Patents by Inventor Bruno Simoneau

Bruno Simoneau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND USE THEREOF IN THE EXPANSION OF STEM CELLS AND/OR PROGENITOR CELLS
    Publication number: 20230338429
    Abstract: The invention relates to compounds as described herein and pharmaceutical compositions containing them. Also, the invention relates to methods for expanding stem cells and/or progenitor cells and methods for treating a hematopoietic disorder/malignancy, an autoimmune disease and/or an inherited immunodeficient disease.
    Type: Application
    Filed: May 19, 2023
    Publication date: October 26, 2023
    Applicant: Universite De Montreal
    Inventors: Bruno SIMONEAU, Yves CHANTIGNY, Jonathan YEH, Guy SAUVAGEAU, Anne MARINIER
  • Compounds and use thereof in the expansion of stem cells and/or progenitor cells
    Patent number: 11696928
    Abstract: The invention relates to compounds as described herein and pharmaceutical compositions containing them. Also, the invention relates to methods for expanding stem cells and/or progenitor cells and methods for treating a hematopoietic disorder/malignancy, an autoimmune disease and/or an inherited immunodeficient disease.
    Type: Grant
    Filed: November 1, 2018
    Date of Patent: July 11, 2023
    Assignee: UNIVERSITE DE MONTREAL
    Inventors: Bruno Simoneau, Yves Chantigny, Jonathan Yeh, Guy Sauvageau, Anne Marinier
  • COMPOUNDS AND USE THEREOF IN THE EXPANSION OF STEM CELLS AND/OR PROGENITOR CELLS
    Publication number: 20200323923
    Abstract: The invention relates to compounds as described herein and pharmaceutical compositions containing them. Also, the invention relates to methods for expanding stem cells and/or progenitor cells and methods for treating a hematopoietic disorder/malignancy, an autoimmune disease and/or an inherited immunodeficient disease.
    Type: Application
    Filed: November 1, 2018
    Publication date: October 15, 2020
    Applicant: UNIVERSITE DE MONTREAL
    Inventors: Bruno SIMONEAU, Yves CHANTIGNY, Jonathan YEH, Guy SAUVAGEAU, Anne MARINIER
  • Inhibitors of HIV replication
    Patent number: 9399645
    Abstract: Compounds of formula (I) and pharmaceutical compositions thereof: wherein A1 A2 and A3 are each independently selected from the group consisting of N and CR3, wherein R1 is an optionally substituted heterocyclyl or an optionally substituted —(C1-6)alkyl-heterocyclyl, R2 is an optionally substituted aryl or an optionally subsisted heteroaryl, R4 is an optionally substituted aryl, an optionally substituted heterocyclyl or an optionally substituted heteroaryl, useful as an inhibitor of HIV replication.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: July 26, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Claudio Sturino, Pierre Beaulieu, Patrick Deroy, Martin Duplessis, Clint James, Jean-Eric Lacoste, Joannie Minville, Louis Morency, Sébastien Morin, Bruno Simoneau, Martin Tremblay
  • INHIBITORS OF HIV REPLICATION
    Publication number: 20150011531
    Abstract: Compounds of formula (I) and pharmaceutical compositions thereof: wherein A1 A2 and A3 are each independently selected from the group consisting of N and CR3, wherein R1 is an optionally substituted heterocyclyl or an optionally substituted —(C1-6)alkyl-heterocyclyl, R2 is an optionally substituted aryl or an optionally subsisted heteroaryl, R4 is an optionally substituted aryl, an optionally substituted heterocyclyl or an optionally substituted heteroaryl, useful as an inhibitor of HIV replication.
    Type: Application
    Filed: December 19, 2012
    Publication date: January 8, 2015
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Claudio Sturino, Pierre Beaulieu, Patrick Deroy, Martin Duplessis, Clint James, Jean-Eric Lacoste, Joannie Minville, Louis Morency, Sébastien Morin, Bruno Simoneau, Martin Tremblay
  • INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20140296228
    Abstract: Compounds of formula I: wherein R4, R6 and R7 are defined herein, are useful as inhibitors of HIV replication.
    Type: Application
    Filed: February 28, 2014
    Publication date: October 2, 2014
    Applicant: Gilead Sciences, Inc.
    Inventors: Youla S. Tsantrizos, Murray D. Bailey, Francois Bilodeau, Rene Coulombe, Teddy Halmos, Stephen Kawai, Serge R. Landry, Steven LaPlante, Sebastien Morin, Marc-Andre Poupart, Bruno Simoneau, Lee Fader, Rebekah J. Carson, Mathieu Parisien
  • Inhibitors of human immunodeficiency virus replication
    Patent number: 8841331
    Abstract: Compounds of formula I: wherein a, R1, R2, R3, R4, R5 and R6 are defined herein, are useful as inhibitors of HIV replication.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: September 23, 2014
    Assignee: Gilead Sciences, Inc.
    Inventors: Christiane Yoakim, Murray D. Bailey, Francois Bilodeau, Rebekah Carson, Lee Fader, Stephen Kawai, Sebastien Morin, Carl Thibeault, Bruno Simoneau, Simon Surprenant, Youla S. Tsantrizos, Steven R. Laplante
  • Inhibitors of human immunodeficiency virus replication
    Patent number: 8710230
    Abstract: Compounds of formula I: wherein R4, R6 and R7 are defined herein, are useful as inhibitors of HIV replication.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: April 29, 2014
    Assignee: Gilead Sciences, Inc.
    Inventors: Youla S. Tsantrizos, Murray D. Bailey, Francois Bilodeau, Rene Coulombe, Teddy Halmos, Stephen Kawai, Serge R. Landry, Steven LaPlante, Sebastien Morin, Marc-Andre Poupart, Bruno Simoneau, Lee Fader, Rebekah J. Carson, Mathieu Parisien
  • Derivatives of 1-Phenyl-1,5-Dihydro-Benzo[B] [1,4]Diazepine-2,4-Dione as Inhibitors of HIV Replication
    Publication number: 20130150350
    Abstract: Compounds of formula (I) wherein m, R1, R2, R3, X and Y are defined herein, are useful as inhibitors of HIV replication.
    Type: Application
    Filed: February 9, 2011
    Publication date: June 13, 2013
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Bruno Simoneau, Patrick Deroy, Lee Fader, Anne-Marie Faucher, Alexander Gagnon, Chantal Grand-Maitre, Stephen Kawai, Serge Landry, Jean-Francois Mercier, Jean Rancourt
  • Inhibitors of human immunodeficiency virus replication
    Patent number: 8461180
    Abstract: Compounds of formula (I): wherein c, X, Y, R2, R4 and R5 are defined herein, are useful as inhibitors of HIV replication.
    Type: Grant
    Filed: November 13, 2008
    Date of Patent: June 11, 2013
    Assignee: Gilead Sciences, Inc.
    Inventors: Youla S. Tsantrizos, Murray D. Bailey, Punit-Kumar Bhardwaj, Christian Brochu, Paul J. Edwards, Lee Fader, Araz Jakalian, Stephen Kawai, Mathieu Parisien, Marc-Andre Poupart, Bruno Simoneau
  • Inhibitors of human immunodeficiency virus replication
    Patent number: 8377960
    Abstract: Compounds of formula I: wherein c, R2, R3, R4, R5, R6, R7 and R8 are defined herein, are useful as inhibitors of HIV replication.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: February 19, 2013
    Assignee: Gilead Sciences, Inc.
    Inventors: Youla S. Tsantrizos, Murray D. Bailey, François Bilodeau, Rebekah J. Carson, Lee Fader, Teddy Halmos, Stephen Kawai, Serge R. Landry, Steven Laplantea, Bruno Simoneau
  • Inhibitors of human immunodeficiency virus replication
    Patent number: 8354429
    Abstract: Compounds of formula I: wherein R4, R6 and R7 are defined herein, are useful as inhibitors of HIV replication.
    Type: Grant
    Filed: September 11, 2008
    Date of Patent: January 15, 2013
    Assignee: Gilead Sciences, Inc.
    Inventors: Youla S. Tsantrizos, Murray D. Bailey, Francois Bilodeau, Rebekah J. Carson, Rene Coulombe, Lee Fader, Teddy Halmos, Stephen Kawai, Serge Landry, Steven LaPlante, Sebastien Morin, Mathieu Parisien, Marc-Andre Poupart, Bruno Simoneau
  • Inhibitors of human immunodeficiency virus replication
    Patent number: 8338441
    Abstract: Compounds of formula I: wherein a, R1, R2, R3, R4, R5 and R6 are defined herein, are useful as inhibitors of HIV replication.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: December 25, 2012
    Assignee: Gilead Sciences, Inc.
    Inventors: Christiane Yoakim, Murray Bailey, Francois Bilodeau, Rebekah Carson, Lee Fader, Stephen Kawai, Sebastien Morin, Carl Thibeault, Bruno Simoneau, Simon Surprenant, Youla Tsantrizos, Steven Laplante
  • Non-nucleoside reverse transcriptase inhibitors
    Patent number: 8198458
    Abstract: Compounds of formula (I): wherein Ar, X, R1, R2, R3 and R4 are as defined herein. The compounds are useful as reverse transcriptase inhibitors against wild type and single or double mutant strains of HIV.
    Type: Grant
    Filed: February 3, 2009
    Date of Patent: June 12, 2012
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Patrick DeRoy, Anne-Marie Faucher, Alexandre Gagnon, Serge R. Landry, Sebastien Morin, Jeffrey O'Meara, Bruno Simoneau, Bounkham Thavonekham, Christiane Yoakim
  • Inhibitors of human immunodeficiency virus replication
    Patent number: 7956068
    Abstract: The present invention relates to compounds of formula (I) wherein c, X, Y, R2, R3, R4 and R6 are as defined herein, compositions and uses thereof for treating human immunodeficiency virus (HIV) infection. In particular, the present invention provides novel inhibitors of HIV integrase, pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HIV infection.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: June 7, 2011
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Rebekah J. Carson, Lee Fader, Stephen Kawai, Serge R. Landry, Youla S. Tsantrizos, Christian Brochu, Sebastien Morin, Mathieu Parisien, Bruno Simoneau
  • INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20110118249
    Abstract: Compounds of formula (I): wherein c, X, Y, R2, R4 and R5 are defined herein, are useful as inhibitors of HIV replication.
    Type: Application
    Filed: November 13, 2008
    Publication date: May 19, 2011
    Applicant: BOEHRINGER INGLEHEIM INTERNATIONAL GMBH
    Inventors: Youla S. Tsantrizos, Murray D. Bailey, Punit-Kumar Bhardwaj, Christian Brochu, Paul J. Edwards, Lee Fader, Araz Jakalian, Stephen Kawai, Mathieu Parisien, Marc-Andre Poupart, Bruno Simoneau
  • INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20110028464
    Abstract: Compounds of formula I: wherein c, R2, R3, R4, R5, R6, R7 and R8 are defined herein, are useful as inhibitors of HIV replication.
    Type: Application
    Filed: November 3, 2008
    Publication date: February 3, 2011
    Applicant: BOEHRINGER INGLEHEIM INTERNATIONAL GMBH
    Inventors: Youla S. Tsantrizos, Murray D. Bailey, François Bilodeau, Rebekah J. Carson, Lee Fader, Teddy Halmos, Stephen Kawai, Serge R. Landry, Steven Laplante, Bruno Simoneau
  • INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20100311735
    Abstract: Compounds of formula I: wherein R4, R6 and R7 are defined herein, are useful as inhibitors of HIV replication.
    Type: Application
    Filed: September 11, 2008
    Publication date: December 9, 2010
    Applicant: BOEHRINGER INGLEHEIM INTERNATIONAL GMBH
    Inventors: Youla S. Tsantrizos, Murray D. Bailey, Francois Bilodeau, Rene Coulombe, Teddy Halmos, Stephen Kawai, Serge R. Landry, Steven LaPlante, Sebastien Morin, Marc-Andre Poupart, Bruno Simoneau, Lee Fader, Rebekah J. Carson, Mathieu Parisien
  • INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20100305115
    Abstract: The present invention relates to compounds of formula (I) wherein c, X, Y, R2, R3, R4 and R6 are as defined herein, compositions and uses thereof for treating human immunodeficiency virus (HIV) infection.
    Type: Application
    Filed: November 3, 2008
    Publication date: December 2, 2010
    Applicant: BOEHRINGER INGLEHEIM INTERNATIONAL GMBH
    Inventors: Rebekah J. Carson, Lee Fader, Stephen Kawai, Serge R. Landry, Youla S. Tsantrizos, Christian Brochu, Sebastien Morin, Mathieu Parisien, Bruno Simoneau
  • INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20100292227
    Abstract: Compounds of formula I: wherein a, R1, R2, R3, R4, R5 and R6 are defined herein, are useful as inhibitors of HIV replication.
    Type: Application
    Filed: May 11, 2010
    Publication date: November 18, 2010
    Applicant: BOEHRINGER INGLEHEIM INTERNATIONAL GMBH
    Inventors: CHRISTIANE YOAKIM, MURRAY BAILEY, FRANCOIS BILODEAU, REBEKAH CARSON, LEE FADER, STEPHEN KAWAI, SEBASTIEN MORIN, CARL THIBEAULT, BRUNO SIMONEAU, SIMON SURPRENANT, YOULA TSANTRIZOS, STEVEN LAPLANTE