Patents by Inventor Bruno Filipe Oliveira Nascimento

Bruno Filipe Oliveira Nascimento has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof
    Patent number: 11584727
    Abstract: Compounds are provided for stabilizing protein transthyretin (TTR) and inhibiting amyloid fibril formation, for example, transthyretin-mediated amyloid fibril formation, and for treating, preventing, or ameliorating one or more symptoms of amyloid diseases, for example, transthyretin-related amyloidosis (ATTR).
    Type: Grant
    Filed: August 18, 2021
    Date of Patent: February 21, 2023
    Assignee: BSIM Therapeutics, S.A.
    Inventors: Rui Manuel Pontes Meireles Ferreira de Brito, Carlos José Vieira Simões, Teresa Margarida Vasconcelos Dias de Pinho e Melo, Bruno Lourenço da Silva Victor, Zaida Catarina Lourenço de Almeida, Ana Lúcia Cabral Cardoso Lopes, Bruno Filipe Oliveira Nascimento
  • 2-THIOXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF
    Publication number: 20220267286
    Abstract: Compounds are provided for stabilizing protein transthyretin (TTR) and inhibiting amyloid fibril formation, for example, transthyretin-mediated amyloid fibril formation, and for treating, preventing, or ameliorating one or more symptoms of amyloid diseases, for example, transthyretin-related amyloidosis (ATTR).
    Type: Application
    Filed: August 18, 2021
    Publication date: August 25, 2022
    Applicant: BSIM Therapeutics, S.A.
    Inventors: Rui Manuel Pontes Meireles Ferreira de Brito, Carlos José Vieira Simões, Teresa Margarida Vasconcelos Dias de Pinho e Melo, Bruno Lourenço da Silva Victor, Zaida Catarina Lourenço de Almeida, Ana Lúcia Cabral Cardoso Lopes, Bruno Filipe Oliveira Nascimento
  • 2-THIOXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF
    Publication number: 20220041566
    Abstract: Compounds are provided for stabilizing protein transthyretin (TTR) and inhibiting amyloid fibril formation, for example, transthyretin-mediated amyloid fibril formation, and for treating, preventing, or ameliorating one or more symptoms of amyloid diseases, for example, transthyretin-related amyloidosis (ATTR).
    Type: Application
    Filed: August 18, 2021
    Publication date: February 10, 2022
    Applicant: BSIM Therapeutics, S.A.
    Inventors: Rui Manuel Pontes Meireles Ferreira de Brito, Carlos José Vieira Simões, Teresa Margarida Vasconcelos Dias de Pinho e Melo, Bruno Lourenço da Silva Victor, Zaida Catarina Lourenço de Almeida, Ana Lúcia Cabral Cardos Lopes, Bruno Filipe Oliveira Nascimento
  • 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof
    Patent number: 11117877
    Abstract: Compounds of formula (II) are provided for stabilizing protein transthyretin (TTR) and inhibiting amyloid fibril formation, for example, transthyretin-mediated amyloid fibril formation, and for treating, preventing, or ameliorating one or more symptoms of amyloid diseases, for example, transthyretin-related amyloidosis (ATTR).
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: September 14, 2021
    Assignee: BSIM Therapeutics, S.A.
    Inventors: Rui Manuel Pontes Meireles Ferreira de Brito, Carlos José Vieira Simões, Teresa Margarida Vasconcelos Dias de Pinho e Melo, Bruno Lourenço da Silva Victor, Zaida Catarina Lourenço de Almeida, Ana Lúcia Cabral Cardoso Lopes, Bruno Filipe Oliveira Nascimento