Patents by Inventor Bruno Reihl
Bruno Reihl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9119579Abstract: A microdialysis probe including a probe body, a supply line and a discharge line for a perfusion solution and a dialysis membrane, wherein a probe needle for introduction into a tissue is provided by a generally elongate frame. The frame has at least one recess at least partially open for receiving at least a portion of the supply and discharge lines. The invention encompasses a method for making such a probe, wherein the method includes arranging a dialysis membrane on a shaping device, shaping the dialysis membrane in a selected shape, applying an adhesive agent to the dialysis membrane to keep the membrane in the selected shape, and separating the dialysis membrane and the shaping devices after the adhesive agent has been applied.Type: GrantFiled: February 22, 2012Date of Patent: September 1, 2015Inventors: Matthew Carr, Bruno Reihl, Hanspeter Heiniger, Stefan Jost
-
Publication number: 20120216386Abstract: A microdialysis probe including a probe body, a supply line and a discharge line for a perfusion solution and a dialysis membrane, wherein a probe needle for introduction into a tissue is provided by a generally elongate frame. The frame has at least one recess at least partially open for receiving at least a portion of the supply and discharge lines. The invention encompasses a method for making such a probe, wherein the method includes arranging a dialysis membrane on a shaping device, shaping the dialysis membrane in a selected shape, applying an adhesive agent to the dialysis membrane to keep the membrane in the selected shape, and separating the dialysis membrane and the shaping devices after the adhesive agent has been applied.Type: ApplicationFiled: February 22, 2012Publication date: August 30, 2012Applicant: ROCHE DIAGNOSTICS INTERNATIONAL AGInventors: Matthew Carr, Bruno Reihl, Hanspeter Heiniger, Stefan Jost
-
Patent number: 8142389Abstract: A microdialysis probe including a probe body, a supply line and a discharge line for a perfusion solution and a dialysis membrane, wherein a probe needle for introduction into a tissue is provided by a generally elongate frame. The frame has at least one recess at least partially open for receiving at least a portion of the supply and discharge lines. The invention encompasses a method for making such a probe, wherein the method includes arranging a dialysis membrane on a shaping device, shaping the dialysis membrane in a selected shape, applying an adhesive agent to the dialysis membrane to keep the membrane in the selected shape, and separating the dialysis membrane and the shaping devices after the adhesive agent has been applied.Type: GrantFiled: April 1, 2005Date of Patent: March 27, 2012Assignee: Roche Diagnostics International AGInventors: Matthew Carr, Bruno Reihl, Hanspeter Heiniger, Stefan Jost
-
Patent number: 7828763Abstract: A microdialysis probe with a probe body, a probe needle for introduction into a tissue, an inlet line and an outlet line for a perfusion solution and a dialysis membrane, wherein at least one hollow channel forms the outlet line and extends at least partly spirally about the probe needle on an external surface of the probe needle. The inlet for the perfusion solution may also be in the form of spiral about the external surface of the probe needle.Type: GrantFiled: November 15, 2007Date of Patent: November 9, 2010Assignee: Roche Diagnostics International AGInventors: Gavin Wright, Bruno Reihl, Hanspeter Heiniger, Ulrich Haueter
-
Patent number: 7824382Abstract: A needle for medical uses, for example for inserting a dialysis membrane into human or animal tissue, wherein the needle has an end portion made of solid material and provided with at least two areas which intersect a longitudinal axis of the needle and each other whereby at least one line or point of intersection is formed between the at least two areas, the line or point of intersection in a needle region adjacent to the end portion.Type: GrantFiled: November 23, 2005Date of Patent: November 2, 2010Assignee: Roche Diagnostics International AGInventors: Bruno Reihl, Hanspeter Heiniger
-
Publication number: 20080228131Abstract: A microdialysis probe with a probe body, a probe needle for introduction into a tissue, an inlet line and an outlet line for a perfusion solution and a dialysis membrane, wherein at least one hollow channel forms the outlet line and extends at least partly spirally about the probe needle on an external surface of the probe needle. The inlet for the perfusion solution may also be in the form of spiral about the external surface of the probe needle.Type: ApplicationFiled: November 15, 2007Publication date: September 18, 2008Inventors: Gavin Wright, Bruno Reihl, Hanspeter Heiniger, Ulrich Haueter
-
Patent number: 7107086Abstract: A device for the in-vivo measuring of a constituent of a body fluid, the device including a light emitter which emits light in a wavelength range to which the constituent is sensitive and which is implantable in living tissue, and a light detector which, when the device is in a measuring position, receives the light emitted by the emitter and outputs a signal depending on the amount of light received, from which signal the constituent may be measured, wherein the light detector is situated outside the tissue when the device is in the measuring position.Type: GrantFiled: September 5, 2002Date of Patent: September 12, 2006Assignee: Disetronic Licensing AGInventors: Bruno Reihl, Ulrich Haueter
-
Publication number: 20060135917Abstract: A needle for medical uses, for example for inserting a dialysis membrane into human or animal tissue, wherein the needle has an end portion made of solid material and provided with at least two areas which intersect a longitudinal axis of the needle and each other whereby at least one line or point of intersection is formed between the at least two areas, the line or point of intersection in a needle region adjacent to the end portion.Type: ApplicationFiled: November 23, 2005Publication date: June 22, 2006Inventors: Bruno Reihl, Hanspeter Heiniger
-
Publication number: 20050277820Abstract: A microdialysis probe with a probe body, a probe needle for introduction into a tissue, an inlet line and an outlet line for a perfusion solution and a dialyis membrane, wherein at least one hollow channel forms the outlet line and extends at least partly spirally about the probe needle on an external surface of the probe needle. The inlet for the perfusion solution may also be in the form of spiral about the external surface of the probe needle.Type: ApplicationFiled: April 1, 2005Publication date: December 15, 2005Inventors: Gavin Wright, Bruno Reihl, Hanspeter Heiniger, Ulrich Haueter
-
Publication number: 20050251087Abstract: A microdialysis probe including a probe body, a supply line and a discharge line for a perfusion solution and a dialysis membrane, wherein a probe needle for introduction into a tissue is provided by a generally elongate frame. The frame has at least one recess at least partially open for receiving at least a portion of the supply and discharge lines. The invention encompasses a method for making such a probe, wherein the method includes arranging a dialysis membrane on a shaping device, shaping the dialysis membrane in a selected shape, applying an adhesive agent to the dialysis membrane to keep the membrane in the selected shape, and separating the dialysis membrane and the shaping devices after the adhesive agent has been applied.Type: ApplicationFiled: April 1, 2005Publication date: November 10, 2005Inventors: Matthew Carr, Bruno Reihl, Hanspeter Heiniger, Stefan Jost
-
Patent number: 6637470Abstract: A device for transferring a fluid product from one container to another including a hollow needle suitable for piercing a membrane and having a first, front opening, the needle being connectable to one of the containers via a first, rear hollow needle opening so that the fluid product can be conveyed into or out of the container through the hollow needle and hollow needle openings, the needle having a second, rear opening which forms a fluid connection between the another container and a pressure compensation device or the environment while the fluid is being transferred.Type: GrantFiled: February 25, 2002Date of Patent: October 28, 2003Assignee: Disetronic Licensing AGInventors: Bruno Reihl, Michel Hirsiger, Bruno Boos, Hanspeter Stoller, Edgar Hommann, Paolo Pollak, Peter Latscha, Sandra Soniec, Andreas Eberhart
-
Publication number: 20030050542Abstract: A device for the in-vivo measuring of a constituent of a body fluid, the device including a light emitter which emits light in a wavelength range to which the constituent is sensitive and which is implantable in living tissue, and a light detector which, when the device is in a measuring position, receives the light emitted by the emitter and outputs a signal depending on the amount of light received, from which signal the constituent may be measured, wherein the light detector is situated outside the tissue when the device is in the measuring position.Type: ApplicationFiled: September 5, 2002Publication date: March 13, 2003Inventors: Bruno Reihl, Ulrich Haueter
-
Publication number: 20020189705Abstract: A device for transferring a fluid product from one container to another including a hollow needle suitable for piercing a membrane and having a first, front opening, the needle being connectable to one of the containers via a first, rear hollow needle opening so that the fluid product can be conveyed into or out of the container through the hollow needle and hollow needle openings, the needle having a second, rear opening which forms a fluid connection between the another container and a pressure compensation device or the environment while the fluid is being transferred.Type: ApplicationFiled: February 25, 2002Publication date: December 19, 2002Inventors: Bruno Reihl, Michel Hirsiger, Bruno Boos, Hanspeter Stoller, Edgar Hommann, Paolo Pollak, Peter Latscha, Sandra Soniec, Andreas Eberhart
-
Patent number: 5737086Abstract: A spectrometer is described with a new intensity detector for electromagnetic radiation. The detector comprises means for detecting the deflection of a cantilever which has a bimetallic/bimorph structure. The deflection is proportional to the absorbed amount of radiation.Type: GrantFiled: April 24, 1996Date of Patent: April 7, 1998Assignee: International Business Machines CorporationInventors: Christoph Gerber, James Kazimierz Gimzewski, Bruno Reihl, Rato Rudolf Schlittler
-
Patent number: 5547774Abstract: A recording and reproducing method for binary coded information and a suitable recording medium are described, which use endohedrally doped cagelike molecules 30, especially fullerenes and derivatives thereof, as storage elements. By applying a probing tip 36 to the molecule for the read/write process an enhanced storage density is achieved.Type: GrantFiled: September 1, 1993Date of Patent: August 20, 1996Assignee: International Business Machines CorporationInventors: James Gimzewski, Michele Parrinello, Bruno Reihl
-
Patent number: 4698502Abstract: An Auger electron microscope is equipped with a field-emission tip maintained at an essentially constant distance above the surface of the specimen. The tip may consist of a tungsten (100) whisker having a radius of .about.50 nm at the apex, the working distance being on the order of 1 mm. Auger electrons emitted from the surface of the specimen are collected by an electron energy analyzer for conventional processing. Mutual scanning displacement between the tip and specimen is obtained through use of an xyz-drive module, which is also responsible for adjusting the working distance of the tip. The entire microscope setup is mounted on vibration damping means and may be inserted into a vacuum system by means of an appropriate flange, if desired.Type: GrantFiled: January 24, 1986Date of Patent: October 6, 1987Assignee: International Business Machines CorporationInventors: Johannes G. Bednorz, James K. Gimzewski, Bruno Reihl