: ApplicationFiled: December 9, 2010Publication date: June 16, 2011Inventors: Doug Harrington, Evangelos Hytopoulos, Bruce Phelps
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Patent number: 7795037Abstract: Methods for using semiconductor nanocrystals for determining fluid movement, fluid dilution and fluid removal are described. Methods for using semiconductor nanocrystals for monitoring and quantifying the amounts of solid materials dissolved in a liquid are also described.Type: GrantFiled: June 6, 2008Date of Patent: September 14, 2010Assignee: Novartis Vaccines and Diagnostics, Inc.Inventors: Willy Lagwinski, Charles Harrington, Bruce Phelps
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Publication number: 20090065171Abstract: A cooling system (100) for a motor vehicle includes a snorkel (102) positioned on the vehicle for collecting air while the vehicle is moving. An air duct (104) is coupled with the snorkel (102) on a first end and has an exhaust at a second end. A heat exchanger (106) is coupled with a component such as a transmission (108) of the vehicle and positioned within the duct (104) for cooling the component (108) with the air passing through the duct (104).Type: ApplicationFiled: May 5, 2005Publication date: March 12, 2009Inventors: Robert Harry McPherson, Bruce Phelps Hollenbeck
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Patent number: 7497201Abstract: A control system is provided for controlling the fueling system (402) of a combustion engine. The control system includes a sensing arrangement for measuring a plurality of engine and vehicle conditions (404, 406, 408, 410, 412) in real time. The control system also includes a fuel map that defines engine fueling parameters corresponding to engine operating conditions. The control system also includes a control module (102) that determines engine load from the sensed conditions, and controls the fueling parameters of the fueling system for optimized fuel consumption by selecting fueling parameters from the fuel map based on current engine load.Type: GrantFiled: November 17, 2004Date of Patent: March 3, 2009Assignee: Mack Trucks, Inc.Inventor: Bruce Phelps Hollenbeck
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Patent number: 7472946Abstract: An improved truck architecture includes a truck frame, a cab coupled with the truck frame, and a hood. The cab has a front end and a rear end. The front end of the cab is positioned over the truck engine such that a portion of the engine is positioned beneath the cab. A device is provided for lifting and tilting the cab rearward relative to the engine to provide access to the engine. The hood is coupled with the truck frame and covers the remaining portion of the engine not covered by the cab.Type: GrantFiled: January 16, 2007Date of Patent: January 6, 2009Assignee: Mack Trucks, Inc.Inventors: Bruce Phelps Hollenbeck, Donald Ashley Hoey, Ruben Perfetti, Jeffery Robert Cotner, David Peter Onopa, Brian David Balicki
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Patent number: 7463966Abstract: A power storage device is provided for a motor vehicle. An engine control unit (ECU) is configured to receive measurements of one or more engine and/or vehicle conditions and to determine an amount of unused engine power based upon the measurements and upon a nominal power rating of the engine when the engine is operated below the nominal power rating. The value of the amount of unused engine power is stored in memory as stored power.Type: GrantFiled: January 24, 2005Date of Patent: December 9, 2008Assignee: Mack Trucks, Inc.Inventor: Bruce Phelps Hollenbeck
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Publication number: 20080243353Abstract: A power storage device is provided for a motor vehicle. An engine control unit (ECU) is configured to receive measurements of one or more engine and/or vehicle conditions and to determine an amount of unused engine power based upon the measurements and upon a nominal power rating of the engine when the engine is operated below the nominal power rating. The value of the amount of unused engine power is stored in memory as stored power.Type: ApplicationFiled: January 24, 2005Publication date: October 2, 2008Applicant: Mack Trucks, Inc.Inventor: Bruce Phelps Hollenbeck
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Publication number: 20070192228Abstract: In at least one aspect, the invention comprises a method comprising the steps of: identifying a first portfolio of securities as corresponding, at a specified time, to an index; calculating, for the first portfolio, a first set of performance values comprising one or more of: book yield, book income, and book return; calculating, for a second portfolio of securities, a second set of performance values corresponding to the first set of performance values; and comparing the second set of performance values to the first set of performance values to obtain a performance measure for the second portfolio.Type: ApplicationFiled: September 28, 2006Publication date: August 16, 2007Applicant: Lehman Brothers Inc.Inventors: Bruce Phelps, Lev Dynkin, Jordan Mann, Yang Chen
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Publication number: 20050048519Abstract: A device for in-line blood screening and testing using biochips is disclosed. The screening methods include nucleic acid amplification techniques and antibody/antigen assays to detect target molecules and agents indicative of infectious diseases or metabolic diseases.Type: ApplicationFiled: December 12, 2003Publication date: March 3, 2005Inventors: David Chien, Bruce Phelps
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Patent number: 6830537Abstract: A vehicle, such as, e.g., a diesel-powered truck, has a transmission control system that, e.g., improves fuel efficiency and/or consumption. In some embodiments, the vehicle includes: an engine that powers said vehicle; a transmission to change ratios between engine speed and wheel speed; and at least one control unit configured to shift the transmission in a plurality of lower gears substantially against the governed speed of the engine and to shift the transmission in a plurality of higher gears substantially against the peak torque speed of the engine.Type: GrantFiled: August 29, 2003Date of Patent: December 14, 2004Assignee: Mack Trucks, Inc.Inventor: Bruce Phelps Hollenbeck