Patents by Inventor Bruce W. Ennis

Bruce W. Ennis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • JNK inhibitors for use in combination therapy for treating or managing proliferative disorders and cancers
    Patent number: 7351729
    Abstract: The present invention relates to methods and compositions designed for the treatment, management or prevention of cancer. The methods of the invention comprise the administration of an effective amount of one or more inhibitors of JNK in combination with the administration of an effective amount of one or more other agents useful for cancer therapy. The invention also provides pharmaceutical compositions comprising one or more inhibitors of JNK in combination with one or more other agents useful for cancer therapy. In particular, the invention is directed to methods of treatment and prevention of cancer by the administration of an effective amount of one or more inhibitors of JNK in combination with standard and experimental chemotherapies, hormonal therapies, bone marrow transplants, stem cell replacement therapies, biological therapies/immunotherapies and/or radiation therapies for treatment or prevention of cancer.
    Type: Grant
    Filed: March 7, 2003
    Date of Patent: April 1, 2008
    Assignee: Signal Pharmaceuticals, LLC
    Inventors: Bernd M. Stein, John K. Westwick, Bruce W. Ennis
  • Combination therapy for treating, preventing or managing proliferative disorders and cancers
    Publication number: 20040067953
    Abstract: The present invention relates to methods and compositions designed for the treatment, management or prevention of cancer. The methods of the invention comprise the administration of an effective amount of one or more inhibitors of JNK in combination with the administration of an effective amount of one or more other agents useful for cancer therapy. The invention also provides pharmaceutical compositions comprising one or more inhibitors of JNK in combination with one or more other agents useful for cancer therapy. In particular, the invention is directed to methods of treatment and prevention of cancer by the administration of an effective amount of one or more inhibitors of JNK in combination with standard and experimental chemotherapies, hormonal therapies, bone marrow transplants, stem cell replacement therapies, biological therapies/immunotherapies and/or radiation therapies for treatment or prevention of cancer.
    Type: Application
    Filed: March 7, 2003
    Publication date: April 8, 2004
    Inventors: Bernd M. Stein, John K. Westwick, Bruce W. Ennis