Patents by Inventor Bruno CASSINAT

Bruno CASSINAT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT PATIENTS SUFFERING FROM MYELOPROLIFERATIVE DISORDERS
    Publication number: 20190374611
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of myeloproliferative disorders in patients presenting a dysregulation of the JAK2-STAT signalling pathway. Using MPN mouse model and clonogenic methyl-cellulose cultures of patient progenitors, the inventors demonstrate that combining ARS with IFN improves most of the benefits provided by IFN alone during MPN treatment. In particular, the present invention relates to a method of treating a myeloproliferative disorder in a patient presenting a dysregulation of the JAK2-STAT signalling pathway comprising administering to the patient a therapeutically effective combination of an interferon polypeptide and an arsenic compound.
    Type: Application
    Filed: January 17, 2018
    Publication date: December 12, 2019
    Inventors: Hugues DE THE, Bruno CASSINAT, Valérie LALLEMAND-BREITENBACH, Isabelle PLO, Jean-Luc VILLEVAL, Jean-Jacques KILADJIAN