Abstract: Disposable handheld devices for manually cleaning nostrils and/or other body orifices are disclosed herein. A device configured in accordance with one embodiment of the invention includes a shaft having a first end portion spaced apart from a second end portion to define a first exterior surface portion therebetween with at least one ridge portion extending outwardly therefrom. The device can further include a first tip portion positioned toward the first end portion of the shaft and a second tip portion positioned toward the second end portion of the shaft. The first tip portion can include a second ridge portion extending outwardly from a second exterior surface portion. The second tip portion can include a third ridge portion extending outwardly from a third exterior surface portion.