Abstract: A laser device for treating a target region of biological tissue comprises: a sheath; at least two optical fibers in the sheath, each configured to guide a laser beam to the target region, distal ends of at least two of the optical fibers configured so that each emits a laser beam in a different direction; a system of laser sources configured to generate at least two laser beams, the two laser beams having different or identical wavelengths with adjustable power; and a laser-beam control unit configured to control the system of laser sources so as to select the wavelength, the power, the duration of the deposition of laser energy, and the moment of emission of each of the laser beams in the direction of the target region so as to dynamically generate and adjust a 3D thermal distribution having a geometric shape matching a geometric shape of the target region.

Abstract: An assembly for heat-treatment of biological tissue comprises: a thermal energy generator; an energy applicator; an MRI image acquisition device for generating anatomical images and phase images; a planning unit comprising an MRI image processing means for defining a target region, a region to be preserved, and a neutral region in the tissue, and for assigning a heat treatment setpoint and an acceptable temperature measurement uncertainty to the three regions; a unit for monitoring evolution of the status of the heat treatment and for receiving data from the planning unit and from the MRI image acquisition device during a heat treatment, the monitoring unit comprising a means for generating temperature images from the phase images, a means for calculating a reliability indicator from the temperature variation indicated on the temperature image, and a means for calculating an indicator of the status of the heat treatment in the three regions.

Abstract: An ultrasound cardiac stimulation system includes: a system for measuring the heart electrical activity; a system for generating a beam of focussed ultrasound signals focussed on a targeted zone, the signals being calibrated to generate electrical stimulation in a zone of the heart, the beam generation being synchronised with a first selected time of the electrocardiogram, the generation of the beam corresponding to a pulse with a duration of less than 80 ms; a system for locating the targeted zone coupled with a system for positioning the system for generating the focussed beam to control the beam of focussed ultrasound signals in the targeted zone, the location system being synchronised with the system for generating the beam of focussed signals; a single monitoring system following in real time a temperature and tissue deformation in the targeted zone, the monitoring system taking measurements in synchronisation with the rhythm of the electrocardiogram.

Abstract: A system for ablating or monitoring a zone of the heart, includes a system to measure the heart electrical activity; a phased array for generating a beam of focussed ultrasound signals on a targeted zone of the heart; an imaging system determining an image of a transcostal wall projected in an image plane of the phased array by taking into consideration a position and direction of the phased array and making it possible to deactivate elements of the phased array in accordance with the position of the elements with regard to the position of the projected image of the transcostal wall; a positioning system to control the position of a focussed zone of a beam of focussed ultrasound signals on the targeted zone, a monitoring system to measure a temperature and tissue deformation in the targeted zone; and a device for measuring a level of cavitation in the targeted zone.

Abstract: An ultrasound cardiac stimulation system includes: a system for measuring the heart electrical activity; a system for generating a beam of focussed ultrasound signals focussed on a targeted zone, the signals being calibrated to generate electrical stimulation in a zone of the heart, the beam generation being synchronised with a first selected time of the electrocardiogram, the generation of the beam corresponding to a pulse with a duration of less than 80 ms; a system for locating the targeted zone coupled with a system for positioning the system for generating the focussed beam to control the beam of focussed ultrasound signals in the targeted zone, the location system being synchronised with the system for generating the beam of focussed signals; a single monitoring system following in real time a temperature and tissue deformation in the targeted zone, the monitoring system taking measurements in synchronisation with the rhythm of the electrocardiogram.

Abstract: A system for ablating or monitoring a zone of the heart, includes a system to measure the heart electrical activity; a phased array for generating a beam of focussed ultrasound signals on a targeted zone of the heart; an imaging system determining an image of a transcostal wall projected in an image plane of the phased array by taking into consideration a position and direction of the phased array and making it possible to deactivate elements of the phased array in accordance with the position of the elements with regard to the position of the projected image of the transcostal wall; a positioning system to control the position of a focussed zone of a beam of focussed ultrasound signals on the targeted zone, a monitoring system to measure a temperature and tissue deformation in the targeted zone; and a device for measuring a level of cavitation in the targeted zone.

Abstract: The invention concerns an assembly for heat treatment of a region of a biological tissue (410) comprising energy-generating means (100) to supply energy to the region; means (200) for measuring and recording spatial temperature distribution in said region; a control unit (300) comprising means for point-to-point digital processing of the temperature distribution in the region. The invention is characterised in that the energy-generating means comprise means(110) for spatial and temporal distribution of the power available to them on said region, the control unit (300) comprising means (330, 350), based on the temperature distribution, for controlling the amount and distribution of energy supplied by the generating means (100).

Abstract: The invention concerns an assembly for heat treatment of a region of a biological tissue (410) comprising energy-generating means (100) to supply energy to the region; means (200) for measuring and recording spatial temperature distribution in said region; a control unit (300) comprising means for point-to-point digital processing of the temperature distribution in the region. The invention is characterised in that the energy-generating means comprise means(110) for spatial and temporal distribution of the power available to them on said region, the control unit (300) comprising means (330, 350), based on the temperature distribution, for controlling the amount and distribution of energy supplied by the generating means (100).

Abstract: The inventive device for treating a biological tissue volume by a localised hyperthermy comprises a plurality of active percutaneous electrodes (1-N), at least one return electrode (120) and a high-frequency (100) electric generator for applying an alternating voltage between said active electrodes and return electrode.

Abstract: The invention concerns an assembly for heat treatment of a region of a biological tissue (410) comprising energy-generating means (100) to supply energy to the region; means (200) for measuring and recording spatial temperature distribution in said region; a control unit (300) comprising means for point-to-point digital processing of the temperature distribution in the region. The invention is characterised in that the energy-generating means comprise means(110) for spatial and temporal distribution of the power available to them on said region, the control unit (300) comprising means (330, 350), based on the temperature distribution, for controlling the amount and distribution of energy supplied by the generating means (100).