Patents by Inventor Bruce Trapp

Bruce Trapp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION
    Publication number: 20230257350
    Abstract: A method of promoting the differentiation of an oligodendrocyte precursor cell is disclosed herein. The method includes administering to the oligodendrocyte precursor cell an effective amount of a compound capable of promoting oligodendrocyte precursor cell differentiation. Also disclosed herein is a method of treating a neurodegenerative disorder, including a demyelinating disease such as multiple sclerosis, in a subject in need thereof, comprising administering to the subject a compound disclosed herein.
    Type: Application
    Filed: July 2, 2021
    Publication date: August 17, 2023
    Inventors: Bruce Trapp, Satish Medicetty, Chunyang Brian Bai
  • Multipotent neural stem cells
    Patent number: 8383098
    Abstract: An isolated multipotent neural stem cells has a phenotype identified by expression of the protein ?-tubulin IV and Olig2 and the absence of the proteins NG2, PLP, and GFAP.
    Type: Grant
    Filed: August 30, 2010
    Date of Patent: February 26, 2013
    Assignee: Case Western REserve University
    Inventors: Bruce Trapp, Robert Miller
  • COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION
    Publication number: 20120172375
    Abstract: A method of promoting the differentiation of an oligodendrocyte precursor cell. The method includes administering to the oligodendrocyte precursor cell an effective amount of a compound capable of promoting oligodendrocyte precursor cell differentiation.
    Type: Application
    Filed: November 9, 2009
    Publication date: July 5, 2012
    Inventors: Bruce Trapp, Wendy B. MacKlin, Carlos E. Pedraza, Elena K. Muratova, Victor V. Sokolov
  • MULTIPOTENT NEURAL STEM CELLS
    Publication number: 20120045832
    Abstract: An isolated multipotent neural stem cells has a phenotype identified by expression of the protein ?-tubulin IV and Olig2 and the absence of the proteins NG2, PLP, and GFAP.
    Type: Application
    Filed: August 30, 2010
    Publication date: February 23, 2012
    Inventors: Bruce Trapp, Robert Miller
  • Multipotent neural stem cells
    Patent number: 7803364
    Abstract: An isolated multipotent neural stem cells has a phenotype identified by expression of the protein ?-tubulin IV and Olig2 and the absence of the proteins NG2, PLP, and GFAP.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: September 28, 2010
    Assignee: The Cleveland Clinic Foundation
    Inventors: Bruce Trapp, Robert Miller
  • Multipotent neural stem cells
    Publication number: 20070231302
    Abstract: An isolated multipotent neural stem cells has a phenotype identified by expression of the protein ?-tubulin IV and Olig2 and the absence of the proteins NG2, PLP, and GFAP.
    Type: Application
    Filed: November 17, 2006
    Publication date: October 4, 2007
    Inventors: Bruce Trapp, Robert Miller