Patents by Inventor Bruno Francois

Bruno Francois has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9188478
    Abstract: An apparatus and a method for detecting surface motion of an object subject to ultrasound are disclosed. The method comprises generating a laser beam, dividing the laser beam into a reference beam and an object beam to be directed onto the surface, thereby producing a scattered object beam, introducing a small-amplitude modulation in the optical path difference between the reference beam and the scattered object beam, detecting the interference between the scattered object beam and the phase modulated reference beam using a plurality of detecting elements to generate a plurality of electrical interference signals, wherein the electrical interference signals each comprise a wanted signal component indicative of the surface motion and a noise signal component, and processing the electrical interference signals to determine the surface motion of the object.
    Type: Grant
    Filed: February 8, 2013
    Date of Patent: November 17, 2015
    Assignee: Bossa Nova Technologies, LLC
    Inventor: Bruno François Pouet
  • Publication number: 20150131244
    Abstract: The electrical device (2, 202) according to the invention comprises a first electrical component (4) and a second electrical component (6) connected to each other via an electrical connection means (26) having an electrically insulating support plate (24), and a weld joint (22) deposited on the support plate (24). The weld joint (22) has a melting temperature (TO significantly lower than an ambient operating temperature (Ta) to which at least one of the two electrical components and the electrical connection means (26) are provided to be subjected. The electrical device (2) comprises a cement (28) that completely covers the exposed weld joint (22), the material of the cement (28) being chosen to maintain its adhesion and its tightness with respect to the weld joint (22) when the ambient operating temperature (Ta) is applied.
    Type: Application
    Filed: April 3, 2013
    Publication date: May 14, 2015
    Inventors: Sylvain Ballandras, Bruno Francois
  • Publication number: 20150099749
    Abstract: This invention concerns pyrimidine derivatives of formula having HIV (Human Immunodeficiency Virus) replication inhibiting properties, the preparation thereof and pharmaceutical compositions comprising these compounds.
    Type: Application
    Filed: December 10, 2014
    Publication date: April 9, 2015
    Inventors: Jerôme Emile Georges Guillemont, Mikaël Paugam, Bruno François Marie Delest
  • Patent number: 8933089
    Abstract: This invention concerns pyrimidine derivatives of formula having HIV (Human Immunodeficiency Virus) replication inhibiting properties, the preparation thereof and pharmaceutical compositions comprising these compounds.
    Type: Grant
    Filed: March 30, 2007
    Date of Patent: January 13, 2015
    Assignee: Janssen R & D Ireland
    Inventors: Jerôme Emile Georges Guillemont, Mikaël Paugam, Bruno François Marie Delest
  • Publication number: 20130208284
    Abstract: An apparatus and a method for detecting surface motion of an object subject to ultrasound are disclosed. The method comprises generating a laser beam, dividing the laser beam into a reference beam and an object beam to be directed onto the surface, thereby producing a scattered object beam, introducing a small-amplitude modulation in the optical path difference between the reference beam and the scattered object beam, detecting the interference between the scattered object beam and the phase modulated reference beam using a plurality of detecting elements to generate a plurality of electrical interference signals, wherein the electrical interference signals each comprise a wanted signal component indicative of the surface motion and a noise signal component, and processing the electrical interference signals to determine the surface motion of the object.
    Type: Application
    Filed: February 8, 2013
    Publication date: August 15, 2013
    Inventor: Bruno François Pouet
  • Publication number: 20130060228
    Abstract: The invention relates to a secure system for the perfusion of a body liquid, enabling a final control of compatability of a treatment with the patient and/or the medical situation previously diagnosed by a doctor, in a simple, efficient and energy-saving manner.
    Type: Application
    Filed: October 29, 2010
    Publication date: March 7, 2013
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ETABLISSEMENT FRANCAIS DU SANG, UNIVERSITE DE FRANCHE-COMTE, CENTRE HOSPITALIER UNIVERSITAIRE DE BESANCON
    Inventors: Lionel Pazart, Bruno François Marcel Wacogne, Christian Gérard Daniel Pieralli, Wilfrid Hervé Boireau, Pascal Charles Serge Morel
  • Publication number: 20130030263
    Abstract: The invention relates to a device (200) for taking a sample of a body fluid, such as blood, to be incorporated into a fluid circuit of a perfusion (100) of a patient who has a perfusion catheter (104), said device having a tubular structure (202) for connecting to the fluid circuit of the perfusion, provided with a zone for intubation, during use, of a sampling channel (300) comprising a distal end (301); and a means (203) for holding, during use, in the tubular structure, the part of the sampling channel (300) comprising a distal end (301) in such a way that the distal end (301) is oriented towards the perfusion catheter (104), in the direction of flow (F1) of the perfusion product (102), from a perfusion product reservoir (101) towards the perfusion catheter (104).
    Type: Application
    Filed: October 29, 2010
    Publication date: January 31, 2013
    Applicants: Centre National De La Recherche Scientifique, Etablissement Francais Du Sang, Universite de Franche-Comte, Centre Hospitalier Universitaire De Besancon
    Inventors: Lionel Pazart, Bruno François Marcel Wacogne, Christian Gérard Daniel Pieralli, Wilfrid Hervé Boireau, Pascal Charles Serge Morel
  • Patent number: 8321611
    Abstract: The invention generally pertains to onboard systems for passengers such as In-Flight Entertainment (IFE) Systems. The invention more particularly relates to a system and a method for accessing a personal computer device (3) onboard an aircraft and to an aircraft including such a system. The system includes an onboard network (12) to which is connected at least one interface (4) at a passenger's seat (si) and connection means. The system is arranged so that said interface and said personal computer device interact via the transmission of data on said onboard network.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: November 27, 2012
    Assignee: Airbus
    Inventors: Bruno Francois, Garrett Smith
  • Publication number: 20120264114
    Abstract: The invention relates to a disposable device comprising all of the reagents necessary for the detection of one or more particles of interest, and which can be incorporated in a detection system including simple means for the automatic management of fluids. For this purpose, the invention relates to a disposable device for the detection of one or more particles of interest present in a liquid sample, said device comprising a substrate provided with: a chamber for capturing the particle(s) of interest to be detected; a fluid channel connecting, upstream, the capture chamber to a buffer solution container, a liquid sample injection means and a container of labelling probes that can be secured to the particle(s) of interest to be detected; and a fluid channel connecting, downstream, the capture chamber to a container for the recovery of liquids which, during use, can flow from the capture chamber.
    Type: Application
    Filed: September 28, 2010
    Publication date: October 18, 2012
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Bruno François Marcel Wacogne, Christian Gérard Daniel Pieralli, Wilfrid Hervé Boireau, Thomas Mangeat, Alain Léon René Coaquette, Lionel Pazart, Christian Louis Davrinche, Serge Piranda, Jean-François Maurice Louis Delforge
  • Publication number: 20120190697
    Abstract: HIV replication inhibitors of formula wherein -a1=a2-a3=a4- is —CH?CH—CH?CH—, —N?CH—CH?CH—, —N?CH—N?CH—, —N?CH—CH?N—, —N?N—CH?CH—; -b1=b2-b3=b4- is —CH?CH—CH?CH—, —N?CH—CH?CH—, —N?CH—N?CH—, —N?CH—CH?N—, —N?N—CH?CH—; n and m is 0-4, R1 is hydrogen; aryl; formyl; C1-6alkylcarbonyl; C1-6alkyl; C1-6alkyloxycarbonyl; R2 is OH; halo; C1-6alkyl, C2-6alkenyl or C2-6alkynyl; substituted carbonyl; carboxyl; CN; nitro; amino; polyhalomethyl; polyhalomethylthio; —S(?O)pR6; C(?NH)R6; R2a is CN; amino; substituted amino; C1-6alkyl; halo; C1-6alkyloxy; carbonyl; —CH?N—NH—C(?O)—R16; C1-6alkyloxyC1-6alkyl; C2-6alkenyl or C2-6alkynyl; —C(?N—O—R8)—C1-4alkyl; R7 or —X—R7; R3 is CN; amino; C1-6alkyl; halo; C1-6alkyloxy; substituted carbonyl; —CH?N—NH—C(?O)—R16; substituted C1-6alkyl; C1-6alkyloxyC1-6alkyl; substituted C2-6alkenyl or C2-6alkynyl; —C(?N—O—R8)—C1-4alkyl; R7; —X—R7; R4 is halo; OH; C1-6alkyl, C2-6alkenyl or C2-6alkynyl; C3-7cycloalkyl; C1-6alkyloxy; CN; nitro; polyhaloC1-6alkyl; polyhaloC1-6alkyloxy; substituted
    Type: Application
    Filed: March 2, 2012
    Publication date: July 26, 2012
    Inventors: Jerôme Emile Georges GUILLEMONT, Mikaël Paugam, Bruno Francois Marie Delest, Jan Heeres, Paulus Joannes Lewi, Frank Xavier Jozef Herwig Arts
  • Patent number: 8153640
    Abstract: HIV replication inhibitors of formula N-oxides, pharmaceutically acceptable addition salts, quaternary amines or stereoisomeric forms thereof, wherein -a1=a2-a3=a4- is —CH?CH—CH?CH—, —N?CH—CH?CH—, —N?CH—N?CH—, —N?CH—CH?N—, —N?N—CH?CH—; -b1=b2-b3=b4- is —CH?CH—CH?CH—, —N?CH—CH?CH—, —N?CH—N?CH—, —N?CH—CH?N—, —N?N—CH?CH—; n and m is 0, 1, 2, 3 and in certain cases also 4; R1 is hydrogen; aryl; formyl; C1-6alkylcarbonyl; optionally substituted C1-6alkyl; C1-6alkyloxycarbonyl; R2 is OH; halo; optionally substituted C1-6alkyl, C2-6alkenyl or C2-6alkynyl; substituted carbonyl; carboxyl; CN; nitro; amino; substituted amino; polyhalomethyl; polyhalomethylthio; —S(?O)pR6; C(?NH)R6; R2a is CN; amino; substituted amino; optionally substituted C1-6alkyl; halo; optionally substituted C1-6alkyloxy; substituted carbonyl; —CH?N—NH—C(?O)—R16; optionally substituted C1-6alkyloxyC1-6alkyl; substituted C2-6alkenyl or C2-6alkynyl; —C(?N—O—R8)—C1-4alkyl; R7 or —X—R7; R3 is CN; amino; C1-6alkyl; halo; optionally substituted C1-6
    Type: Grant
    Filed: October 27, 2005
    Date of Patent: April 10, 2012
    Assignee: Tibotec Pharmaceuticals Ltd.
    Inventors: Jerôme Emile Georges Guillemont, Mikaël Paugam, Bruno Francois Marie Delest, Jan Heeres, Paulus Joannes Lewi, Paul Adriaan Jan Janssen, Frank Xavier Jozef Herwig Arts, legal representative
  • Patent number: 7986401
    Abstract: Methods and apparatus to determine the orientation of randomly arranged birefringent fibers are disclosed. One method comprises emitting light, creating Ni polarization states of the emitted light, illuminating the birefringent fibers with the emitted light so polarized, thereby generating IRi internal reflection components of the light in the birefringent fibers, observing the light from the illuminated birefringent fibers, creating Oi polarization states of the observed light, forming Ii images of the observed polarized light, each image comprising an information (Ni, Oi, IRi), wherein i=1, 2, . . . , n and n?3, separating the i-th internal reflection component from the i-th image, and calculating an angle of a neutral axis of the birefringent fibers using the IRi internal reflection components.
    Type: Grant
    Filed: September 25, 2009
    Date of Patent: July 26, 2011
    Assignee: Bossa Nova Technologies, LLC
    Inventors: Nicolas Lechocinski, Sebastien Breugnot, Bruno Francois Pouet
  • Patent number: 7978341
    Abstract: A multi-channel laser interferometric method and apparatus are provided for optically measuring transient motion from a surface (17). A laser beam (11) is generated and then divided into first and second beams having respective intensities representing minor and major fraction of the predetermined laser intensity. The reference beam (18) illuminates the surface (17) at which deformation is expected. The light back-scattered by the surface is collected by a single aperture lens (15) and then made to interfere with the probe beam (67) which has been expanded (32), onto a two-dimensional array of detectors (71). Each signal (83) corresponding to each detector of the array is converted individually to an electrical signal, each electrical signal is amplified and processed (84), and the plurality of processed signals (85) is then averaged in an electrical summing means (45).
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: July 12, 2011
    Assignee: Bossa Nova Technologies, LLC
    Inventor: Bruno Francois Pouet
  • Publication number: 20110075144
    Abstract: Methods and apparatus to measure visual appearance of randomly arranged birefringent fibers are disclosed. One method comprises emitting light, creating Ni polarization states of the emitted light, illuminating the birefringent fibers with the emitted light so polarized, thereby generating IRi internal reflection components, ERi external reflection components, and Di diffusion components of the light in the birefringent fibers, observing the light from the illuminated birefringent fibers, creating Oi polarization states of the observed light, forming Xi images of the observed polarized light, each image comprising an information (Ni, Oi, IRi, ERi, Di), wherein i=1, 2, . . . n and n?4, measuring the intensity Ii in each pixel in the X, images, and separating the i-th internal reflection component, the i-th external reflection component, and the i-th diffusion component from the i-th image for the Xi images.
    Type: Application
    Filed: September 25, 2009
    Publication date: March 31, 2011
    Applicants: BOSSA NOVA TECHNOLOGIES, LLC
    Inventors: Nicolas Lechocinski, Sebastien Breugnot, Bruno Francois Pouet
  • Publication number: 20110075128
    Abstract: Methods and apparatus to determine the orientation of randomly arranged birefringent fibers are disclosed. One method comprises emitting light, creating Ni polarization states of the emitted light, illuminating the birefringent fibers with the emitted light so polarized, thereby generating IRi internal reflection components of the light in the birefringent fibers, observing the light from the illuminated birefringent fibers, creating Oi polarization states of the observed light, forming Ii images of the observed polarized light, each image comprising an information (Ni, Oi, IRi), wherein i=1, 2, . . . , n and n?3, separating the i-th internal reflection component from the i-th image, and calculating an angle of a neutral axis of the birefringent fibers using the IRi internal reflection components.
    Type: Application
    Filed: September 25, 2009
    Publication date: March 31, 2011
    Applicant: BOSSA NOVA TECHNOLOGIES, LLC
    Inventors: Nicolas Lechocinski, Sebastien Breugnot, Bruno Francois Pouet
  • Publication number: 20110074946
    Abstract: Methods and apparatus to measure visual appearance of birefringent fibers are disclosed. One method comprises emitting light, creating Ni polarization states of the emitted light, illuminating the birefringent fibers with the emitted light so polarized, thereby generating IRi internal reflection components, ERi external reflection components, and Di diffusion components of the light in the birefringent fibers, observing the light from the illuminated birefringent fibers, creating Oi polarization states of the observed light, forming Xi images of the observed polarized light, each image comprising an information (Ni, Oi, IRi, ERi, Di), wherein i=1, 2, . . . n and n?4, measuring the intensity Ii in each pixel in the Xi images, and separating the i-th internal reflection component, the i-th external reflection component, and the i-th diffusion component from the i-th image for the Xi images.
    Type: Application
    Filed: March 18, 2010
    Publication date: March 31, 2011
    Applicants: BOSSA NOVA TECHNOLOGIES, LLC, The Proctor & Gamble Company
    Inventors: Nicolas Lechocinski, Sebastien Breugnot, Bruno Francois Pouet
  • Patent number: 7864338
    Abstract: An apparatus and a method for detecting surface motion of an object subject to ultrasound are disclosed. The method comprises generating a laser beam, dividing the laser beam into a reference beam and an object beam to be directed onto the surface, thereby producing a scattered object beam, introducing a frequency shift between the reference beam and the scattered object beam, wherein the frequency shift is smaller than the ultrasonic frequency, detecting the interference between the scattered object beam and the frequency shifted reference beam using a plurality of detecting elements to generate a plurality of electrical interference signals, wherein the electrical interference signals each comprise a wanted signal component indicative of the surface motion and a noise signal component, and processing the electrical interference signals to determine the surface motion of the object.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: January 4, 2011
    Assignee: Bossa Nova Technologies, LLC
    Inventor: Bruno Francois Pouet
  • Publication number: 20100205333
    Abstract: The invention generally pertains to onboard systems for passengers such as In-Flight Entertainment (IFE) Systems. The invention more particularly relates to a system and a method for accessing a personal computer device (3) onboard an aircraft and to an aircraft including such a system. The system includes an onboard network (12) to which is connected at least one interface (4) at a passenger's seat (si) and connection means. The system is arranged so that said interface and said personal computer device interact via the transmission of data on said onboard network.
    Type: Application
    Filed: September 19, 2008
    Publication date: August 12, 2010
    Applicant: AIRBUS SAS
    Inventors: Bruno Francois, Garrett Smith
  • Publication number: 20100168104
    Abstract: This invention concerns pyrimidine derivatives of formula having HIV (Human Immunodeficiency Virus) replication inhibiting properties, the preparation thereof and pharmaceutical compositions comprising these compounds.
    Type: Application
    Filed: March 30, 2007
    Publication date: July 1, 2010
    Inventors: Jerôme Emile Georges Guillemont, Mikaël Paugam, Bruno François Marie Delest
  • Patent number: 7729881
    Abstract: A laser interferometric apparatus for measuring a displacement of an object is disclosed, the apparatus comprising a laser source for producing a laser beam having a given intensity, a beam splitter for dividing the laser beam into a reference beam and an object beam to be directed to the object, thereby producing a scattered object beam being modulated according to the displacement of the object, interference means adapted to provide at least two electrical interference signals from the scattered object beam and the reference beam, the at least two electrical interference signals each comprising a wanted signal component indicative of the object displacement and an intensity noise component, and processing means for subtracting the at least two electrical interference signals, thereby generating an output signal, the output signal comprising substantially the wanted signal component alone, wherein the intensity noise is substantially rejected.
    Type: Grant
    Filed: January 8, 2008
    Date of Patent: June 1, 2010
    Assignee: Bossa Nova Technologies, LLC
    Inventor: Bruno Francois Pouet