Abstract: A replica plating device for use with an open-ended container which holds a plurality of cells on a culture medium therein comprises a substantially planar pressing member. A side wall extends upwardly from the pressing member and surrounds same. A skirt is connected to the side wall and extends downwardly from its connection point in the direction toward said pressing member along the exterior surface of said side wall in spaced relation thereto. As a result, the side wall and skirt form a hook for maintaining the device in position on the container to allow limited, controlled movement of the device for replica plating of cells within the container. A method of using a device substantially as described above for obtaining print-replicas of cells or the like is also within the purview of the present invention.

Abstract: A roller bottle for cell growth culturing comprises an outer housing defining a hollow chamber therein. At least one annular member is inside the chamber spaced a short radial distance inwardly from the housing. The space between the annular member and the housing is in fluid communication with the chamber. The surfaces of the annular members and the interior surface of the housing are adapted to grow cells thereon.