Abstract: Disclosed herein are novel biomarkers for identifying patients, with cancer, likely to benefit from treatment with an anti-CD25 agent. Also disclosed are methods using said biomarkers for making a treatment decision—or monitoring treatment with an anti-CD25 agent as well as methods of treating a patient, with cancer, comprising administering an anti-CD25 agent based on prior use of the present biomarkers.

Abstract: The present invention describes capsule compositions consisting of crosslinked chitosan, beta-glucan or alginate, and encapsulates an environmentally compatible insecticide, especially larvicidal agents such as essential oils or essential oil components or other ingestible larvicides such as Bacillus thuringiensis which are lethal to the larvae and adults of pest insects, especially mosquito larvae.

Abstract: The present invention refers to a device with diametral magnetic arrays for installations in magnetic SUBs, aiming the remediation and mitigation of inorganic and organic scales in production columns. The proposed magnetic device meets several specific criteria based on the magnetohydrodynamic model (MHD). After applying the said device with the proposed magnetic field, an efficiency of the scale inhibition was experimentally observed through laboratory tests, obtained from the values of the masses encrusted in the walls of the experimental bench system in the laboratory, with respect to the application without magnetic field. The device described herein can be installed in any pipeline used to transport fluids, including underwater pipelines for oil wells. These fluids can be oils, lubricants, gases, steams, water, petroleum or liquids in general.

Abstract: The present invention describes capsule compositions consisting of crosslinked chitosan, beta-glucan or alginate, and encapsulates an environmentally compatible ingestible larvicide, especially larvicidal agents such as essential oils or other ingestible larvicides such as Bacillus thuringiensis which are lethal to the larvae of pest insects, especially mosquito larvae.

Abstract: Provided herein, in some embodiments, are recombinantly engineered variant of stefin polypeptides (AFFIMER® polypeptides) that binds to human serum albumin and extends the half-life of the polypeptides. Also provided herein, in some embodiments, are composition containing the polypeptides, methods of using the polypeptides, and methods of producing the polypeptides.

Abstract: The present invention relates to compounds of Formula I or pharmaceutically acceptable salts or solvates thereof. The invention further relates to the use of the compounds of Formula I as A2A inhibitors. The invention also relates to the use of the compounds of Formula I for the treatment and/or prevention of cancer. The invention also relates to a process for manufacturing compounds of Formula I.

Abstract: Improved techniques to access content from documents in an automated fashion. The improved techniques permit content of tables within documents to be retrieved and then used by computer systems operating various software programs (e.g., application programs). Consequently, Robotic Process Automation (RPA) systems are able to accurately understand the content of tables within documents so that users, application programs and/or software robots can operate on the documents with increased reliability and flexibility. The documents being received and processed can be electronic images of documents. For example, the documents can be business transaction documents which include tables, such as purchase orders, invoices, delivery receipts, bills of lading, etc.

Abstract: Improved techniques to access content from documents in an automated fashion. The improved techniques permit content within documents to be retrieved and then used by computer systems operating various software programs (e.g., application programs), such as an extraction program. Documents, especially business transaction documents, often have various descriptors (or tables) and values that form key-value pairs. The improved techniques permit key-value pairs within documents to be recognized and extracted from documents. Consequently, RPA systems are able to accurately understand the content of tables within documents so that users and/or software robots can operate on the documents with increased reliability and flexibility.

Abstract: Improved techniques to access content from documents in an automated fashion. The improved techniques permit extraction of data from documents, namely, images of documents. The extraction processing can be hierarchical, such as being performed in multiple levels (i.e., multi-leveled). At an upper level, numerous different objects within a document can be detected along with positional data for the objects and can be categorized based on a type of object. Then, at lower levels, the different objects can be processed differently depending on the type of object. As a result, data extraction from the document can be performed with greater reliability and precision.

Abstract: The present invention relates to compounds of Formula I or pharmaceutically acceptable salts or solvates thereof. The invention further relates to the use of the compounds of Formula I as A2A inhibitors. The invention also relates to the use of the compounds of Formula I for the treatment and/or prevention of cancer. The invention also relates to a process for manufacturing compounds of Formula I.

Abstract: The present invention relates to compounds of Formula I or pharmaceutically acceptable salts or solvates thereof. The invention further relates to the use of the compounds of Formula I as A2A inhibitors. The invention also relates to the use of the compounds of Formula I for the treatment and/or prevention of cancer. The invention also relates to a process for manufacturing compounds of Formula I.

Abstract: The present invention relates to compounds of Formula I or pharmaceutically acceptable salts or solvates thereof. The invention further relates to the use of the compounds of Formula I as A2A inhibitors. The invention also relates to the use of the compounds of Formula I for the treatment and/or prevention of cancer. The invention also relates to a process for manufacturing compounds of Formula I.

Abstract: The present invention relates to a compound with the following formula: formula (I) or a salt and/or a pharmaceutically acceptable solvate thereof, in particular for use as a drug, in particular in the treatment of cancer, as well as to the pharmaceutical compositions that contain same and to the methods for preparing same.