Patents by Inventor Bruno Reihl

Bruno Reihl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9119579
    Abstract: A microdialysis probe including a probe body, a supply line and a discharge line for a perfusion solution and a dialysis membrane, wherein a probe needle for introduction into a tissue is provided by a generally elongate frame. The frame has at least one recess at least partially open for receiving at least a portion of the supply and discharge lines. The invention encompasses a method for making such a probe, wherein the method includes arranging a dialysis membrane on a shaping device, shaping the dialysis membrane in a selected shape, applying an adhesive agent to the dialysis membrane to keep the membrane in the selected shape, and separating the dialysis membrane and the shaping devices after the adhesive agent has been applied.
    Type: Grant
    Filed: February 22, 2012
    Date of Patent: September 1, 2015
    Inventors: Matthew Carr, Bruno Reihl, Hanspeter Heiniger, Stefan Jost
  • Publication number: 20120216386
    Abstract: A microdialysis probe including a probe body, a supply line and a discharge line for a perfusion solution and a dialysis membrane, wherein a probe needle for introduction into a tissue is provided by a generally elongate frame. The frame has at least one recess at least partially open for receiving at least a portion of the supply and discharge lines. The invention encompasses a method for making such a probe, wherein the method includes arranging a dialysis membrane on a shaping device, shaping the dialysis membrane in a selected shape, applying an adhesive agent to the dialysis membrane to keep the membrane in the selected shape, and separating the dialysis membrane and the shaping devices after the adhesive agent has been applied.
    Type: Application
    Filed: February 22, 2012
    Publication date: August 30, 2012
    Applicant: ROCHE DIAGNOSTICS INTERNATIONAL AG
    Inventors: Matthew Carr, Bruno Reihl, Hanspeter Heiniger, Stefan Jost
  • Patent number: 8142389
    Abstract: A microdialysis probe including a probe body, a supply line and a discharge line for a perfusion solution and a dialysis membrane, wherein a probe needle for introduction into a tissue is provided by a generally elongate frame. The frame has at least one recess at least partially open for receiving at least a portion of the supply and discharge lines. The invention encompasses a method for making such a probe, wherein the method includes arranging a dialysis membrane on a shaping device, shaping the dialysis membrane in a selected shape, applying an adhesive agent to the dialysis membrane to keep the membrane in the selected shape, and separating the dialysis membrane and the shaping devices after the adhesive agent has been applied.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: March 27, 2012
    Assignee: Roche Diagnostics International AG
    Inventors: Matthew Carr, Bruno Reihl, Hanspeter Heiniger, Stefan Jost
  • Patent number: 7828763
    Abstract: A microdialysis probe with a probe body, a probe needle for introduction into a tissue, an inlet line and an outlet line for a perfusion solution and a dialysis membrane, wherein at least one hollow channel forms the outlet line and extends at least partly spirally about the probe needle on an external surface of the probe needle. The inlet for the perfusion solution may also be in the form of spiral about the external surface of the probe needle.
    Type: Grant
    Filed: November 15, 2007
    Date of Patent: November 9, 2010
    Assignee: Roche Diagnostics International AG
    Inventors: Gavin Wright, Bruno Reihl, Hanspeter Heiniger, Ulrich Haueter
  • Patent number: 7824382
    Abstract: A needle for medical uses, for example for inserting a dialysis membrane into human or animal tissue, wherein the needle has an end portion made of solid material and provided with at least two areas which intersect a longitudinal axis of the needle and each other whereby at least one line or point of intersection is formed between the at least two areas, the line or point of intersection in a needle region adjacent to the end portion.
    Type: Grant
    Filed: November 23, 2005
    Date of Patent: November 2, 2010
    Assignee: Roche Diagnostics International AG
    Inventors: Bruno Reihl, Hanspeter Heiniger
  • Publication number: 20080228131
    Abstract: A microdialysis probe with a probe body, a probe needle for introduction into a tissue, an inlet line and an outlet line for a perfusion solution and a dialysis membrane, wherein at least one hollow channel forms the outlet line and extends at least partly spirally about the probe needle on an external surface of the probe needle. The inlet for the perfusion solution may also be in the form of spiral about the external surface of the probe needle.
    Type: Application
    Filed: November 15, 2007
    Publication date: September 18, 2008
    Inventors: Gavin Wright, Bruno Reihl, Hanspeter Heiniger, Ulrich Haueter
  • Patent number: 7107086
    Abstract: A device for the in-vivo measuring of a constituent of a body fluid, the device including a light emitter which emits light in a wavelength range to which the constituent is sensitive and which is implantable in living tissue, and a light detector which, when the device is in a measuring position, receives the light emitted by the emitter and outputs a signal depending on the amount of light received, from which signal the constituent may be measured, wherein the light detector is situated outside the tissue when the device is in the measuring position.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: September 12, 2006
    Assignee: Disetronic Licensing AG
    Inventors: Bruno Reihl, Ulrich Haueter
  • Publication number: 20060135917
    Abstract: A needle for medical uses, for example for inserting a dialysis membrane into human or animal tissue, wherein the needle has an end portion made of solid material and provided with at least two areas which intersect a longitudinal axis of the needle and each other whereby at least one line or point of intersection is formed between the at least two areas, the line or point of intersection in a needle region adjacent to the end portion.
    Type: Application
    Filed: November 23, 2005
    Publication date: June 22, 2006
    Inventors: Bruno Reihl, Hanspeter Heiniger
  • Publication number: 20050277820
    Abstract: A microdialysis probe with a probe body, a probe needle for introduction into a tissue, an inlet line and an outlet line for a perfusion solution and a dialyis membrane, wherein at least one hollow channel forms the outlet line and extends at least partly spirally about the probe needle on an external surface of the probe needle. The inlet for the perfusion solution may also be in the form of spiral about the external surface of the probe needle.
    Type: Application
    Filed: April 1, 2005
    Publication date: December 15, 2005
    Inventors: Gavin Wright, Bruno Reihl, Hanspeter Heiniger, Ulrich Haueter
  • Publication number: 20050251087
    Abstract: A microdialysis probe including a probe body, a supply line and a discharge line for a perfusion solution and a dialysis membrane, wherein a probe needle for introduction into a tissue is provided by a generally elongate frame. The frame has at least one recess at least partially open for receiving at least a portion of the supply and discharge lines. The invention encompasses a method for making such a probe, wherein the method includes arranging a dialysis membrane on a shaping device, shaping the dialysis membrane in a selected shape, applying an adhesive agent to the dialysis membrane to keep the membrane in the selected shape, and separating the dialysis membrane and the shaping devices after the adhesive agent has been applied.
    Type: Application
    Filed: April 1, 2005
    Publication date: November 10, 2005
    Inventors: Matthew Carr, Bruno Reihl, Hanspeter Heiniger, Stefan Jost
  • Patent number: 6637470
    Abstract: A device for transferring a fluid product from one container to another including a hollow needle suitable for piercing a membrane and having a first, front opening, the needle being connectable to one of the containers via a first, rear hollow needle opening so that the fluid product can be conveyed into or out of the container through the hollow needle and hollow needle openings, the needle having a second, rear opening which forms a fluid connection between the another container and a pressure compensation device or the environment while the fluid is being transferred.
    Type: Grant
    Filed: February 25, 2002
    Date of Patent: October 28, 2003
    Assignee: Disetronic Licensing AG
    Inventors: Bruno Reihl, Michel Hirsiger, Bruno Boos, Hanspeter Stoller, Edgar Hommann, Paolo Pollak, Peter Latscha, Sandra Soniec, Andreas Eberhart
  • Publication number: 20030050542
    Abstract: A device for the in-vivo measuring of a constituent of a body fluid, the device including a light emitter which emits light in a wavelength range to which the constituent is sensitive and which is implantable in living tissue, and a light detector which, when the device is in a measuring position, receives the light emitted by the emitter and outputs a signal depending on the amount of light received, from which signal the constituent may be measured, wherein the light detector is situated outside the tissue when the device is in the measuring position.
    Type: Application
    Filed: September 5, 2002
    Publication date: March 13, 2003
    Inventors: Bruno Reihl, Ulrich Haueter
  • Publication number: 20020189705
    Abstract: A device for transferring a fluid product from one container to another including a hollow needle suitable for piercing a membrane and having a first, front opening, the needle being connectable to one of the containers via a first, rear hollow needle opening so that the fluid product can be conveyed into or out of the container through the hollow needle and hollow needle openings, the needle having a second, rear opening which forms a fluid connection between the another container and a pressure compensation device or the environment while the fluid is being transferred.
    Type: Application
    Filed: February 25, 2002
    Publication date: December 19, 2002
    Inventors: Bruno Reihl, Michel Hirsiger, Bruno Boos, Hanspeter Stoller, Edgar Hommann, Paolo Pollak, Peter Latscha, Sandra Soniec, Andreas Eberhart
  • Patent number: 5737086
    Abstract: A spectrometer is described with a new intensity detector for electromagnetic radiation. The detector comprises means for detecting the deflection of a cantilever which has a bimetallic/bimorph structure. The deflection is proportional to the absorbed amount of radiation.
    Type: Grant
    Filed: April 24, 1996
    Date of Patent: April 7, 1998
    Assignee: International Business Machines Corporation
    Inventors: Christoph Gerber, James Kazimierz Gimzewski, Bruno Reihl, Rato Rudolf Schlittler
  • Patent number: 5547774
    Abstract: A recording and reproducing method for binary coded information and a suitable recording medium are described, which use endohedrally doped cagelike molecules 30, especially fullerenes and derivatives thereof, as storage elements. By applying a probing tip 36 to the molecule for the read/write process an enhanced storage density is achieved.
    Type: Grant
    Filed: September 1, 1993
    Date of Patent: August 20, 1996
    Assignee: International Business Machines Corporation
    Inventors: James Gimzewski, Michele Parrinello, Bruno Reihl
  • Patent number: 4698502
    Abstract: An Auger electron microscope is equipped with a field-emission tip maintained at an essentially constant distance above the surface of the specimen. The tip may consist of a tungsten (100) whisker having a radius of .about.50 nm at the apex, the working distance being on the order of 1 mm. Auger electrons emitted from the surface of the specimen are collected by an electron energy analyzer for conventional processing. Mutual scanning displacement between the tip and specimen is obtained through use of an xyz-drive module, which is also responsible for adjusting the working distance of the tip. The entire microscope setup is mounted on vibration damping means and may be inserted into a vacuum system by means of an appropriate flange, if desired.
    Type: Grant
    Filed: January 24, 1986
    Date of Patent: October 6, 1987
    Assignee: International Business Machines Corporation
    Inventors: Johannes G. Bednorz, James K. Gimzewski, Bruno Reihl