Abstract: The present disclosure is drawn to loop-mediated isothermal amplification (LAMP) reaction assemblies including a substantially hygroscopic agent free LAMP reagent mixture in combination with a solid-phase reaction medium. The present disclosure also includes systems for a chromatic LAMP analysis including a substantially non-reactive solid phase reaction medium, and a non-interfering reagent mixture. The present disclosure also includes solid phase LAMP reaction mediums comprising a substrate, an adhesive layer disposed on the substrate, a reaction layer disposed on the adhesive layer, and a spreading layer disposed on the reaction layer. The present disclosure also includes methods of testing for a presence of a target nucleotide sequence including providing a biological sample, and dispensing the sample into a test environment having a solid phase reaction medium in combination with a LAMP reagent mixture and a pH sensitive dye.

Abstract: A technology is described for a system for identifying a colorimetric test result from a pathogen test performed on a solid phase substrate. The system can comprise a sensor configured to detect a spectrum of color wavelengths. The system can comprise one or more processors. The one or more processors can be configured to: receive color wavelength data; determine a wavelength threshold for providing a pathogen positive test result; identify whether the color wavelength data meets or exceeds the wavelength threshold for providing a pathogen positive test result; and generate a result indicator indicating either a pathogen positive or pathogen negative test result.

Abstract: The present disclosure is drawn to loop-mediated isothermal amplification (LAMP) reaction assemblies including a substantially hygroscopic agent free LAMP reagent mixture in combination with a solid-phase reaction medium. The present disclosure also includes systems for a chromatic LAMP analysis including a substantially non-reactive solid phase reaction medium, and a non-interfering reagent mixture. The present disclosure also includes solid phase LAMP reaction mediums comprising a substrate, an adhesive layer disposed on the substrate, a reaction layer disposed on the adhesive layer, and a spreading layer disposed on the reaction layer. The present disclosure also includes methods of testing for a presence of a target nucleotide sequence including providing a biological sample, and dispensing the sample into a test environment having a solid phase reaction medium in combination with a LAMP reagent mixture and a pH sensitive dye.

Abstract: A liquid biological sample test cartridge is disclosed. The cartridge can include a tray. The cartridge can also include a chemical reaction pad supported by the tray. The cartridge can further include a chemical reaction pad cover disposed over the chemical reaction pad and coupled to the tray. The chemical reaction pad cover can have a sample opening to facilitate depositing a liquid biological sample at a predetermined location on the chemical reaction pad. In addition, the cartridge can include an outer cover operable to at least partially form an enclosure about the chemical reaction pad.

Abstract: A heating device for testing a biological sample is disclosed. The heating device can include a heat source operable to generate heat. In addition, the heating device can include a controller in communication with the heat source and operable to control heat generation by the heat source to heat a biological sample at less than or equal to about 2 degrees C./s. Furthermore, a heating device for testing a biological sample is disclosed that can include a heat source operable to generate heat to heat a biological sample. The biological sample can be at least partially contained within a removable enclosure distinct from the heating device. Additionally, the heating device can include an enclosure interface associated with the heat source. The enclosure interface can be configured to interface with the enclosure such that heat is transferred from the heat source to the enclosure by conduction.

Abstract: A method of and apparatus for breaking stone rock or other frangible material and separating fines from the resultant mixture, having a cyclonic breaking zone in a lower part of a housing in which a rotor operates to break up larger pieces, the action causing fines to rise in the housing for discharging from an upper region of the housing. Alternative positions for exits for the fines are in the wall or roof of the housing or in a shelf which extends outwardly beyond the wall confining the breaking zone.

Abstract: Mineral impact breaking apparatus uses a divided flow with the first part of the flow being accelerated preferably through a rotor and discharged towards an impact breaking surface. The second part of the mineral flow is introduced into the path of the accelerated first part of the flow so that there is impacting between the first and second flows of minerals and with the second flow acting as anvil blocks against which the first flow particles will be impacted and broken. Where the horizontal accelerating rotor is used to accelerate the first part of the mineral flow the kinetic energy of the rapidly rotating air above the rotor is used to direct an air flow back to the infeed of the rotor and minimize dust discharge.

Abstract: A rotary mineral breaker has wear tip over which the mineral pieces are passed when discharged from the rotor. A supplementary wear tip is provided as a back up for the main wear tip so that failure of the main wear tip will not result in undue damage occurring to the rotor. Also the main wear tip is provided as two interchangeable pieces to improve the useful life of the wear tip.

Abstract: A mineral breaker with a horizontally mounted driven accelerating rotor having a mineral inlet on the under surface thereof and with material to be processed being drawn into the rotor in a flow of air. The processed material is discharged also in a flow of air through a tube or tubes from the top of the rotor housing. Mineral pieces not sufficiently reduced in size may be recirculated through the rotor and additional material added for further processing. The size of processed particles is controlled by the airflow passing through the rotor.