Patents by Inventor Bruno Lumachi

Bruno Lumachi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5212316
    Abstract: Compounds of formula I ##STR1## wherein Ar is an optionally substituted phenyl ring; B is a single bond, a group --(CH.sub.2 OCH.sub.2).sub.n being n=or 2, a a 2,4-disubstituted-1,3-dioxolane ring or a 2,4-disubstituted-1,3-thioxolane ring, R is a single bond, an optionally substituted methylene or ethylene group and T is 2, 3- or 4-pyridyl, an optionally salified or esterified carboxy group or a carboxyamide group. Said compounds are useful in treatment of respiratory diseases.
    Type: Grant
    Filed: July 30, 1990
    Date of Patent: May 18, 1993
    Assignee: Boehringer Mannheim Italia
    Inventors: Silvano Spinelli, Roberto Di Domenico, Ernesto Menta, Bruno Lumachi, Licia Gallico, Sergio Tognella
  • Patent number: 5206254
    Abstract: This application relates to compounds of formula I; ##STR1## wherein R is hydrogen, a linear or branched C.sub.1 -C.sub.4 -alkyl, allyl or propargyl; X is O, CH.sub.2 or S; R.sub.1 is --(CH.sub.2).sub.n Ra, hydroxy, --O--(CH.sub.2).sub.n Ra, --NRbRc or --NH c(CH.sub.2).sub.m --NRbRc; Ra is hydrogen, a linear or branched C.sub.1 -CH.sub.4 -alkyl, phenyl, p-methoxy-phenyl, 3,4,5-trimethoxyphenyl, B-pyryidyl, cyclopentyl or cyclohexyl; Rb and Rc, can be the same or different and are selected independently in the group of hydrogen, linear or branched C.sub.1 -C.sub.4 -alkyl, cyclohexyl, cyclopentyl, benzyl, hexahydrobenzyl, .alpha.,.beta. or .gamma.-pyridylmethyl; or Rb and Rc taken together with the N atom to which they are bound can form a morpholino, piperidino or piperazino residue of formula Rd--N(CH.sub.2 --CH.sub.2).sub.2 --N-- wherein Rd is hydrogen, linear or branched C.sub.1 -C.sub.4 -alkyl, benzyl, hexahydrobenzyl, (C.sub.6 H.sub.5).sub.2 CH--, (p--F--C.sub.6 H.sub.4).sub.
    Type: Grant
    Filed: October 29, 1990
    Date of Patent: April 27, 1993
    Assignee: Boehringer Mannheim Italia S.p.A.
    Inventors: Carmelo A. Gandolfi, Roberto Di Domenico, Silvano Spinelli, Licia Gallico, Bruno Lumachi, Sergio Tognella
  • Patent number: 4988701
    Abstract: Cyclic amino-thioacetal amides of formula I ##STR1## wherein X is O, S, p is 1 or 2, R and R.sub.1 are optionally esterified hydrogen or carboxy, A is a single bond, methylene or ethylene, m is zero or 1, n is an integer 1 to 7 and y is a imidazole or .beta.-pyridylmethyl residue.Compounds I have valuable therapeutic properties.
    Type: Grant
    Filed: December 15, 1989
    Date of Patent: January 29, 1991
    Assignee: Boehringer Biochemia Robin S.p.A.
    Inventors: Roberto Di Domenico, Carmelo A. Gandolfi, Silvano Spinelli, Bruno Lumachi, Odoardo Tofanetti, Sergio Tognella
  • Patent number: 4968706
    Abstract: Compounds of formula I ##STR1## wherein Ar is an optionally substituted phenyl ring; B is a single bond, a group --(CH.sub.2 OCH.sub.2).sub.n being n=1 or 2, a 2,4-disubstituted-1,3-dioxolane ring or a 2,4-disubstituted-1,3-thioxolane ring, R is a single bond, an optionally substituted methylene or ethylene group and T is 2-, 3- or 4-pyridyl, an optionally salified or esterified carboxy group or a carboxyamide group. Said compounds are useful in treatment of respiratory diseases.
    Type: Grant
    Filed: August 11, 1988
    Date of Patent: November 6, 1990
    Assignee: Boehringer Mannhein Italia, S.p.A.
    Inventors: Silvano Spinelli, Roberto Di Domenico, Ernesto Menta, Bruno Lumachi, Licia Gallico, Sergio Tognella