Patents by Inventor Bruno Filoche

Bruno Filoche has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,4-Dihydropyridine-Fused Heterocycles, Process for Preparing the Same, Use and Compositions Containing Them
    Publication number: 20080261969
    Abstract: This invention relates to compounds of formula (I) to processes for the preparation of such compounds, to pharmaceutical compositions comprising such compounds, and to methods of treatment comprising administering of such compounds.
    Type: Application
    Filed: January 15, 2008
    Publication date: October 23, 2008
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Jacques MAUGER, Anil NAIR, Nina MA, Kirsten BJERGARDE, Bruno FILOCHE-ROMME, Odile ANGOUILLANT-BONIFACE, Serge MIGNANI, Jean-Christophe CARRY, Francois CLERC, Herve MINOUX, Laurent SCHIO, Cecile COMBEAU
  • Substituted Indoles, Compositions Containing Them, Method for the Production Thereof and Their Use
    Publication number: 20070259910
    Abstract: Compounds of formula (I): wherein R1, R5, R6, R7, Ar, L, A, and Q are as defined in the description, and to salts thereof, to compositions containing them, to the process for preparing them, and to their use as medicinal products, in particular as anticancer agents.
    Type: Application
    Filed: June 4, 2007
    Publication date: November 8, 2007
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Frank HALLEY, Catherine SOUAILLE, Michel TABART, Eric BACQUE, Fabrice VIVIANI, Baptiste RONAN, Jean-Philippe LETALLEC, Bruno FILOCHE-ROMME
  • Substituted Indazoles, Compositions Containing The Same, And The Preparation And Use Thereof
    Publication number: 20070161626
    Abstract: Disclosed are novel substituted indazole compounds, pharmaceutical compositions comprising such compounds, and methods of treatment comprising such compounds.
    Type: Application
    Filed: December 4, 2006
    Publication date: July 12, 2007
    Applicant: Aventis Pharma S.A.
    Inventors: Frank Halley, Michel Tabart, Herve Bouchard, Catherine Souaille, Alain Le Brun, Fabrice Viviani, Laurence Gauzy-Lazo, Pascal Desmazeau, Odile Angouillant-Boniface, Bruno Filoche-Romme
  • Novel pyrrolo (2,3-b)pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors
    Publication number: 20070093480
    Abstract: Novel compounds of formula (I): or pharmaceutically acceptable salts thereof, wherein R, R1, R2, R3, R4, R5, and R6 have the meanings given in the description, pharmaceutical compositions comprising said compounds and use thereof as protein kinase inhibitors.
    Type: Application
    Filed: September 29, 2006
    Publication date: April 26, 2007
    Applicant: Aventis Pharma S.A.
    Inventors: Sylvie Wentzler, Youssef El-Ahmad, Bruno Filoche-Romme, Conception Nemecek, Corinne Venot, Augustin Hittinger
  • Pharmaceutical compositions containing 3-aminoazetidine derivatives, novel derivatives and their preparation
    Patent number: 7132414
    Abstract: The present invention relates to pharmaceutical compositions containing, as active ingredient, a compound of formula: in which R1 represents a radical —NHCOR4 or —N(R5)—Y—R6, Y is CO or SO2, R4 represents a radical -alk-SO2—R11, -alk-SO2—CH?CH—R11 or Het substituted with —SO2—R11 or a phenyl radical substituted with —SO2—R11 or -alk-SO2—R11, R5 represents a hydrogen atom or an alkyl radical, R6 represents a phenylalkyl, Het or Ar radical, to the novel derivatives of formula (I) and to their preparation, as well s to their use in treating various disorders of the nervous system.
    Type: Grant
    Filed: February 4, 2004
    Date of Patent: November 7, 2006
    Assignee: Aventis Pharma S.A.
    Inventors: Daniel Achard, Herve Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael R. Myers
  • Novel organophosphorus derivatives of indazoles and use thereof as medicinal products
    Publication number: 20050137171
    Abstract: The present invention relates in particular to novel chemical compounds, particularly to novel organophosphorus derivatives of indazoles, to the compositions containing them, and to the use thereof as medicinal products for treating cancers.
    Type: Application
    Filed: December 17, 2004
    Publication date: June 23, 2005
    Applicant: Aventis Pharma S.A.
    Inventors: Marie-Pierre Cherrier, Francois Clerc, Alain Commercon, Patrick Mailliet, Herve Minoux, Bruno Filoche-Romme
  • Pharmacological uses of azetidine derivatives
    Publication number: 20050130953
    Abstract: A method of treating or preventing Alzheimer's disease, Parkinson's Disease and/or schizophrenia, this method comprising administering to a patient in need of such treatment a compound of formula: in which R, R3 and R4 are as defined in the specification.
    Type: Application
    Filed: November 12, 2004
    Publication date: June 16, 2005
    Applicant: Aventis Pharma S.A.
    Inventors: Daniel Achard, Herve Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael Myers
  • Pharmacological uses of azetidine derivatives
    Patent number: 6872717
    Abstract: A method of treating or preventing obesity, this method comprising administering to a patient in need of such treatment an effective amount of a compound of formula in which R, R3 and R4 are as defined in the specification.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: March 29, 2005
    Assignee: Aventis Pharma S.A.
    Inventors: Daniel Achard, Hervé Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael R. Myers
  • Substituted indazoles, compositions containing them, method of production and use
    Publication number: 20050059722
    Abstract: Substituted indazoles, compositions containing them, method of production and use. The present invention relates in particular to novel specific substituted indazoles exhibiting kinase-inhibiting activity, having therapeutic activity, in particular in oncology.
    Type: Application
    Filed: October 13, 2004
    Publication date: March 17, 2005
    Applicant: Aventis Pharma S.A.
    Inventors: Dominique Damour, Jean-Christophe Carry, Patrick Nemecek, Corinne Terrier, Frederico Nardi, Bruno Filoche, Marie-Pierre Cherrier, Daniel Bezard
  • Substituted indazoles, compositions containing them, method of production and use
    Patent number: 6858638
    Abstract: Substituted indazoles, compositions containing them, method of production and use. The present invention relates in particular to novel specific substituted indazoles exhibiting kinase-inhibiting activity, having therapeutic activity, in particlar in oncology.
    Type: Grant
    Filed: March 11, 2003
    Date of Patent: February 22, 2005
    Assignee: Aventis Pharma S.A.
    Inventors: Dominique Damour, Jean-Christophe Carry, Patrick Nemecek, Corinne Terrier, Frederico Nardi, Bruno Filoche, Marie-Pierre Cherrier, Daniel Bezard
  • Polyhydroxyalkylpyrazine derivatives, their preparation and medicaments comprising them
    Publication number: 20040209890
    Abstract: The present invention relates to compounds of formula (I) 1
    Type: Application
    Filed: November 21, 2001
    Publication date: October 21, 2004
    Inventors: Georges Bashiardes, Jean-Christophe Carry, Michel Evers, Bruno Filoche, Serge Mignani
  • Pharmaceutical compositions containing 3-aminoazetidine derivatives, novel derivatives and their preparation
    Publication number: 20040157823
    Abstract: The present invention relates to pharmaceutical compositions containing, as active ingredient, a compound of formula: 1
    Type: Application
    Filed: February 4, 2004
    Publication date: August 12, 2004
    Applicant: Aventis Pharma S.A.
    Inventors: Daniel Achard, Herve Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael R. Myers
  • Substituted indazoles, compositions containing them, method of production and use
    Publication number: 20040106667
    Abstract: Substituted indazoles, compositions containing them, method of production and use. The present invention relates in particular to novel specific substituted indazoles exhibiting kinase-inhibiting activity, having therapeutic activity, in particlar in oncology.
    Type: Application
    Filed: March 11, 2003
    Publication date: June 3, 2004
    Inventors: Dominique Damour, Jean-Christophe Carry, Patrick Nemecek, Corinne Terrier, Frederico Nardi, Bruno Filoche, Marie-Pierre Cherrier, Daniel Bezard
  • Pharmaceutical compositions containing 3-aminoazetidine derivatives, novel derivatives and their preparation
    Patent number: 6734176
    Abstract: The present invention relates to pharmaceutical compositions containing, as active ingredient, a compound of formula: in which R1 represents a radical —NHCOR4 or —N(R5)—Y—R6, Y is CO or SO2, R4 represents a radical -alk-SO2—R11, -alk-SO2—CH═CH—R11 or Het substituted with —SO2—R11 or a phenyl radical substituted with —SO2—R11 or -alk-SO2—R11, R5 represents a hydrogen atom or an alkyl radical, R6 represents a phenylalkyl, Het or Ar radical, to the novel derivatives of formula (I) and to their preparation, as well s to their use in treating various disorders of the nervous system.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: May 11, 2004
    Assignee: Aventis Pharma S.A.
    Inventors: Daniel Achard, Hervé Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael R. Myers
  • Pharmaceutical compositions containing 3-aminoazetidine derivatives, novel derivatives and their preparation
    Publication number: 20030119810
    Abstract: The present invention relates to pharmaceutical compositions containing, as active ingredient, a compound of formula: 1
    Type: Application
    Filed: December 17, 2002
    Publication date: June 26, 2003
    Inventors: Daniel Achard, Herve Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael R. Myers
  • Pharmaceutical compositions containing 3-aminoazetidine derivatives, novel derivatives and their preparation
    Patent number: 6566356
    Abstract: The present invention relates to pharmaceutical compositions containing, as active ingredient, a compound of formula: in which R1 represents a radical —NHCOR4 or —N(R5)—Y—R6, Y is CO or SO2, R4 represents a radical -alk-SO2—R11, -alk-SO2—CH═CH—R11 or Het substituted with —SO2—R11 or a phenyl radical substituted with —SO2—R11 or -alk-SO2—R11, R5 represents a hydrogen atom or an alkyl radical, R6 represents a phenylalkyl, Het or Ar radical, to the novel derivatives of formula (I) and to their preparation.
    Type: Grant
    Filed: March 2, 2001
    Date of Patent: May 20, 2003
    Assignee: Aventis Pharma S.A.
    Inventors: Daniel Achard, Hervé Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael R. Myers
  • Azetidine derivatives, their preparation and pharmaceutical compositions containing them
    Publication number: 20030055033
    Abstract: Compounds of formula: 1
    Type: Application
    Filed: September 12, 2002
    Publication date: March 20, 2003
    Inventors: Daniel Achard, Herve Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael R. Myers
  • Azetidine derivatives, their preparation and pharmaceutical compositions containing them
    Patent number: 6479479
    Abstract: Compounds of formula: in which R represents a CR1R2, C═C(R5)SO2R6 or C═C(R7)SO2alk radical, their preparation and the pharmaceutical compositions containing them.
    Type: Grant
    Filed: March 2, 2001
    Date of Patent: November 12, 2002
    Assignee: Aventis Pharma S.A.
    Inventors: Daniel Achard, Hervé Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael R. Myers
  • Polyhydroxyalkylpyrazine derivatives and their preparation and medicines containing them
    Patent number: 6407110
    Abstract: The invention concerns medicines containing as active principle at least a compound of formula (I): wherein either R2 represents a —CH2—(CHOH)2—CH3 chain and R3 represents a hydrogen atom or R2 represents a hydrogen atom and R3 represents a —CH2—(CHOH)2—CH3 chain or one of its stereoisomers or one of its salts, the novel compounds of formula (I), their stereoisomers, their salts and their preparation.
    Type: Grant
    Filed: January 11, 2001
    Date of Patent: June 18, 2002
    Assignee: Aventis Pharma S.A.
    Inventors: Georges Bashiardes, Jean-Christophe Carry, Michel Evers, Bruno Filoche, Serge Mignani
  • Pyrazine derivatives, their preparation and medicaments containing them
    Patent number: 6399613
    Abstract: The invention concerns pyrazine derivatives of formula (1) in which a pharmaceutical composition comprising at least one compound of formula: in which R represents a nitrogen atom, R1 and R3 each represent the same radical selected from the group consisting of —CO—NR5R6, —CO—N(CH(CH2OH)2)2, —CO—N(CH2OH)2, —CO—N(CH2—CH(CH2OH)2)2, —CO—N(CH2—(CHOH)n—CH2OH)2 in which n is equal to 0, 1, 2, 3 or 4, —CH2—O—R6, —NR5—CO—R6, —CH2—NR5R6, —CH2—N(CH2OH)2, —CH2—N(CH2—(CHOH)y—CH2OH)2 in which y is equal to 0, 1, 2, 3 or 4, —CH2—N(CH(CH2OH)2)2 and —CH2—N(CH2—CH(CH2OH)2)2 and R2 and R4 each represents a hydrogen atom, R5 represents a hydrogen atom or an alkyl radical, R6 represents a radical —CH2—(CHOH)m—CH2OH in which m is equal to 0, 1, 2, 3 or 4, -alk-O-alk-CH2OH, -alk-O-alk, —CH(CH2OH)2,
    Type: Grant
    Filed: January 14, 2000
    Date of Patent: June 4, 2002
    Assignee: Aventis Pharma S.A.
    Inventors: Georges Bashiardes, Jean-Christophe Carry, Michel Evers, Bruno Filoche, Serge Mignani