Abstract: Systems and methods for the treatment of bladder conditions using direct electrical pacing are provided. The systems and methods generally apply high-frequency pacing stimuli directly to the bladder wall, from one or more of the inner and outer bladder surfaces.

Abstract: Aspects of the present disclosure are directed toward apparatuses, systems, and methods for delivering therapy to an adrenal gland of a patient. The apparatuses, systems, and methods may include a lead body that attaches to a portion of the adrenal gland of the patient; and a plurality of electrodes arranged along the lead body. In addition, one or more of the plurality of electrodes may deliver stimulation energy to modulate catecholamine release from chromaffin cells within the adrenal gland.

Abstract: Devices, systems, and methods for regulating glucose levels, including treating diabetes, in accordance with the present disclosure may include a catheter having an expandable or inflatable portion, one or more electrodes disposed on the expandable or inflatable portion of the catheter, wherein the electrodes are configured to deliver energy to a patient's gastrointestinal tract, and a drug delivery mechanism for delivering a drug therapy subsequent to energy delivery by the electrodes. A method for regulating glucose levels according to the present disclosure may include inserting a catheter into a patient's gastrointestinal tract, positioning the catheter in a duodenum of the patient's gastrointestinal tract, expanding or inflating a portion of the catheter in the duodenum, the expandable or inflatable portion of the catheter including electrodes, applying energy to the duodenum via the electrodes to ablate tissue of the duodenum, and delivering a drug therapy to the ablated tissue of the duodenum.

Abstract: A method of forming a thermal protection system for high speed aircraft is described. The method includes mechanically working an uncured ablator material into a first surface of a felt layer such that the ablator material penetrates a distance into a thickness of the felt layer thereby forming an region that has a mixture of felt and ablator material, adding additional uncured ablator material to the worked ablator material, and curing the combined ablator material.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods for delivering therapy to an adrenal gland of a patient. The apparatuses, systems, and methods may include a plurality of stimulation elements arranged configured to deliver stimulation energy through at least one of the plurality of stimulation elements to modulate aldosterone levels within the patient.

Abstract: The present disclosure relates generally to systems and methods for detecting and monitoring the exercise pressor reflex. In some embodiments, a medical system includes a first sensor connected to a user, wherein the first sensor detects an exertion metric of the user, and a second sensor connected to the user, wherein the second sensor detects a blood pressure metric of the user. The medical system may further include a processing component in communication with the first and second sensors, wherein the processing component is capable of processing the exertion metric and the blood pressure metric to determine an elevated blood pressure metric of the user based on a comparison between a baseline blood pressure metric and the detected blood pressure metric. The processing component may further determine an exercise pressor reflex (EPR) metric based on a comparison between the elevated blood pressure metric and the exertion metric.

Abstract: The disclosure relates to a method of making molybdenum films utilizing boron and molybdenum nucleation layers. The resulting molybdenum films have low electrical resistivity, are substantially free of boron, and can be made at reduced temperatures compared to conventional chemical vapor deposition processes that do not use the boron or molybdenum nucleation layers. The molybdenum nucleation layer formed by this process can protect the substrate from the etching effect of MoCl5 or MoOCl4, facilitates nucleation of subsequent CVD Mo growth on top of the molybdenum nucleation layer, and enables Mo CVD deposition at lower temperatures. The nucleation layer can also be used to control the grain sizes of the subsequent CVD Mo growth, and therefore controls the electrical resistivity of the Mo film.

Abstract: An implantable lead includes a lead body having a proximal end portion and a distal end portion. The lead body includes an insulative member having a lumen extending longitudinally between the proximal end portion and the distal end portion. The lead body also includes a generally tubular helical liner disposed coaxially with the lumen within the insulative member. A pitch of the helical liner varies along the length of the lead. The implantable lead also includes an electrode disposed along the lead body in the distal end portion thereof, and a conductor disposed within the lumen and electrically coupled to the electrode. A terminal connector is coupled to the proximal end portion of the lead body and to the conductor.

Abstract: The present disclosure relates to a bridging asymmetric haloalkynyl dicobalt hexacarbonyl precursors, and ultra high purity versions thereof, methods of making, and methods of using these bridging asymmetric haloalkynyl dicobalt hexacarbonyl precursors in a vapor deposition process. One aspect of the disclosure relates to an ultrahigh purity bridging asymmetric haloalkynyl dicobalt hexacarbonyl precursor of the formula Co2(CO)6(R3C?CR4), where R3 and R4 are different organic moieties and R4 is more electronegative or more electron withdrawing compared to R3.

Abstract: The disclosure relates to a method of making molybdenum films utilizing boron and molybdenum nucleation layers. The resulting molybdenum films have low electrical resistivity, are substantially free of boron, and can be made at reduced temperatures compared to conventional chemical vapor deposition processes that do not use the boron or molybdenum nucleation layers. The molybdenum nucleation layer formed by this process can protect the substrate from the etching effect of MoCl5 or MoOCl4, facilitates nucleation of subsequent CVD Mo growth on top of the molybdenum nucleation layer, and enables Mo CVD deposition at lower temperatures. The nucleation layer can also be used to control the grain sizes of the subsequent CVD Mo growth, and therefore controls the electrical resistivity of the Mo film.

Abstract: Aspects of the present disclosure are directed toward apparatuses, systems, and methods for delivering therapy to an adrenal gland of a patient. The apparatuses, systems, and methods may include a housing and a plurality of electrodes arranged with the housing. In addition, one or more of the plurality of electrodes may deliver stimulation energy to modulate L-dopa release.

Abstract: The present disclosure relates to the field of neuromodulation. Specifically, the present disclosure relates to systems and methods for reversibly blocking an electrical signal from travelling along a target nerve.

Abstract: Aspects of the present disclosure are directed towards apparatuses, systems, and methods that include at least one implantable medical device. The implantable medical device may include a leadless body portion configured to engage an adrenal gland of a patient and at least one electrode, arranged within the leadless body portion, configured to deliver stimulation energy to modulate catecholamine release from chromaffin cells within the adrenal gland.

Abstract: Aspects of the present disclosure are directed toward apparatuses, systems, and methods for delivering therapy to an adrenal gland of a patient. The apparatuses, systems, and methods may include a lead body that attaches to a portion of the adrenal gland of the patient; and a plurality of electrodes arranged along the lead body. In addition, one or more of the plurality of electrodes may deliver stimulation energy to modulate catecholamine release from chromaffin cells within the adrenal gland.

Abstract: The present disclosure relates to the field of denervation. Specifically, the present disclosure relates to systems and methods for preventing an electrical signal from travelling along a target nerve. In particular, the present disclosure relates to systems and methods for relieving a pulmonary symptom by denervating the internal branch of the superior laryngeal nerve.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems and methods that include a lead for at least partially surrounding a target stimulation region. In certain instances, the lead may include a first portion, a second portion that is configured to connect with the first portion to at least partially surround the target stimulation region, and at least one electrode arranged with one of the first portion and the second portion.

Abstract: A temporary implantable medical device lead includes a connector, a helically coiled conductor and a first mechanical element. The connector is configured to connect the lead to an external control module. The helically coiled conductor has a proximal end mechanically and electrically connected to the connector. The conductor includes a plurality of filars mechanically and electrically connected to the connector. The first mechanical element includes a metal tube having a plurality of longitudinally spaced grooves formed along an exterior of the tube. The plurality of longitudinally spaced grooves receives at least some of the plurality of filars. The at least some of the plurality of filars electrically connected to the first mechanical element such that the first mechanical element is configured as an electrode to deliver electrical stimulation to portions or systems of a body from the external control module.

Abstract: Systems, devices and methods for the treatment of bladder conditions using bladder visualization without the need for optical elements and for subsequent direct electrical pacing are provided. The systems, devices and methods generally apply pacing stimulus directly to the bladder wall, from one or more of the inner and outer bladder surfaces.

Abstract: Discussion of content between users of social networks is described. A request from a first user to discuss content with a recipient user in a first social network is received, wherein the recipient user has a first identifier in the first social network. A request from a second user to discuss content with the recipient user in a second social network is received, wherein the recipient user has a second identifier in the second social network. A discussion is initiated between the second user and the recipient user about the content in the second social network. The recipient user is tracked in view of the first identifier in the first social network and the second identifier in the second social network.

Abstract: Embodiments of the present invention provide an automated scheme for identifying high/low value content. Playback data from users in a social network may be periodically submitted by users of the social network. The playback data indicates segments of content, such as audio or video that the user has skipped over or tagged as low value. The playback data may also indicate segments of content that the user has repeated or tagged as high value. The playback data is then analyzed in aggregate and various clips are identified. In addition, the playback data may be compiled and organized among the users for future use. The playback data may be used to indicate segments of high/low interest to peers in the social network or to arbitrary users.