Abstract: The invention relates to cyclodextrin derivatives of formula (I): in which: R1=—NH-E-AA-(L1)p(L2)q where E=a linear or branched C1-C15 hydrocarbon-based group with, optionally, one or more hetero atoms; AA=the residue of an amino acid; L1 and L2=a C6-C24 hydrocarbon-based group with, optionally, one or more hetero atoms; p and q=0 or 1, at least one being ?0; R2=H, —CH3, isopropyl, hydroxypropyl, sulphobutyl ether; R3=H or R2, except when R2=hydroxypropyl; all the R4=—OH or R2, except when R2=hydroxypropyl, or at least one of the R4=R1; n=5, 6 or 7. The invention also relates to a process for preparing them, and to inclusion complexes and organized surfactant systems comprising them.

Abstract: The present invention relates to a per(3,6-anhydro)cyclodextrin derivative corresponding to one of the following formulae (I) or (II): in which: at least one of the values R1 represents a radical chosen from peptides, proteins, lipids, oligonucleotides or polynucleotides, oligosaccharides or polysaccharides, and biopolymers, and the other possible values R1, which may be identical or different, represent a group chosen from OH, OR3, OM, SH, SR3, OCOR3, NH2, NHR2,NR3R4, CONH2, CONHR3, CONR3R4, CN, COOR3, OCH2COOH, COOH, OSO2R3, N3 and R3, in which R3 and R4, which may be identical or different, represent a saturated or unsaturated, aliphatic or aromatic, hydrocarbon-based group optionally substituted with halogen atoms, which may contain one or more hetero atoms chosen from O, S and N, M represents a monovalent cation chosen from alkali metal cations; the values R2 represent a single bond or a spacer group, and n is equal to 6, 7 or 8.

Abstract: The invention relates to cyclodextrin derivatives of formula (I): in which: R1?—NH-E-AA-(L1)p(L2)q where E=a linear or branched Cl-Cl5 hydrocarbon-based group with, optionally, one or more hetero atoms; AA=the residue of an amino acid; L1 and L2=a C6-C24 hydrocarbon-based group with, optionally, one or more hetero atoms; p and q=0 or 1, at least one being ?0; R2?H, —CH3, isopropyl, hydroxypropyl, sulphobutyl ether; R3?H or R2, except when R2=hydroxypropyl; all the R4?—OH or R2, except when R2=hydroxypropyl, or at least one of the R4?R1; n=5, 6 or 7. The invention also relates to a process for preparing them, and to inclusion complexes and organized surfactant systems comprising them.

Abstract: The invention provides cyclodextrin derivatives that may be used to transport hydrophobic molecules for pharmaceutical or cosmetic applications, by forming organised systems in an aqueous medium, alone or with phospholipids. The cyclodextrin derivatives of the present invention have the formula: in which, R1 represents a steroid, R2 represents an alkyl or aryl group, substituted if applicable, R3 represents H or R2, all the R4 represent OR2, or one of the R4 represents —NHCO(CH2)mCONHR1, m is an integer ranging from 1 to 8, and n is equal to 5, 6 or 7.

Abstract: The invention concerns inclusion complexes of precursors from a natural source of organic isothiocyanates, in particular having bacteriostatic, bactericidal and/or fungicidal properties, in cyclodextrins. The isothiocyanate may meet the formula: R1—N═C═S  (I) in which R1 is for example the benzyl group. The precursor is a glucosinolate for example. The complex formed from a precursor may be converted into a complex of the corresponding isothiocyanate through enzymatic hydrolysis with myrosinase.

Abstract: The invention relates to the fixation or separation of ions, particularly of Pb, by per(3,6-anhydro)cylcodextrin derivatives. This can be carried out by contacting the medium containing the ions to be fixed or separated, with a per(3,6-anhydro)cylcodextrin derivative of formula: in which at least one of the R1 represents OCH3, whilst the other R1 can represent OCH3, OH or other groups, for complexing the ions. Preferably, for the fixation of lead, the derivative complies with formula (I) with n=6 and all the R1=OCH3.

Abstract: The invention relates to a process for the purification of water with a view to separating therefrom at least one organic substance, particularly olfactory pollutants such as (-)geosmine and (+)2-methyl-isoborneol.This process consists of contacting the water to be purified with a cyclodextrin of formula: ##STR1## in which R.sup.1 represents a hydrogen atom, a C.sub.1 to C.sub.12 alkyl group or the acetyl group CH.sub.3 CO--, R.sup.2 and R.sup.3, which can be the same or different, represent H or R.sup.1, and n=5, 6 or 7, in order to include therein the organic substance or substances to be separated and separating the purified water from the cyclodextrin.

Abstract: The invention relates to radio-pharmaceutical compositions that include an inclusion complex of a cyclodextrin and a radio-halogenated fatty acid.These complexes include a cyclodextrin such as .beta.-cyclodextrin, .gamma.-cyclodextrin and their derivatives, and a radio-halogenated fatty acid, in particular a fatty acid labelled with radioactive iodine such as 16-iodo 3-methyl hexadecanoic acid suitable for the examination of the myocardium by scintigraphy.The cyclodextrin allows the fatty acid to dissolve in aqueous solution without any addition of human blood albumin, while further improving the biodistribution of the fatty acid and its stability to heat.

Abstract: The invention relates to derivatives of cyclodextrins, their preparation and their use for incorporating hydrophobic molecules into organized surfactant systems. These derivatives of cyclodextrins are in accordance with the formula: ##STR1## in which R.sup.1 represents a group protecting an amine function, the R.sup.2, which can be the same or different, represent OH or NH--CH.sub.2 m--NHR.sup.1,m being an integer from 2 to 18 and n is equal to 5, 6 or 7.

Abstract: The invention relates to the use of natural cyclodextrins and their derivatives for the solubilization of platelet anti-aggregating agents from the family of Ginkgolides.The cyclodextrins used comply with the formula: ##STR1## in which n is equal to 6, 7 or 8 and the R.sup.1, which can be the same or different, represent OH or SR.sup.2 with R.sup.2 representing a group derived from a monosaccharide or an oligosaccharide.The Ginkgolide is preferably Ginkgolide B.

Abstract: The invention relates to substituted derivatives of per(3,6-anhydro)cyclodextrins, their preparation process and their use for the separation of ions.These derivatives comply with one of the formulas: ##STR1## in which the R.sup.1, which can be the same or different, represent H, a halogen, OH, OR.sub.2, OM, SH, SR.sup.2, OCOR.sup.2, NH.sub.2, NR.sup.2 R.sup.3, CONR.sup.2 R.sup.3, CONH.sub.2, CN, COOR.sup.2, COOH, OSO.sub.2 R.sup.2, N.sub.3 or R.sup.2, and n=5, 6 or 7, provided that all the R.sup.1 do not represent OH.

Abstract: The invention relates to the use of mono-3,6-anhydrocyclodextrins for solubilizing a hydrophobic compound and for controlling the purity of an enantiomer.The mono-3,6-anhydrocyclodextrin complies with the following formula: ##STR1## in which n is equal to 5, 6 or 7. Preferably n is equal to 6. The hydrophobic compound can be a steroid such as prednisolone.

Abstract: The invention relates to novel cyclodextrin derivatives according to formula: ##STR1## in which R.sup.1 represents OH or NH(CH.sub.2).sub.p OH, n is equal to 5, 6 or 7 and p is an integer from 2 to 6, it being possible for the p to be different when one or more of the R.sup.1 represent NH(CH.sub.2).sub.p OH.These derivatives can be used for solubilizing hydrophobic chemical compounds such as active principles in an aqueous medium by the formation of inclusion complexes therewith.