Patents by Inventor Bruno Kaesler

Bruno Kaesler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11419811
    Abstract: The present invention relates to a microorganism belonging to the group of lactic acid bacteria characterized in that it is capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; and/or (ii) resistant to protease treatment; and/or (iii) calcium-dependent; and/or (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. Preferably, the specific binding can be assayed as follows: (a) growing said microorganism to stationary phase; (b) mixing said microorganism with Streptococcus mutans which has been grown to stationary phase; (c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and Streptococcus mutans and (d) detecting aggregates by the occurrence of a pellet.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: August 23, 2022
    Inventors: Bruno Kaesler, Rolf Knöll, Mewes Boettner, Eckhard Budde, Christine Lang, Martin Ryser, Markus Veen
  • Publication number: 20200085727
    Abstract: The present invention relates to a microorganism belonging to the group of lactic acid bacteria characterized in that it is capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; and/or (ii) resistant to protease treatment; and/or (iii) calcium-dependent; and/or (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. Preferably, the specific binding can be assayed as follows: (a) growing said microorganism to stationary phase; (b) mixing said microorganism with Streptococcus mutans which has been grown to stationary phase; (c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and Streptococcus mutans and (d) detecting aggregates by the occurrence of a pellet.
    Type: Application
    Filed: September 24, 2019
    Publication date: March 19, 2020
    Inventors: BRUNO KAESLER, Rolf KNÖLL, Mewes BOETTNER, Eckhard BUDDE, Christine LANG, Martin RYSER, Markus VEEN
  • Publication number: 20170258708
    Abstract: The present invention relates to a microorganism belonging to the group of lactic acid bacteria characterized in that it is capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; and/or (ii) resistant to protease treatment; and/or (iii) calcium-dependent; and/or (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. Preferably, the specific binding can be assayed as follows: (a) growing said microorganism to stationary phase; (b) mixing said microorganism with Streptococcus mutans which has been grown to stationary phase; (c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and Streptococcus mutans and (d) detecting aggregates by the occurrence of a pellet.
    Type: Application
    Filed: May 23, 2017
    Publication date: September 14, 2017
    Inventors: Bruno KAESLER, Rolf Knöll, Mewes Boettner, Eckhard Budde, Christine Lang, Martin Ryser, Markus Veen
  • Publication number: 20120237454
    Abstract: The present invention relates to a microorganism belonging to the group of lactic acid bacteria capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; (ii) resistant to protease treatment; (iii) calcium-dependent; (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. The present invention is also relates to an analog or fragment of the microorganism which is thermally inactivated or lyophilized, wherein the analog or fragment retains the capability of specifically binding to Streptococcus mutans. The invention further encompasses compositions and additives for food, feed or drinks comprising the microorganism or an analog or fragment thereof. Also provided is uses of the microorganism or an analog or fragment thereof for the preparation of an anticariogenic or pharmaceutical composition or anticariogenic food or feedstuff as well as methods for producing the compositions or food or feedstuff.
    Type: Application
    Filed: May 2, 2012
    Publication date: September 20, 2012
    Applicant: BASF Aktiengesellschaft
    Inventors: Bruno Kaesler, Rolf Knöll, Mewes Boettner, Eckhard Budde, Christine Lang, Martin Ryser, Markus Veen
  • Patent number: 8192978
    Abstract: The present invention relates to a microorganism belonging to the group of lactic acid bacteria characterized in that it is capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; and/or (ii) resistant to protease treatment; and/or (iii) calcium-dependent; and/or (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. Preferably, the specific binding can be assayed as follows: (a) growing said microorganism to stationary phase; (b) mixing said microorganism with Streptococcus mutans which has been grown to stationary phase; (c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and Streptococcus mutans and (d) detecting aggregates by the occurrence of a pellet.
    Type: Grant
    Filed: September 9, 2005
    Date of Patent: June 5, 2012
    Assignee: BASF Aktiengesellschaft
    Inventors: Bruno Kaesler, Rolf Knöll, Mewes Boettner, Eckhard Budde, Christine Lang, Martin Ryser, Markus Veen
  • Patent number: 7691596
    Abstract: The present invention relates to methods for determining GTP Cyclohydrolase I or II activity in a sample.
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: April 6, 2010
    Assignee: BASF SE
    Inventors: Annette Freund, Franz Röhl, Henning Althöfer, Marvin Karos, Bruno Kaesler, Thierry Lacour
  • Publication number: 20090023172
    Abstract: The present invention relates to the identification of fungal GTP cyclohydrolase II as a target for fungicides, to a method for identifying antifungal agents based on fungal GTP cyclohydrolase II, and also to the use of compounds identified as fungicides via the abovementioned method.
    Type: Application
    Filed: September 5, 2008
    Publication date: January 22, 2009
    Inventors: Annette FREUND, Franz Rohl, Henning Althofer, Marvin Karos, Bruno Kaesler, Thierry Lacour
  • Patent number: 7435557
    Abstract: The present invention relates to the identification of fungal GTP cyclohydrolase II as a target for fungicides, to a method for identifying antifungal agents based on fungal GTP cyclohydrolase II, and also to the use of compounds identified as fungicides via the abovementioned method.
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: October 14, 2008
    Assignee: BASF Aktiengesellschaft
    Inventors: Annette Freund, Franz Röhl, Henning Althöfer, Marvin Karos, Bruno Kaesler, Thierry Lacour
  • Publication number: 20080193427
    Abstract: The present invention relates to a microorganism belonging to the group of lactic acid bacteria characterized in that it is capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; and/or (ii) resistant to protease treatment; and/or (iii) calcium-dependent; and/or (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. Preferably, the specific binding can be assayed as follows: (a) growing said microorganism to stationary phase; (b) mixing said microorganism with Streptococcus mutans which has been grown to stationary phase; (c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and Streptococcus mutans and (d) detecting aggregates by the occurrence of a pellet.
    Type: Application
    Filed: September 9, 2005
    Publication date: August 14, 2008
    Applicant: BASF Aktiengesellschaft
    Inventors: Bruno Kaesler, Rolf Knoll, Mewes Boettner, Eckhard Budde, Christine Lang, Martin Ryser, Markus Veen
  • Patent number: 7223543
    Abstract: The present invention relates to a process for the production of conjugated linoleic acid and a process for the production of triglycerides with an increased content of conjugated linoleic acid. Moreover, the invention relates to a nucleic acid sequence; a nucleic acid construct, a vector and transgenic organisms comprising at least one nucleic acid sequence or one nucleic acid construct which encodes a polypeptide with conjugated linoleic isomerase activity. Furthermore, the invention relates to the use of a microorganism of the genus Bifidobacterium as a probiotic.
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: May 29, 2007
    Assignee: Teagasc Dairy Products Research Centre
    Inventors: Catherine Stanton, R. Paul Ross, Oskar Zelder, Bruno Kaesler
  • Publication number: 20060240502
    Abstract: The present invention relates to the identification of fungal GTP cyclohydrolase II as a target for fungicides, to a method for identifying antifungal agents based on fungal GTP cyclohydrolase II, and also to the use of compounds identified as fungicides via the abovementioned method.
    Type: Application
    Filed: June 29, 2006
    Publication date: October 26, 2006
    Inventors: Annette Freund, Franz Rohl, Henning Althofer, Marvin Karos, Bruno Kaesler, Thierry Lacour
  • Patent number: 7037708
    Abstract: Dry microorganism cultures comprising at least one microorganism species in carrier-bound form are present in the form of particles which a) have a particle size of at least about 0.1 mm and b) are compressed; processes for preparing dry microorganism cultures and their use for preparing foodstuffs and feedstuffs are also claimed.
    Type: Grant
    Filed: April 29, 1999
    Date of Patent: May 2, 2006
    Assignee: BASF Aktiengesellschaft
    Inventors: Frank Runge, Bryan Cooper, Ulrich Bröckel, Robert Heinz, Hans-Peter Harz, Ulrich Eidelsburger, Bruno Käsler, Thomas Keller
  • Publication number: 20050239159
    Abstract: The present invention relates to the identification of fungal GTP cyclohydrolase II as a target for fungicides, to a method for identifying antifungal agents based on fungal GTP cyclohydrolase II, and also to the use of compounds identified as fungicides via the abovementioned method.
    Type: Application
    Filed: August 23, 2003
    Publication date: October 27, 2005
    Inventors: Annette Freund, Franz Rohl, Henning Althofer, Marvin Karos, Bruno Kaesler, Thierry Lacour
  • Publication number: 20050240085
    Abstract: A method includes obtaining subjective and objective inputs from an individual in need of a custom prepared composition for changing or improving one or more of the individual's conditions. Objective data may be collected by analyzing one or more samples taken from the individual. Subjective data may include data provided in response to a questionnaire by the individual. The objective and subjective inputs are compared against an empirically derived database which links certain affects to variables associated with the subjective and objective inputs.
    Type: Application
    Filed: January 14, 2005
    Publication date: October 27, 2005
    Applicant: BASF Aktiengesellschaft
    Inventors: Rolf Knoell, Bruno Kaesler
  • Publication number: 20050118208
    Abstract: The present invention relates to pulverulent formulations comprising at least one conjugated trans/-cis-octadecapolyenoic acid and also production and use thereof for use in foods, food supplements, feedstuffs, feed additives, pharmaceutical and cosmetic preparations.
    Type: Application
    Filed: November 27, 2002
    Publication date: June 2, 2005
    Applicant: BASF Aktiengesellschaft
    Inventors: Wolfgang Bewert, Morton Mohr Hansen, Oliver Hasselwander, Ulrike Sindel, Arne Ptock, Willy Hinz, Angelika-Maria Pfeiffer, Andreas Habich, Bruno Kaesler
  • Publication number: 20040197790
    Abstract: The present invention relates to a process for the production of conjugated linoleic acid and a process for the production of triglycerides with an increased content of conjugated linoleic acid. Moreover, the invention relates to a nucleic acid sequence; a nucleic acid construct, a vector and transgenic organisms comprising at least one nucleic acid sequence or one nucleic acid construct which encodes a polypeptide with conjugated linoleic isomerase activity. Furthermore, the invention relates to the use of a microorganism of the genus Bifidobacterium as a probiotic.
    Type: Application
    Filed: December 5, 2003
    Publication date: October 7, 2004
    Inventors: Catherine Stanton, R Paul Ross, Oskar Zelder, Bruno Kaesler
  • Patent number: 6183794
    Abstract: The disclosure is directed to a solution of 78.0-93.0% by weight propionic acid, 0.5-5.0% by weight ammonia, 1.0-6.0% by weight propanediol, 0.1-10.0% by weight water, where the amounts of individual components add up to 100% by weight, and its use in livestock nutrition.
    Type: Grant
    Filed: September 14, 1999
    Date of Patent: February 6, 2001
    Assignee: BASF Aktiengesellschaft
    Inventors: Bruno Kaesler, Hans Müschen, Harald Streicher, Wolfgang Samson