Patents by Inventor Bruno BIETH

Bruno BIETH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING CHRONIC SPONTANEOUS URTICARIA USING A BRUTON'S TYROSINE KINASE INHIBITOR
    Publication number: 20250375446
    Abstract: The present disclosure relates to methods for treating Chronic Spontaneous Urticaria using a compound of Formula (I) or a pharmaceutically acceptable salt thereof. Also disclosed herein is a compound of Formula (I) or a pharmaceutically acceptable salt thereof, for treating Chronic Spontaneous Urticaria patients, as well as medicaments, dosing regimens, pharmaceutical formulations, dosage forms, and kits for use in the disclosed uses and methods.
    Type: Application
    Filed: August 27, 2025
    Publication date: December 11, 2025
    Inventors: Souvik BHATTACHARYA, Bruno BIETH, Maciej CABANSKI, Bruno CENNI, Stefan DE BUCK, Martin KAUL, Arvind KINHIKAR, Andrijana RADIVOJEVIC, Thomas SEVERIN, Julian STORIM, Alessandra VITALITI GARAMI
  • METHODS OF TREATING SJOGREN'S SYNDROME USING A BRUTON'S TYROSINE KINASE INHIBITOR
    Publication number: 20250339428
    Abstract: The present disclosure relates to methods for treating Sjögren's Syndrome disease using a compound of Formula (I) or a pharmaceutically acceptable salt thereof. Also disclosed herein a compound of Formula (I) or a pharmaceutically acceptable salt thereof, for treating Sjögren's Syndrome patients, as well as medicaments, dosing regimens, pharmaceutical formulations, dosage forms, and kits for use in the disclosed uses and methods.
    Type: Application
    Filed: July 14, 2025
    Publication date: November 6, 2025
    Inventors: Souvik BHATTACHARYA, Bruno BIETH, Maciej CABANSKI, Bruno CENNI, Stefan DE BUCK, Martin KAUL, Arvind KINHIKAR, Andrijana RADIVOJEVIC, Alessandra VITALITI GARAMI
  • Methods of treating chronic spontaneous urticaria using a bruton's tyrosine kinase inhibitor
    Patent number: 12419889
    Abstract: The present disclosure relates to methods for treating Chronic Spontaneous Urticaria using a compound of Formula (I) or a pharmaceutically acceptable salt thereof. Also disclosed herein is a compound of Formula (I) or a pharmaceutically acceptable salt thereof, for treating Chronic Spontaneous Urticaria patients, as well as medicaments, dosing regimens, pharmaceutical formulations, dosage forms, and kits for use in the disclosed uses and methods.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: September 23, 2025
    Assignee: Novartis AG
    Inventors: Souvik Bhattacharya, Bruno Bieth, Maciej Cabanski, Bruno Cenni, Stefan De Buck, Martin Kaul, Arvind Kinhikar, Andrijana Radivojevic, Thomas Severin, Julian Storim, Alessandra Vitaliti Garami
  • Methods of treating Sjögren's syndrome using a Bruton's tyrosine kinase inhibitor
    Patent number: 12383556
    Abstract: The present disclosure relates to methods for treating Sjögren's Syndrome disease using a compound of Formula (I) or a pharmaceutically acceptable salt thereof. Also disclosed herein a compound of Formula (I) or a pharmaceutically acceptable salt thereof, for treating Sjögren's Syndrome patients, as well as medicaments, dosing regimens, pharmaceutical formulations, dosage forms, and kits for use in the disclosed uses and methods.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: August 12, 2025
    Assignee: Novartis AG
    Inventors: Souvik Bhattacharya, Bruno Bieth, Maciej Cabanski, Bruno Cenni, Stefan De Buck, Martin Kaul, Arvind Kinhikar, Andrijana Radivojevic, Alessandra Vitaliti Garami
  • REMIBRUTINIB FOR USE IN THE TREATMENT OF HIDRADENITIS SUPPURATIVA
    Publication number: 20250099465
    Abstract: The present disclosure relates to methods for treating and/or preventing Hidradenitis Suppurativa in a subject having such disease or condition comprising administering a therapeutically effective dose of LOU064. Also disclosed are medicaments, dosing regimens, pharmaceutical compositions, combinations, dosage forms, and kits for use in the disclosed uses and methods.
    Type: Application
    Filed: February 27, 2023
    Publication date: March 27, 2025
    Inventors: Souvik BHATTACHARYA, Bruno BIETH, Bruno CENNI, Gordon GRAHAM, Michael JUHNKE, Christian LOESCHE, Karin RAPP, Kim-Hien SIN, Jonas Benjamin ZIERER
  • METHODS OF TREATMENT USING LOU064
    Publication number: 20250032488
    Abstract: The present disclosure relates to methods of treating and/or preventing IgE driven allergic reaction to one or more allergens, preferably food allergens, in subjects having such disease or condition, comprising administering a therapeuticallly effective dose of LOU064.
    Type: Application
    Filed: December 12, 2022
    Publication date: January 30, 2025
    Inventors: Souvik BHATTACHARYA, Bruno BIETH, Bruno CENNI, Gordon GRAHAM, Michael JUHNKE, Monica LIGUEROS-SAYLAN, Dan Dragos MIHAILESCU, Karin RAPP, Kim-Hien Sin, Bridget Danielle STUART
  • LOU064 FOR TREATING MULTIPLE SCLEROSIS
    Publication number: 20240350489
    Abstract: The invention concerns method of treating multiple sclerosis (MS) by administering a therapeutically effective dose of LOU064 or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: September 1, 2022
    Publication date: October 24, 2024
    Inventors: Souvik BHATTACHARYA, Bruno BIETH, Bruno CENNI, Peter END, Gordon GRAHAM, Michael JUHNKE, Rajesh Singh KARAN, Allison Donna MANN, Etienne PIGEOLET, Karin RAPP, Kim-Hien SIN, Huixin YU, Ying ZHANG
  • METHODS OF TREATING CHRONIC SPONTANEOUS URTICARIA USING A BRUTON'S TYROSINE KINASE INHIBITOR
    Publication number: 20220184074
    Abstract: The present disclosure relates to methods for treating Chronic Spontaneous Urticaria using a compound of Formula (I) or a pharmaceutically acceptable salt thereof. Also disclosed herein is a compound of Formula (I) or a pharmaceutically acceptable salt thereof, for treating Chronic Spontaneous Urticaria patients, as well as medicaments, dosing regimens, pharmaceutical formulations, dosage forms, and kits for use in the disclosed uses and methods.
    Type: Application
    Filed: May 20, 2020
    Publication date: June 16, 2022
    Inventors: Souvik BHATTACHARYA, Bruno BIETH, Maciej CABANSKI, Bruno CENNI, Stefan DE BUCK, Martin KAUL, Arvind KINHIKAR, Andrijana RADIVOJEVIC, Thomas SEVERIN, Julian STORIM, Alessandra VITALITI GARAMI
  • METHODS OF TREATING SJOGREN'S SYNDROME USING A BRUTON'S TYROSINE KINASE INHIBITOR
    Publication number: 20220175772
    Abstract: The present disclosure relates to methods for treating Sjögren's Syndrome disease using a compound of Formula (I) or a pharmaceutically acceptable salt thereof. Also disclosed herein a compound of Formula (I) or a pharmaceutically acceptable salt thereof, for treating Sjögren's Syndrome patients, as well as medicaments, dosing regimens, pharmaceutical formulations, dosage forms, and kits for use in the disclosed uses and methods.
    Type: Application
    Filed: May 20, 2020
    Publication date: June 9, 2022
    Inventors: Souvik BHATTACHARYA, Bruno BIETH, Maciej CABANSKI, Bruno CENNI, Stefan DE BUCK, Martin KAUL, Arvind KINHIKAR, Andrijana RADIVOJEVIC, Alessandra VITALITI GARAMI
  • USE OF INHIBITORS OF THE ACTIVITY OR FUNCTION OF PI3K FOR THE TREATMENT OF PRIMARY SJOGREN'S SYNDROME
    Publication number: 20190038628
    Abstract: The invention relates to the use of 1-{(S)-3-[6-(6-methoxy-5-trifluoromethyl-pyridin-3-yl)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-ylamino]-pyrrolidin-1-yl}-propan-1-one or pharmaceutically acceptable salts thereof for the treatment of primary Sjögren's Syndrome.
    Type: Application
    Filed: February 10, 2017
    Publication date: February 7, 2019
    Inventors: Bruno BIETH, Christoph BURKHART, Andreas CHRIST, Stefan DE BUCK, Christoph KALIS, Sam LINDGREN