Patents by Inventor Bruno COSTA DA SILVA

Bruno COSTA DA SILVA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230067928
    Abstract: The present invention is directed to a method for identifying an individual who is at risk for developing metastatic liver disease that involves measuring, in a sample isolated from the individual, exosomal levels of one or more markers of metastatic liver disease. Kits for carrying out this method are also disclosed. The present invention also relates to a method of preventing metastatic liver disease in an individual who are at risk for developing the disease that involves administering one or more inhibitors of liver premetastatic niche formation.
    Type: Application
    Filed: July 21, 2022
    Publication date: March 2, 2023
    Inventors: David C. LYDEN, Bruno COSTA DA SILVA
  • Patent number: 11397182
    Abstract: The present invention is directed to a method for identifying an individual who is at risk for developing metastatic liver disease that involves measuring, in a sample isolated from the individual, exosomal levels of one or more markers of metastatic liver disease. Kits for carrying out this method are also disclosed. The present invention also relates to a method of preventing metastatic liver disease in an individual who are at risk for developing the disease that involves administering one or more inhibitors of liver pre-metastatic niche formation.
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: July 26, 2022
    Assignee: CORNELL UNIVERSITY
    Inventors: David C. Lyden, Bruno Costa Da Silva
  • Publication number: 20180231558
    Abstract: The present invention is directed to a method for identifying an individual who is at risk for developing metastatic liver disease that involves measuring, in a sample isolated from the individual, exosomal levels of one or more markers of metastatic liver disease. Kits for carrying out this method are also disclosed. The present invention also relates to a method of preventing metastatic liver disease in an individual who are at risk for developing the disease that involves administering one or more inhibitors of liver pre-metastatic niche formation.
    Type: Application
    Filed: October 7, 2015
    Publication date: August 16, 2018
    Inventors: David C. LYDEN, Bruno COSTA DA SILVA