Patents by Inventor Bruno Kaesler
Bruno Kaesler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11419811Abstract: The present invention relates to a microorganism belonging to the group of lactic acid bacteria characterized in that it is capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; and/or (ii) resistant to protease treatment; and/or (iii) calcium-dependent; and/or (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. Preferably, the specific binding can be assayed as follows: (a) growing said microorganism to stationary phase; (b) mixing said microorganism with Streptococcus mutans which has been grown to stationary phase; (c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and Streptococcus mutans and (d) detecting aggregates by the occurrence of a pellet.Type: GrantFiled: September 24, 2019Date of Patent: August 23, 2022Inventors: Bruno Kaesler, Rolf Knöll, Mewes Boettner, Eckhard Budde, Christine Lang, Martin Ryser, Markus Veen
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Publication number: 20200085727Abstract: The present invention relates to a microorganism belonging to the group of lactic acid bacteria characterized in that it is capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; and/or (ii) resistant to protease treatment; and/or (iii) calcium-dependent; and/or (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. Preferably, the specific binding can be assayed as follows: (a) growing said microorganism to stationary phase; (b) mixing said microorganism with Streptococcus mutans which has been grown to stationary phase; (c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and Streptococcus mutans and (d) detecting aggregates by the occurrence of a pellet.Type: ApplicationFiled: September 24, 2019Publication date: March 19, 2020Inventors: BRUNO KAESLER, Rolf KNÖLL, Mewes BOETTNER, Eckhard BUDDE, Christine LANG, Martin RYSER, Markus VEEN
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Publication number: 20170258708Abstract: The present invention relates to a microorganism belonging to the group of lactic acid bacteria characterized in that it is capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; and/or (ii) resistant to protease treatment; and/or (iii) calcium-dependent; and/or (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. Preferably, the specific binding can be assayed as follows: (a) growing said microorganism to stationary phase; (b) mixing said microorganism with Streptococcus mutans which has been grown to stationary phase; (c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and Streptococcus mutans and (d) detecting aggregates by the occurrence of a pellet.Type: ApplicationFiled: May 23, 2017Publication date: September 14, 2017Inventors: Bruno KAESLER, Rolf Knöll, Mewes Boettner, Eckhard Budde, Christine Lang, Martin Ryser, Markus Veen
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Publication number: 20120237454Abstract: The present invention relates to a microorganism belonging to the group of lactic acid bacteria capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; (ii) resistant to protease treatment; (iii) calcium-dependent; (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. The present invention is also relates to an analog or fragment of the microorganism which is thermally inactivated or lyophilized, wherein the analog or fragment retains the capability of specifically binding to Streptococcus mutans. The invention further encompasses compositions and additives for food, feed or drinks comprising the microorganism or an analog or fragment thereof. Also provided is uses of the microorganism or an analog or fragment thereof for the preparation of an anticariogenic or pharmaceutical composition or anticariogenic food or feedstuff as well as methods for producing the compositions or food or feedstuff.Type: ApplicationFiled: May 2, 2012Publication date: September 20, 2012Applicant: BASF AktiengesellschaftInventors: Bruno Kaesler, Rolf Knöll, Mewes Boettner, Eckhard Budde, Christine Lang, Martin Ryser, Markus Veen
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Patent number: 8192978Abstract: The present invention relates to a microorganism belonging to the group of lactic acid bacteria characterized in that it is capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; and/or (ii) resistant to protease treatment; and/or (iii) calcium-dependent; and/or (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. Preferably, the specific binding can be assayed as follows: (a) growing said microorganism to stationary phase; (b) mixing said microorganism with Streptococcus mutans which has been grown to stationary phase; (c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and Streptococcus mutans and (d) detecting aggregates by the occurrence of a pellet.Type: GrantFiled: September 9, 2005Date of Patent: June 5, 2012Assignee: BASF AktiengesellschaftInventors: Bruno Kaesler, Rolf Knöll, Mewes Boettner, Eckhard Budde, Christine Lang, Martin Ryser, Markus Veen
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Patent number: 7691596Abstract: The present invention relates to methods for determining GTP Cyclohydrolase I or II activity in a sample.Type: GrantFiled: September 5, 2008Date of Patent: April 6, 2010Assignee: BASF SEInventors: Annette Freund, Franz Röhl, Henning Althöfer, Marvin Karos, Bruno Kaesler, Thierry Lacour
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Publication number: 20090023172Abstract: The present invention relates to the identification of fungal GTP cyclohydrolase II as a target for fungicides, to a method for identifying antifungal agents based on fungal GTP cyclohydrolase II, and also to the use of compounds identified as fungicides via the abovementioned method.Type: ApplicationFiled: September 5, 2008Publication date: January 22, 2009Inventors: Annette FREUND, Franz Rohl, Henning Althofer, Marvin Karos, Bruno Kaesler, Thierry Lacour
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Patent number: 7435557Abstract: The present invention relates to the identification of fungal GTP cyclohydrolase II as a target for fungicides, to a method for identifying antifungal agents based on fungal GTP cyclohydrolase II, and also to the use of compounds identified as fungicides via the abovementioned method.Type: GrantFiled: June 29, 2006Date of Patent: October 14, 2008Assignee: BASF AktiengesellschaftInventors: Annette Freund, Franz Röhl, Henning Althöfer, Marvin Karos, Bruno Kaesler, Thierry Lacour
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Publication number: 20080193427Abstract: The present invention relates to a microorganism belonging to the group of lactic acid bacteria characterized in that it is capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; and/or (ii) resistant to protease treatment; and/or (iii) calcium-dependent; and/or (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. Preferably, the specific binding can be assayed as follows: (a) growing said microorganism to stationary phase; (b) mixing said microorganism with Streptococcus mutans which has been grown to stationary phase; (c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and Streptococcus mutans and (d) detecting aggregates by the occurrence of a pellet.Type: ApplicationFiled: September 9, 2005Publication date: August 14, 2008Applicant: BASF AktiengesellschaftInventors: Bruno Kaesler, Rolf Knoll, Mewes Boettner, Eckhard Budde, Christine Lang, Martin Ryser, Markus Veen
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Patent number: 7223543Abstract: The present invention relates to a process for the production of conjugated linoleic acid and a process for the production of triglycerides with an increased content of conjugated linoleic acid. Moreover, the invention relates to a nucleic acid sequence; a nucleic acid construct, a vector and transgenic organisms comprising at least one nucleic acid sequence or one nucleic acid construct which encodes a polypeptide with conjugated linoleic isomerase activity. Furthermore, the invention relates to the use of a microorganism of the genus Bifidobacterium as a probiotic.Type: GrantFiled: June 10, 2002Date of Patent: May 29, 2007Assignee: Teagasc Dairy Products Research CentreInventors: Catherine Stanton, R. Paul Ross, Oskar Zelder, Bruno Kaesler
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Publication number: 20060240502Abstract: The present invention relates to the identification of fungal GTP cyclohydrolase II as a target for fungicides, to a method for identifying antifungal agents based on fungal GTP cyclohydrolase II, and also to the use of compounds identified as fungicides via the abovementioned method.Type: ApplicationFiled: June 29, 2006Publication date: October 26, 2006Inventors: Annette Freund, Franz Rohl, Henning Althofer, Marvin Karos, Bruno Kaesler, Thierry Lacour
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Patent number: 7037708Abstract: Dry microorganism cultures comprising at least one microorganism species in carrier-bound form are present in the form of particles which a) have a particle size of at least about 0.1 mm and b) are compressed; processes for preparing dry microorganism cultures and their use for preparing foodstuffs and feedstuffs are also claimed.Type: GrantFiled: April 29, 1999Date of Patent: May 2, 2006Assignee: BASF AktiengesellschaftInventors: Frank Runge, Bryan Cooper, Ulrich Bröckel, Robert Heinz, Hans-Peter Harz, Ulrich Eidelsburger, Bruno Käsler, Thomas Keller
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Publication number: 20050239159Abstract: The present invention relates to the identification of fungal GTP cyclohydrolase II as a target for fungicides, to a method for identifying antifungal agents based on fungal GTP cyclohydrolase II, and also to the use of compounds identified as fungicides via the abovementioned method.Type: ApplicationFiled: August 23, 2003Publication date: October 27, 2005Inventors: Annette Freund, Franz Rohl, Henning Althofer, Marvin Karos, Bruno Kaesler, Thierry Lacour
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Publication number: 20050240085Abstract: A method includes obtaining subjective and objective inputs from an individual in need of a custom prepared composition for changing or improving one or more of the individual's conditions. Objective data may be collected by analyzing one or more samples taken from the individual. Subjective data may include data provided in response to a questionnaire by the individual. The objective and subjective inputs are compared against an empirically derived database which links certain affects to variables associated with the subjective and objective inputs.Type: ApplicationFiled: January 14, 2005Publication date: October 27, 2005Applicant: BASF AktiengesellschaftInventors: Rolf Knoell, Bruno Kaesler
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Publication number: 20050118208Abstract: The present invention relates to pulverulent formulations comprising at least one conjugated trans/-cis-octadecapolyenoic acid and also production and use thereof for use in foods, food supplements, feedstuffs, feed additives, pharmaceutical and cosmetic preparations.Type: ApplicationFiled: November 27, 2002Publication date: June 2, 2005Applicant: BASF AktiengesellschaftInventors: Wolfgang Bewert, Morton Mohr Hansen, Oliver Hasselwander, Ulrike Sindel, Arne Ptock, Willy Hinz, Angelika-Maria Pfeiffer, Andreas Habich, Bruno Kaesler
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Publication number: 20040197790Abstract: The present invention relates to a process for the production of conjugated linoleic acid and a process for the production of triglycerides with an increased content of conjugated linoleic acid. Moreover, the invention relates to a nucleic acid sequence; a nucleic acid construct, a vector and transgenic organisms comprising at least one nucleic acid sequence or one nucleic acid construct which encodes a polypeptide with conjugated linoleic isomerase activity. Furthermore, the invention relates to the use of a microorganism of the genus Bifidobacterium as a probiotic.Type: ApplicationFiled: December 5, 2003Publication date: October 7, 2004Inventors: Catherine Stanton, R Paul Ross, Oskar Zelder, Bruno Kaesler
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Patent number: 6183794Abstract: The disclosure is directed to a solution of 78.0-93.0% by weight propionic acid, 0.5-5.0% by weight ammonia, 1.0-6.0% by weight propanediol, 0.1-10.0% by weight water, where the amounts of individual components add up to 100% by weight, and its use in livestock nutrition.Type: GrantFiled: September 14, 1999Date of Patent: February 6, 2001Assignee: BASF AktiengesellschaftInventors: Bruno Kaesler, Hans Müschen, Harald Streicher, Wolfgang Samson