Abstract: Disclosed herein are novel biomarkers for identifying patients, with cancer, likely to benefit from treatment with an anti-CD25 agent. Also disclosed are methods using said biomarkers for making a treatment decision—or monitoring treatment with an anti-CD25 agent as well as methods of treating a patient, with cancer, comprising administering an anti-CD25 agent based on prior use of the present biomarkers.

Abstract: The present invention refers to a device with diametral magnetic arrays for installations in magnetic SUBs, aiming the remediation and mitigation of inorganic and organic scales in production columns. The proposed magnetic device meets several specific criteria based on the magnetohydrodynamic model (MHD). After applying the said device with the proposed magnetic field, an efficiency of the scale inhibition was experimentally observed through laboratory tests, obtained from the values of the masses encrusted in the walls of the experimental bench system in the laboratory, with respect to the application without magnetic field. The device described herein can be installed in any pipeline used to transport fluids, including underwater pipelines for oil wells. These fluids can be oils, lubricants, gases, steams, water, petroleum or liquids in general.

Abstract: The present invention relates to a compound with the following formula: formula (I) or a salt and/or a pharmaceutically acceptable solvate thereof, in particular for use as a drug, in particular in the treatment of cancer, as well as to the pharmaceutical compositions that contain same and to the methods for preparing same.