Abstract: The invention provides antibodies that specifically bind to Plasminogen Activator inhibitor type-1 (PAI-1), The invention also provides pharmaceutical compositions, as well as nucleic acids encoding anti-PAI-1 antibodies, recombinant expression vectors and host cells for making such antibodies, or fragments thereof. Methods of using antibodies to modulate PAI-1 activity or detect PAI-1, either in vitro or in vivo, are also provided. The disclosure further provides methods of making antibodies that specifically bind to PAI-1 in the active conformational state.

Abstract: The invention provides antibodies that specifically bind to Plasminogen Activator inhibitor type-1 (PAI-1). The invention also provides pharmaceutical compositions, as well as nucleic acids encoding anti-PAI-1 antibodies, recombinant expression vectors and host cells for making such antibodies, or fragments thereof. Methods of using antibodies to modulate PAT-1 activity or detect PAI-1, either in vitro or in vivo, are also provided. The disclosure further provides methods of making antibodies that specifically bind to PAT-1 in the active conformational state.

Abstract: The invention provides antibodies that specifically bind to Plasminogen Activator Inhibitor type-1 (PAI-1). The invention also provides pharmaceutical compositions, as well as nucleic acids encoding anti-PAI-1 antibodies, recombinant expression vectors and host cells for making such antibodies, or fragments thereof. Methods of using antibodies to modulate PAI-1 activity or detect PAI-1, either in vitro or in vivo, are also provided. The disclosure further provides methods of making antibodies that specifically bind to PAI-1 in the active conformational state.

Abstract: The invention provides antibodies that specifically bind to Plasminogen Activator Inhibitor type-1 (PAI-1), The invention also provides pharmaceutical compositions, as well as nucleic acids encoding anti-PAI-1 antibodies, recombinant expression vectors and host cells for making such antibodies, or fragments thereof. Methods of using antibodies to modulate PAI-1 activity or detect PAI-1, either in vitro or in vivo, are also provided. The disclosure further provides methods of making antibodies that specifically bind to PAI-1 in the active conformational state.

Abstract: {4-[5-(3-chloro-phenoxy)-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-acetic acid or a pharmaceutically acceptable salt thereof for use in the prevention or treatment of AKI (acute kidney injury). Medicament and pharmaceutical composition thereof.

Abstract: {4-[5-(3-chloro-phenoxy)-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-acetic acid or a pharmaceutically acceptable salt thereof for use in the prevention or treatment of AKI (acute kidney injury). Medicament and pharmaceutical composition thereof.

Abstract: An overhead tower assembly comprising an overhead tower, a threading device attached to the tower and defining an opening, a cable positioned through the opening, and a cable catcher attached to the cable. The catcher includes a body secured to the cable and sized to fit through the opening, and an arm attached to the body and movable relative to the body between a collapsed position, having a cross-section smaller than the opening, and an expanded position, having a cross-section larger than the opening. The catcher and can be used to perform a method including attaching the catcher to the cable, inserting an end of the cable through the threading device, pulling the cable through the threading device, contacting the arm with the threading device, moving the arm from the expanded position toward the collapsed position, continuing to pull the cable until the catcher has passed through the threading device, and moving the arm back to the expanded position.

Abstract: An overhead tower assembly comprising an overhead tower, a threading device attached to the tower and defining an opening, a cable positioned through the opening, and a cable catcher attached to the cable. The catcher includes a body secured to the cable and sized to fit through the opening, and an arm attached to the body and movable relative to the body between a collapsed position, having a cross-section smaller than the opening, and an expanded position, having a cross-section larger than the opening. The catcher and can be used to perform a method including attaching the catcher to the cable, inserting an end of the cable through the threading device, pulling the cable through the threading device, contacting the arm with the threading device, moving the arm from the expanded position toward the collapsed position, continuing to pull the cable until the catcher has passed through the threading device, and moving the arm back to the expanded position.