Patents by Inventor Bruno Philippe Angelo Cammue
Bruno Philippe Angelo Cammue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20080092252Abstract: Disclosed herein are methods and means of achieving enhanced expression of a target nucleotide sequence in a transgenic organism, which methods comprise the steps of: (i) providing an organism in which post-transcriptional gene silencing (PTGS) is suppressed, (ii) associating said target nucleotide sequence with one or more heterologous Matrix Attachment Region (MARs), and (iii) causing or permitting expression from the target nucleotide sequence in the organism. Unexpectedly, the MARs do not merely relieve gene silencing, but can actually lead to expression levels higher than can be achieved in wild-type organisms and higher than expression levels in organisms in which PTGS is suppressed but where the MARs are not employed.Type: ApplicationFiled: November 30, 2004Publication date: April 17, 2008Applicant: PLANT BIOSCIENCE LIMITEDInventors: Bruno Philippe Angelo Cammue, Miguel Francesco Coleta De Bolle, Katleen Butaye
-
Patent number: 6521590Abstract: Biocidal proteins capable of isolation from seeds have been characterized. The proteins have an amino acid sequence containing the common cysteine/glycine domain of Chitin-binding Plant Proteins but show substantially better activity against pathogenic fungi, a higher ratio of basic amino acids to acidic amino acids, and/or antifungal activity which results in increased hyphal branching. Antimicrobial proteins isolated from Amaranthus, Capsicum, Briza and related species are provided. The proteins show a wide range of antifungal activity and are active against Gram-positive bacteria. DNA encoding the proteins may be isolated and incorporated into vectors. Plants may be transformed with this DNA. The proteins find agricultural or pharmaceutical application as antifungal or antibacterial agents. Transgenic plants expressing the protein will show increased disease resistance.Type: GrantFiled: April 29, 1999Date of Patent: February 18, 2003Assignee: Zeneca, Ltd.Inventors: Willem Frans Broekaert, Bruno Philippe Angelo Cammue, Rupert William Osborn, Sarah Bronwen Rees, Jozef Vanderleyden
-
Patent number: 5942663Abstract: Biocidal proteins isolated from Mirabilis have been characterized. The proteins show a wide range of antifungal activity and are active against gram-positive bacteria. DNA encoding the proteins has been isolated and incorporated into vectors. Plants transformed with this DNA have been produced. The proteins find commercial application as antifungal or antibacterial agents; transformed plants will show increased disease-resistance.Type: GrantFiled: August 20, 1997Date of Patent: August 24, 1999Assignee: Zeneca LimitedInventors: Miguel De Bolle, Willem Frans Broekaert, Bruno Philippe Angelo Cammue, Sarah Bronwen Rees, Jozef Vanderleyden
-
Patent number: 5919918Abstract: Antimicrobial proteins capable of isolation from seeds of Heuchera or Aesculus show a wide range of antifungal activity and some activity against Gram-positive bacteria. DNA encoding the proteins may be isolated and incorporated into vectors. Plants transformed with this DNA may be produced. The proteins find commercial application as antifungal or antibacterial agents; transformed plants will show increased disease-resistance.Type: GrantFiled: October 23, 1997Date of Patent: July 6, 1999Assignee: Zeneca LimitedInventors: Willem Frans Broekaert, Bruno Philippe Angelo Cammue, Rupert William Osborn, Sarah Bronwen Rees
-
Patent number: 5773694Abstract: Antimicrobial proteins capable of isolation from seeds of Allium show a wide range of antifungal activity and some activity against Gram-positive bacteria. DNA encoding the proteins may be isolated and incorporated into vectors. Plants transformed with this DNA may be produced. The proteins find commercial application as antifungal or antibacterial agents; transformed plants will show increased disease resistance.Type: GrantFiled: January 25, 1996Date of Patent: June 30, 1998Assignee: Zeneca LimitedInventors: Willem Frans Broekaert, Bruno Philippe Angelo Cammue, Sarah Bronwen Rees
-
Patent number: 5750504Abstract: Antimicrobial proteins capable of isolation from seeds of Heuchera or Aesculus show a wide range of antifungal activity and some activity against Gram-positive bacteria. DNA encoding the proteins may be isolated and incorporated into vectors. Plants transformed with this DNA may be produced. The proteins find commercial application as antifungal or antibacterial agents; transformed plants will show increased disease-resistance.Type: GrantFiled: June 12, 1996Date of Patent: May 12, 1998Assignee: Zeneca AgrochemicalsInventors: Willem Frans Broekaert, Bruno Philippe Angelo Cammue, Rupert William Osborn, Sarah Bronwen Rees
-
Patent number: 5691199Abstract: Biocidal proteins capable of isolation from seeds have been characterized. The proteins have an amino acid sequence containing the common cysteine/glycine domain of Chitin-binding Plant Proteins but show substantially better activity against pathogenic fungi, a higher ratio of basic amino acids to acidic amino acids, and/or antifungal activity which results in increased hyphal branching. Antimicrobial proteins isolated from Amaranthus, Capsicum, Briza and related species are provided. The proteins show a wide range of antifungal activity and are active against Gram-positive bacteria. DNA encoding the proteins may be isolated and incorporated into vectors. Plants may be transformed with this DNA. The proteins find agricultural or pharmaceutical application as antifungal or antibacterial agents. Transgenic plants expressing the protein will show increased disease resistance.Type: GrantFiled: May 26, 1995Date of Patent: November 25, 1997Assignee: Zeneca LimitedInventors: Willem Frans Broekaert, Bruno Philippe Angelo Cammue, Sarah Bronwen Rees, Jozef Vanderleyden
-
Patent number: 5689048Abstract: Biocidal proteins isolated from Mirabilis have been characterised. The proteins show a wide range of antifungal activity and are active against gram-positive bacteria. DNA encoding the proteins has been isolated and incorporated into vectors. Plants transformed with this DNA have been produced. The proteins find commercial application as antifungal or antibacterial agents; transformed plants will show increased disease-resistance.Type: GrantFiled: June 2, 1995Date of Patent: November 18, 1997Assignee: Zeneca LimitedInventors: Miguel De Bolle, Willem Frans Broekaert, Bruno Philippe Angelo Cammue, Sarah Bronwen Rees, Jozef Vanderleyden