Patents by Inventor Bruce Wines

Bruce Wines has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multimeric Fc Receptor Polypeptides
    Publication number: 20080008700
    Abstract: A soluble multimeric protein or polypeptide is disclosed that is able to inhibit interaction of leukocyte Fc? receptors (Fc?R) and immunoglobulin G (IgG). The protein or polypeptide comprises two or more linked Fc binding regions, at least one of which is derived from an Fc?R type receptor and, particularly, Fc?RIIa. Also described are polynucleotide molecules encoding the protein or polypeptide and the use thereof in methods of treating a subject for an immune-complex (IC)-mediated inflammatory disease.
    Type: Application
    Filed: June 13, 2007
    Publication date: January 10, 2008
    Applicant: TRILLIUM THERAPEUTICS, INC.
    Inventors: Phillip Hogarth, Bruce Wines
  • CRYSTAL STRUCTURES AND MODELS FOR Fc RECEPTORS AND USES THEREOF IN THE DESIGN OR IDENTIFICATION OF Fc RECEPTOR MODULATOR COMPOUNDS
    Publication number: 20070048791
    Abstract: The invention relates to the determination of the three-dimensional structures of Fc receptor proteins, particularly wild-type Fc?RIIa, by X-ray crystallography and the use of the structure in identifying and modifying agents for modulating the biological activity of Fc receptors. Also disclosed is a novel dimeric structure for Fc?RIIa and novel target sites for agents for modulating the biological activity of Fc receptor proteins.
    Type: Application
    Filed: August 9, 2006
    Publication date: March 1, 2007
    Applicant: The Macfarlane Burnet Institute for Medical Research and Public Health Ltd.
    Inventors: Geoffrey Pietersz, Tessa Bradford, Phillip Hogarth, Bruce Wines, Paul Ramsland