Patents by Inventor Bruno Perego

Bruno Perego has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dimethylamine benzoate or p-anisate catalysed process for the preparation of 4-(nitrophenyl)-dihydropyridines
    Patent number: 6015906
    Abstract: A method for the preparation of 4-(nitrophenyl)-dihydro-pyridines by reacting a benzaldehyde with an acetoacetate and reacting the resulting benzylidene derivative with an enamine derivative. Both reactions are catalyzed by dimethylamine benzoate or p-anisate.
    Type: Grant
    Filed: August 18, 1997
    Date of Patent: January 18, 2000
    Assignee: Lusochimica S.p.A.
    Inventors: Bruno Perego, Elso Manghisi
  • Process for the preparation of diltiazem
    Patent number: 5382663
    Abstract: (+)-Cis-3-(acetoxy)-5-[2-(dimethylamino)-ethyl]-2,3-dihydro-2-(4-methoxyphe nyl)-1,5-benzothiazepin-4(5H)-one hydrochloride is prepared by N-alkylation of (+)-cis-3-hydroxy-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H) -one with dimethylaminoethyl chloride and K.sub.2 CO.sub.3 in toluene/water, addition of a solubilizing agent and in the presence of a phase-transfer catalyst, the toluene phase being directly subjected to the final O-- acetylation.
    Type: Grant
    Filed: June 23, 1993
    Date of Patent: January 17, 1995
    Assignee: Lusochimica S.p.A.
    Inventors: Elso Manghisi, Bruno Perego