Patents by Inventor Bruce S. Ross

Bruce S. Ross has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VARIEGATED POLYMER-BASED MATERIALS
    Publication number: 20240131768
    Abstract: Polymer-based sheet materials having a variegated appearance are provided. The polymer-based-sheet material may have a core with one or more caps. The cap(s) may be on a first primary surface, a second primary surface, and/or sides. The variegation may be within and/or on the cap and/or the core. Methods, systems, articles, and materials effective for a polymer-based sheet material having a variegated appearance are provided.
    Type: Application
    Filed: December 12, 2023
    Publication date: April 25, 2024
    Inventors: Bruce Edward STANHOPE, Jeffrey S. Ross, Cesar Samano
  • NUCLEOSIDE PHOSPHORAMIDATES
    Publication number: 20160354400
    Abstract: Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.
    Type: Application
    Filed: February 5, 2016
    Publication date: December 8, 2016
    Inventors: Bruce S. Ross, Michael Joseph Sofia, Ganapati Reddy Pamulapati, Suguna Rachakonda, Hai-Ren Zhang, Byoung-Kwon Chun, Peiyuan Wang
  • Nucleoside phosphoramidates
    Patent number: 9284342
    Abstract: Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.
    Type: Grant
    Filed: June 24, 2013
    Date of Patent: March 15, 2016
    Assignee: Gilead Pharmasset LLC
    Inventors: Bruce S. Ross, Michael Joseph Sofia, Ganapati Reddy Pamulapati, Suguna Rachakonda, Hai-Ren Zhang, Byoung-Kwon Chun, Peiyuan Wang
  • BICYCLIC CYCLOHEXOSE NUCLEIC ACID ANALOGS
    Publication number: 20150191727
    Abstract: The present invention provides bicyclic cyclohexose nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. These bicyclic nucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance.
    Type: Application
    Filed: March 18, 2015
    Publication date: July 9, 2015
    Applicant: ISIS PHARMACEUTICALS, INC.
    Inventors: Michael T. Migawa, Punit P. Seth, Eric E. Swayze, Bruce S. Ross, Quanlai Song, Mingming Han
  • Bicyclic cyclohexose nucleic acid analogs
    Patent number: 9012421
    Abstract: The present invention provides bicyclic cyclohexose nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. These bicyclic nucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance.
    Type: Grant
    Filed: August 5, 2010
    Date of Patent: April 21, 2015
    Assignee: Isis Pharmaceuticals, Inc.
    Inventors: Michael T. Migawa, Punit P. Seth, Eric E. Swayze, Bruce S. Ross, Quanlai Song, Mingming Han
  • Stereoselective synthesis of phosphorus containing actives
    Patent number: 8859756
    Abstract: Disclosed herein are phosphorus-containing actives, their use as actives for treating diseases, and a stereoselective process for preparing the same. Also disclosed herein are useful synthetic intermediates and processes for preparing the same.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: October 14, 2014
    Assignee: Gilead Pharmasset LLC
    Inventors: Bruce S. Ross, Michael Joseph Sofia, Ganapati Reddy Pamulapati, Suguna Rachakonda, Hai-Ren Zhang
  • Nucleoside cyclicphosphates
    Patent number: 8759510
    Abstract: Cyclic phosphate of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomers, salts (acid or basic addition salts), hydrates, solvates, or crystalline forms thereof, represented by the following structure:
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: June 24, 2014
    Assignee: Gilead Pharmasset LLC
    Inventors: Jinfa Du, Dhanapalan Nagarathnam, Ganapati Reddy Pamulapati, Bruce S. Ross, Michael Joseph Sofia
  • Nucleoside phosphoramidates
    Patent number: 8735569
    Abstract: Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.
    Type: Grant
    Filed: July 8, 2013
    Date of Patent: May 27, 2014
    Assignee: Gilead Pharmasset LLC
    Inventors: Bruce S. Ross, Michael Joseph Sofia, Ganapati Reddy Pamulapati, Suguna Rachakonda, Hai-Ren Zhang, Byoung-Kwon Chun, Peiyuan Wang
  • Nucleoside phosphoramidates
    Patent number: 8618076
    Abstract: Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: December 31, 2013
    Assignee: Gilead Pharmasset LLC
    Inventors: Bruce S. Ross, Michael Joseph Sofia, Ganapati Reddy Pamulapati, Suguna Rachakonda, Hai-Ren Zhang, Byoung-Kwon Chun, Peiyuan Wang
  • NUCLEOSIDE PHOSPHORAMIDATES
    Publication number: 20130310551
    Abstract: Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.
    Type: Application
    Filed: July 8, 2013
    Publication date: November 21, 2013
    Inventors: Bruce S. Ross, Michael Joseph Sofia, Ganapati Reddy Pamulapati, Suguna Rachakonda, Hai-Ren Zhang, Byoung-Kwon Chun, Peiyuan Wang
  • NUCLEOSIDE PHOSPHORAMIDATES
    Publication number: 20130288997
    Abstract: Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.
    Type: Application
    Filed: June 24, 2013
    Publication date: October 31, 2013
    Inventors: Bruce S. Ross, Michael Joseph Sofia, Ganapati Reddy Pamulapati, Suguna Rachakonda, Hai-Ren Zhang, Byoung-Kwon Chun, Peiyuan Wang
  • Purine nucleoside phosphoramidate
    Patent number: 8563530
    Abstract: Disclosed herein is a compound represented by formula 1 or its hydrate thereof in crystalline or crystal-like form.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: October 22, 2013
    Assignee: Gilead Pharmassel LLC
    Inventors: Wonsuk Chang, Devan Naduthambi, Dhanapalan Nagarathnam, Ganapati Reddy Pamulapati, Bruce S. Ross, Michael Joseph Sofia, Hai-Ren Zhang
  • Bicyclic cyclohexitol nucleic acid analogs
    Patent number: 8530640
    Abstract: The present disclosure provides bicyclic cyclohexitol nucleoside analogs of formula I and oligomeric compounds comprising these nucleoside analogs. These bicyclic nucleoside analogs are expected to be useful for enhancing properties of oligomeric compounds including for example nuclease resistance.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: September 10, 2013
    Assignee: Isis Pharmaceuticals, Inc.
    Inventors: Punit P. Seth, Michael T. Migawa, Eric E. Swayze, Quanlai Song, Mingming Han, Bruce S. Ross
  • NUCLEOSIDE CYCLICPHOSPHATES
    Publication number: 20120258928
    Abstract: Cyclic phosphate of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomers, salts (acid or basic addition salts), hydrates, solvates, or crystalline forms thereof, represented by the following structure:
    Type: Application
    Filed: April 5, 2012
    Publication date: October 11, 2012
    Applicant: GILEAD PHARMASSET LLC
    Inventors: JINFA DU, DHANAPALAN NAGARATHNAM, GANAPATI REDDY PAMULAPATI, BRUCE S. ROSS, MICHAEL JOSEPH SOFIA
  • BICYCLIC CYCLOHEXOSE NUCLEIC ACID ANALOGS
    Publication number: 20120172414
    Abstract: The present invention provides bicyclic cyclohexose nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. These bicyclic nucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance.
    Type: Application
    Filed: August 5, 2010
    Publication date: July 5, 2012
    Applicant: Isis Pharmaceuticals, Inc.
    Inventors: Michael T. Migawa, Punit P. Seth, Eric E. Swayze, Bruce S. Ross, Quanlai Song, Mingming Han
  • Nucleoside cyclicphosphates
    Patent number: 8173621
    Abstract: Cyclic phosphate of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomers, salts (acid or basic addition salts), hydrates, solvates, or crystalline forms thereof, represented by the following structure:
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: May 8, 2012
    Assignee: Gilead Pharmasset LLC
    Inventors: Jinfa Du, Dhanapalan Nagarathnam, Ganapati Reddy Pamulapati, Bruce S. Ross, Michael Joseph Sofia
  • PURINE NUCLEOSIDE PHOSPHORAMIDATE
    Publication number: 20110257121
    Abstract: Disclosed herein is a compound represented by formula 1 or its hydrate thereof in crystalline or crystal-like form.
    Type: Application
    Filed: March 31, 2011
    Publication date: October 20, 2011
    Applicant: PHARMASSET, INC.
    Inventors: WONSUK CHANG, DEVAN NADUTHAMBI, DHANAPALAN NAGARATHNAM, GANAPATI REDDY PAMULAPATI, BRUCE S. ROSS, MICHAEL JOSEPH SOFIA, HAI-REN ZHANG
  • NUCLEOSIDE PHOSPHORAMIDATES
    Publication number: 20110251152
    Abstract: Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.
    Type: Application
    Filed: March 31, 2011
    Publication date: October 13, 2011
    Applicant: PHARMASSET, INC.
    Inventors: Bruce S. Ross, Michael Joseph Sofia, Ganapati Reddy Pamulapati, Suguna Rachakonda, Hai-Ren Zhang, Byoung-Kwon Chun, Peiyuan Wang
  • STEREOSELECTIVE SYNTHESIS OF PHOSPHORUS CONTAINING ACTIVES
    Publication number: 20110245484
    Abstract: Disclosed herein are phosphorus-containing actives, their use as actives for treating diseases, and a stereoselective process for preparing the same. Also disclosed herein are useful synthetic intermediates and processes for preparing the same.
    Type: Application
    Filed: March 31, 2011
    Publication date: October 6, 2011
    Applicant: PHARMASSET, INC.
    Inventors: BRUCE S. ROSS, MICHAEL JOSEPH SOFIA, GANAPATI REDDY PAMULAPATI, SUGUNA RACHAKONDA, HAI-REN ZHANG
  • BICYCLIC CYCLOHEXITOL NUCLEIC ACID ANALOGS
    Publication number: 20110077390
    Abstract: The present disclosure provides bicyclic cyclohexitol nucleoside analogs of formula I and oligomeric compounds comprising these nucleoside analogs. These bicyclic nucleoside analogs are expected to be useful for enhancing properties of oligomeric compounds including for example nuclease resistance.
    Type: Application
    Filed: February 6, 2009
    Publication date: March 31, 2011
    Applicant: ISIS PHARMACEUTICALS, INC.
    Inventors: Punit P. Seth, Michael T. Migawa, Eric E. Swayze, Quanlai Song, Mingmin Han, Bruce S. Ross