Patents by Inventor Bruno Madore
Bruno Madore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11744558Abstract: A system and method is provided for controlling against artifacts in medical imaging. The system includes an array of ultrasound sensors, each ultrasound sensor in the array of ultrasound sensors located at a variety of different spatial locations on a subject being imaged by an imaging system configured to generate medical imaging data and each ultrasound sensor configured to receive ultrasound sensor data. The system also includes a processor configured to receive the ultrasound sensor data from the array of ultrasound sensors, multiplex the ultrasound sensor data, generate anatomical information from the multiplexed ultrasound sensor data and correlated to the imaging system, and deliver the anatomical information to the imaging system in a form for use by the imaging system to either acquire the imaging data using the anatomical information or reconstruct the imaging data using the anatomical information.Type: GrantFiled: March 31, 2018Date of Patent: September 5, 2023Assignee: THE BRIGHAM AND WOMEN'S HOSPITALInventors: Bruno Madore, Frank R. Preiswerk
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Publication number: 20200113546Abstract: A system and method is provided for controlling against artifacts in medical imaging. The system includes an array of ultrasound sensors, each ultrasound sensor in the array of ultrasound sensors located at a variety of different spatial locations on a subject being imaged by an imaging system configured to generate medical imaging data and each ultrasound sensor configured to receive ultrasound sensor data. The system also includes a processor configured to receive the ultrasound sensor data from the array of ultrasound sensors, multiplex the ultrasound sensor data, generate anatomical information from the multiplexed ultrasound sensor data and correlated to the imaging system, and deliver the anatomical information to the imaging system in a form for use by the imaging system to either acquire the imaging data using the anatomical information or reconstruct the imaging data using the anatomical information.Type: ApplicationFiled: March 31, 2018Publication date: April 16, 2020Inventors: Bruno Madore, Frank R. Preiswerk
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Publication number: 20170172453Abstract: A system and method for quantitative imaging using a magnetic resonance imaging (MRI) system is disclosed. The method includes generating a steady-state pulse sequence on the MRI system, performing the pulse sequence to acquire magnetic resonance (MR) signals from a volume of the subject with two or more scans, representing physical parameters of the subject in relation with the MR signals through equations, generating values of the physical parameters of the subject, and generating a report indicating the physical parameters. The pulse sequence can sample two or more magnetization pathways of MR signals and at least one scan parameter of the pulse sequence changes from scan to scan.Type: ApplicationFiled: March 31, 2015Publication date: June 22, 2017Inventors: BRUNO MADORE, Cheng-chieh CHENG
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Publication number: 20150265250Abstract: A system and method for reconstructing ultrasound images provides improvements in image quality by using and digitally processing the acquired data along a plurality of dimensions. The echo signal reflected off different features in the object is reconstructed into images by solving a regularized linear system of equations that involves the geometry of the imaging transducer and of the image field-of-view. Processing can be performed ahead of time to create reconstruction matrices that can be reused indefinitely for a given transducer and field-of-view. The present invention can include a temporal encoding and decoding scheme, which includes changes in the direction of propagation and/or focusing characteris-tics of the transmitted ultrasound field from one time frame to the next, to provide improved discrimination between desired object features and artifacts.Type: ApplicationFiled: January 18, 2013Publication date: September 24, 2015Inventor: Bruno Madore
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Publication number: 20130006096Abstract: Embodiments of the present invention relate to systems and methods for magnetic resonance imaging (MRI) and, more particularly, to cardiac cine MRI in which the cardiac sequences are gated retrospectively. In some embodiments, UNFOLD or related temporally- based imaging (e.g., UNFOLD-SENSE) is combined with retrospective gating to produce, for example, better images of the heart in the late diastolic part of the cardiac cycle.Type: ApplicationFiled: December 10, 2007Publication date: January 3, 2013Inventor: Bruno Madore
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Patent number: 8330461Abstract: Embodiments of the present invention relate to accelerated dynamic magnetic resonance imaging (MRI) and, more particularly, to imaging situations where the temporal-encoding strategy is disrupted by time-related events, such as breathing motion.Type: GrantFiled: December 10, 2007Date of Patent: December 11, 2012Assignee: The Brigham and Women's Hospital, Inc.Inventor: Bruno Madore
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Patent number: 8235906Abstract: A system and method for performing accelerated ultrasound imaging provides significant increases in image acquisition speed using substantially simultaneous transmission of a plurality of ultrasound beams into an object being imaged. The resulting acquired echo signal contributions resulting from the reflection of the simultaneously transmitted beams off different features of the object being imaged are separated by employing a spatial decoding scheme. The spatial decoding scheme characterizes how received signals from features within the object being imaged are measured differently by each of the elements of an ultrasound transducer. The present invention may further include a temporal encoding and decoding scheme, which includes the modulation of a potion of the ultrasound beams transmitted during a portion of ultrasound data acquisition periods, to provide improved separation of the signal components from different features.Type: GrantFiled: December 30, 2008Date of Patent: August 7, 2012Assignee: The Brigham And Women's Hospital, Inc.Inventor: Bruno Madore
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Patent number: 8099148Abstract: A method for removing one or more artifacts from a time series of magnetic resonance (MR) images is provided. In one embodiment of the invention, an MR time series of data sets is acquired while changing the k-space that is sampled at each time frame. By using the acquired data, information is produced for a plurality of MR images at different time points, wherein the images contain desired components and one or more artifacts. Changing the k-space locations that are sampled from time frame to time frame makes the artifacts behave in a signature way through time, so that they can be identified as being artifacts and be removed through temporal analysis.Type: GrantFiled: October 15, 2007Date of Patent: January 17, 2012Assignee: Brigham and Women's Hospital, Inc.Inventor: Bruno Madore
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Publication number: 20100280381Abstract: A system and method for performing accelerated ultrasound imaging provides significant increases in image acquisition speed using substantially simultaneous transmission of a plurality of ultrasound beams into an object being imaged. The resulting acquired echo signal contributions resulting from the reflection of the simultaneously transmitted beams off different features of the object being imaged are separated by employing a spatial decoding scheme. The spatial decoding scheme characterizes how received signals from features within the object being imaged are measured differently by each of the elements of an ultrasound transducer. The present invention may further include a temporal encoding and decoding scheme, which includes the modulation of a potion of the ultrasound beams transmitted during a portion of ultrasound data acquisition periods, to provide improved separation of the signal components from different features.Type: ApplicationFiled: December 30, 2008Publication date: November 4, 2010Inventor: Bruno Madore
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Publication number: 20100117647Abstract: Embodiments of the present invention relate to accelerated dynamic magnetic resonance imaging (MRI) and, more particularly, to imaging situations where the temporal-encoding strategy is disrupted by time-related events, such as breathing motion.Type: ApplicationFiled: December 10, 2007Publication date: May 13, 2010Inventor: Bruno Madore
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Publication number: 20080205732Abstract: A method for removing one or more artifacts from a time series of magnetic resonance (MR) images is provided. In one embodiment of the invention, an MR time series of data sets is acquired while changing the k-space that is sampled at each time frame. By using the acquired data, information is produced for a plurality of MR images at different time points, wherein the images contain desired components and one or more artifacts. Changing the k-space locations that are sampled from time frame to time frame makes the artifacts behave in a signature way through time, so that they can be identified as being artifacts and be removed through temporal analysis.Type: ApplicationFiled: October 15, 2007Publication date: August 28, 2008Applicant: Brigham and Womens' Hospital, Inc.Inventor: Bruno Madore
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Patent number: 7283859Abstract: A method for removing one or more artifacts from a time series of magnetic resonance (MR) images is provided. In one embodiment of the invention, an MR time series of data sets is acquired while changing the k-space that is sampled at each time frame. By using the acquired data, information is produced for a plurality of MR images at different time points, wherein the images contain desired components and one or more artifacts. Changing the k-space locations that are sampled from time frame to time frame makes the artifacts behave in a signature way through time, so that they can be identified as being artifacts and be removed through temporal analysis.Type: GrantFiled: April 19, 2002Date of Patent: October 16, 2007Assignee: Brigham and Womens' Hospital, Inc.Inventor: Bruno Madore
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Patent number: 6903551Abstract: A variable density non-Cartesian parallel-imaging method for reconstructing a magnetic resonance (MR) image is provided. In embodiments of the invention, an MR data set is obtained by sampling first and second sampling regions, wherein a first region is sampled with a first sampling density that is higher than a second sampling density of a second region. MR images corrupted by aliasing artifacts are reconstructed from the data obtained with each one of the coil-elements of a coil array. These images can be combined into one, de-aliased image using a modified version of Cartesian SENSE. The modification allows all the available k-space lines to be used in the processing, despite the fact that different k-space regions have different sampling densities (i.e. non-Cartesian sampling). Using all available lines is advantageous in terms of signal-to-noise ratio.Type: GrantFiled: May 1, 2003Date of Patent: June 7, 2005Assignee: Brigham & Women's Hospital, Inc.Inventor: Bruno Madore
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Patent number: 6714010Abstract: A method for combining UNFOLD with a parallel magnetic resonance imaging (MRI) technique, such as SMASH, SENSE, or SPACE-RIP is provided. When acquiring only one nth of the usual amount of k-space data, data is acquired n times faster, but n signals will overlap in the resulting images. By spreading the n signals over all of the available temporal frequency bandwidth, UNFOLD reduces the amount of overlap to n/2. A parallel imaging method with an acceleration n/2 can finish the reconstruction by separating the n/2 overlapped signals. The result is a time series of non-corrupted images that are acquired n times faster than normal.Type: GrantFiled: April 19, 2002Date of Patent: March 30, 2004Assignee: Brigham and Women's Hospital, Inc.Inventor: Bruno Madore
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Publication number: 20030206016Abstract: A variable density non-Cartesian parallel-imaging method for reconstructing a magnetic resonance (MR) image is provided. In embodiments of the invention, an MR data set is obtained by sampling first and second sampling regions, wherein a first region is sampled with a first sampling density that is higher than a second sampling density of a second region. MR images corrupted by aliasing artifacts are reconstructed from the data obtained with each one of the coil-elements of a coil array. These images can be combined into one, de-aliased image using a modified version of Cartesian SENSE. The modification allows all the available k-space lines to be used in the processing, despite the fact that different k-space regions have different sampling densities (i.e. non-Cartesian sampling). Using all available lines is advantageous in terms of signal-to-noise ratio.Type: ApplicationFiled: May 1, 2003Publication date: November 6, 2003Inventor: Bruno Madore
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Publication number: 20020156364Abstract: A method for removing one or more artifacts from a time series of magnetic resonance (MR) images is provided. In one embodiment of the invention, an MR time series of data sets is acquired while changing the k-space that is sampled at each time frame. By using the acquired data, information is produced for a plurality of MR images at different time points, wherein the images contain desired components and one or more artifacts. Changing the k-space locations that are sampled from time frame to time frame makes the artifacts behave in a signature way through time, so that they can be identified as being artifacts and be removed through temporal analysis.Type: ApplicationFiled: April 19, 2002Publication date: October 24, 2002Inventor: Bruno Madore
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Publication number: 20020153890Abstract: A method for combining UNFOLD with a parallel magnetic resonance imaging (MRI) technique, such as SMASH, SENSE, or SPACE-RIP is provided. When acquiring only one nth of the usual amount of k-space data, data is acquired n times faster, but n signals will overlap in the resulting images. By spreading the n signals over all of the available temporal frequency bandwidth, UNFOLD reduces the amount of overlap to n/2. A parallel imaging method with an acceleration n/2 can finish the reconstruction by separating the n/2 overlapped signals. The result is a time series of non-corrupted images that are acquired n times faster than normal.Type: ApplicationFiled: April 19, 2002Publication date: October 24, 2002Inventor: Bruno Madore
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Patent number: 6353752Abstract: In some dynamic applications of MRI, only a part of the field-of-view (FOV) actually undergoes dynamic changes. A class of methods, called reduced-FOV (rFOV) methods, convert the knowledge that some part of the FOV is static or not very dynamic into an increase in temporal resolution for the dynamic part, or into a reduction in the scan time. Although cardiac imaging is an important example of an imaging situation where changes are concentrated into a fraction of the FOV, the rFOV methods developed up to now are not compatible with one of the most common cardiac sequences, the so-called retrospective cine method. The present work is a rFOV method designed to be compatible with cine imaging. An increase by a factor n in temporal resolution or a decrease by n in scan time is obtained in the case where only one nth of the FOV is dynamic (the rest being considered static). Results are presented for both Cartesian and spiral imaging.Type: GrantFiled: May 14, 1999Date of Patent: March 5, 2002Assignee: Board of Trustees of the Leland Standford Junior UniversityInventors: Bruno Madore, Norbert J. Pelc
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Patent number: 6144873Abstract: MRI is used to monitor the time behavior or an organ of interest. Images of such organ may change in time due to physiological motion, and/or due to contrast-agent accumulation. Dynamic applications generally involve acquiring data in a k-t space, which contains both temporal and spatial information. In some dynamic applications, the t axis of the k-t space is not densely filled with information. A method is introduced which can transfer information from the k axes to the t axis, allowing a denser, smaller k-t space to be acquired, and leading to significant reductions in the acquisition time of the temporal frames. Results are presented for cardiac imaging and functional MRI (fMRI). In the case of cardiac imaging, the present method is shown to reduce the data requirement by nearly a factor two. In the case of fMRI, reductions by as much as a factor six can be obtained. The behavior of the method is assessed by comparing the results to data obtained in a conventional way.Type: GrantFiled: April 17, 1998Date of Patent: November 7, 2000Assignee: Board of Trustees of The Leland Stanford Junior UniversityInventors: Bruno Madore, Gary H. Glover, Norbert J. Pelc
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Patent number: 5900731Abstract: A method is provided for use in constructing an MR image associated with the flow of blood or other fluid through an imaging volume, wherein material flowing through a selected voxel of the imaging volume is distinguished from static material. The method includes the step of applying a first MR pulse sequence to the imaging volume to produce a first MR data signal, having a magnitude which encodes first and second flow parameters for respective voxels comprising the volume, and having a phase which encodes a third flow parameter. The method further includes the step of applying a second MR pulse sequence to the volume, to produce a second MR data signal which indicates the content of respective voxels without flow encoding. The first and second MR data signals are compared to one another, such as by computing the difference therebetween, to determine the presence or absence of flowing material in respective voxels of the imaging volume.Type: GrantFiled: December 17, 1996Date of Patent: May 4, 1999Assignee: General Electric CompanyInventors: Ross Mark Henkelman, Bruno Madore