Patents by Inventor Bruno Romanò

Bruno Romanò has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Resolution of racemic beta-aminosulfone compounds
    Patent number: 11149003
    Abstract: It is described an industrially viable and advantageous process for the preparation of (S)-beta-aminosulfone (1) starting from the corresponding racemic compound, said (S)-beta-aminosulfone being a useful intermediate for the preparation of N-(2-((1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl)acetamide, also known as Apremilast, the latter being suitable for use in methods of treating, preventing and/or managing psoriasis or psoriatic arthritis.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: October 19, 2021
    Assignee: Quimica Sintetica, S.A.
    Inventors: Giuseppe Barreca, Giovanni Marras, Bruno Romanò
  • RESOLUTION OF RACEMIC BETA-AMINOSULFONE COMPOUNDS
    Publication number: 20200199072
    Abstract: It is described an industrially viable and advantageous process for the preparation of (S)-beta-aminosulfone (1) starting from the corresponding racemic compound, said (S)-beta-aminosulfone being a useful intermediate for the preparation of N-(2-((1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl)acetamide, also known as Apremilast, the latter being suitable for use in methods of treating, preventing and/or managing psoriasis or psoriatic arthritis.
    Type: Application
    Filed: March 28, 2018
    Publication date: June 25, 2020
    Applicant: Quimica Sintetica, S.A.
    Inventors: Giuseppe Barreca, Giovanni Marras, Bruno Romanò
  • Process for the preparation of 6-halo-pregnanes
    Patent number: 4188322
    Abstract: The invention relates to a new process for the preparation of 6.alpha.-halo-3-keto-.DELTA..sup.1,4 -pregnadiene-derivatives in two-steps-synthesis affording directly 6.alpha.-halo-derivatives by reacting 3-keto-9.beta.,11.beta.-oxido-.DELTA..sup.1,4 -pregnadiene-derivatives with a suitable acylating or etherifying agent to give the corresponding new 3-enol-derivatives which are finally halogenated by using a suitable halogenating agent.
    Type: Grant
    Filed: April 28, 1978
    Date of Patent: February 12, 1980
    Assignee: Blasinachim S.p.A.
    Inventors: Pier P. Castelli, Bruno Romano
  • (N-Substituted-pyridyl)-alkyl sulfonic acid betaines as electroplating additives
    Patent number: 4120859
    Abstract: Novel pyridyl alkyl sulfonic acid betaines useful as additives to nickel electroplating baths.
    Type: Grant
    Filed: July 15, 1977
    Date of Patent: October 17, 1978
    Assignee: Cilag-Chemie A.G.
    Inventors: Kurt Pluss, Bruno Romano De Martin
  • Electroplating additives
    Patent number: 4067785
    Abstract: Novel pyridyl alkyl sulfonic acid betaines useful as additives to nickel electroplating baths.
    Type: Grant
    Filed: January 27, 1977
    Date of Patent: January 10, 1978
    Assignee: Cilag-Chemie A.G.
    Inventors: Kurt Pluss, Bruno Romano De Martin