Patents by Inventor Bruce R. Blazer

Bruce R. Blazer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Drug-resistant immune cells and methods of use thereof
    Patent number: 12343397
    Abstract: The present disclosure provides modified cells including pluripotent stem cells, hematopoietic precursor cells, and hematopoietic cells (e.g., modified Tregs) that are steroid and/or calcineurin inhibitor-resistant. The present disclosure provides methods for generating steroid and/or calcineurin inhibitor-resistant modified cells including pluripotent stem cells, hematopoietic precursor cells, and hematopoietic cells. Also provided herein are compositions and methods of treatment.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: July 1, 2025
    Assignee: Regents of the University of Minnesota
    Inventors: Mark J. Osborn, Keli Hippen, Bruce R. Blazer
  • Drug-Resistant Immune Cells and Methods of Use Thereof
    Publication number: 20210213062
    Abstract: The present disclosure provides modified cells including pluripotent stem cells, hematopoietic precursor cells, and hematopoietic cells (e.g., modified Tregs) that are steroid and/or calcineurin inhibitor-resistant. The present disclosure provides methods for generating steroid and/or calcineurin inhibitor-resistant modified cells including pluripotent stem cells, hematopoietic precursor cells, and hematopoietic cells. Also provided herein are compositions and methods of treatment.
    Type: Application
    Filed: May 16, 2019
    Publication date: July 15, 2021
    Inventors: Mark J. Osborn, Keli Hippen, Bruce R. Blazer