Patents by Inventor Bryan A. Irving

Bryan A. Irving has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES, ACTIVATABLE ANTIBODIES, BISPECIFIC ANTIBODIES, AND BISPECIFIC ACTIVATABLE ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20260146104
    Abstract: Provided herein are nucleic acids encoding polypeptides, antibodies, activatable antibodies (AAs), bispecific antibodies, and bispecific activatable antibodies (BAAs). Also provided herein are methods of making and methods of use of these antibodies, AAs, bispecific antibodies, and BAAs.
    Type: Application
    Filed: October 5, 2025
    Publication date: May 28, 2026
    Applicant: CytomX Therapeutics, Inc.
    Inventors: Leila Marie BOUSTANY, Sherry L. LA PORTE, Bryan A. IRVING, Jeanne Grace FLANDEZ
  • Antibodies, activatable antibodies, bispecific antibodies, and bispecific activatable antibodies and methods of use thereof
    Patent number: 12460017
    Abstract: Provided herein antibodies, activatable antibodies (AAs), bispecific antibodies, and bispecific activatable antibodies (BAAs). Also provided herein are methods of making and methods of use of these antibodies, AAs, bispecific antibodies, and BAAs.
    Type: Grant
    Filed: November 13, 2023
    Date of Patent: November 4, 2025
    Assignee: CytomX Therapeutics, Inc.
    Inventors: Leila Marie Boustany, Sherry L. La Porte, Bryan A. Irving, Jeanne Grace Flandez
  • ANTIBODIES, ACTIVATABLE ANTIBODIES, BISPECIFIC ANTIBODIES, AND BISPECIFIC ACTIVATABLE ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20240150492
    Abstract: Provided herein antibodies, activatable antibodies (AAs), bispecific antibodies, and bispecific activatable antibodies (BAAs). Also provided herein are methods of making and methods of use of these antibodies, AAs, bispecific antibodies, and BAAs.
    Type: Application
    Filed: November 13, 2023
    Publication date: May 9, 2024
    Applicant: CytomX Therapeutics, Inc.
    Inventors: Leila Marie BOUSTANY, Sherry L. LA PORTE, Bryan A. IRVING, Jeanne Grace FLANDEZ
  • Antibodies, activatable antibodies, bispecific antibodies, and bispecific activatable antibodies and methods of use thereof
    Patent number: 11859010
    Abstract: Provided herein antibodies, activatable antibodies (AAs), bispecific antibodies, and bispecific activatable antibodies (BAAs). Also provided herein are methods of making and methods of use of these antibodies, AAs, bispecific antibodies, and BAAs.
    Type: Grant
    Filed: September 7, 2022
    Date of Patent: January 2, 2024
    Assignee: CytomX Therapeutics, Inc.
    Inventors: Leila Marie Boustany, Sherry L. La Porte, Bryan A. Irving, Jeanne Grace Flandez
  • ANTIBODIES, ACTIVATABLE ANTIBODIES, BISPECIFIC ANTIBODIES, AND BISPECIFIC ACTIVATABLE ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20230050083
    Abstract: Provided herein antibodies, activatable antibodies (AAs), bispecific antibodies, and bispecific activatable antibodies (BAAs). Also provided herein are methods of making and methods of use of these antibodies, AAs, bispecific antibodies, and BAAs.
    Type: Application
    Filed: September 7, 2022
    Publication date: February 16, 2023
    Applicant: CytomX Therapeutics, Inc.
    Inventors: Leila Marie BOUSTANY, Sherry L. LA PORTE, Bryan A. IRVING, Jeanne Grace FLANDEZ
  • Antibodies, activatable antibodies, bispecific antibodies, and bispecific activatable antibodies and methods of use thereof
    Patent number: 11472889
    Abstract: Provided herein antibodies, activatable antibodies (AAs), bispecific antibodies, and bispecific activatable antibodies (BAAs). Also provided herein are methods of making and methods of use of these antibodies, AAs, bispecific antibodies, and BAAs.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: October 18, 2022
    Assignee: CYTOMX THERAPEUTICS, INC.
    Inventors: Leila Marie Boustany, Sherry L. La Porte, Bryan A. Irving, Jeanne Grace Flandez
  • ANTIBODIES, ACTIVATABLE ANTIBODIES, BISPECIFIC ANTIBODIES, AND BISPECIFIC ACTIVATABLE ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20190135943
    Abstract: Provided herein antibodies, activatable antibodies (AAs), bispecific antibodies, and bispecific activatable antibodies (BAAs). Also provided herein are methods of making and methods of use of these antibodies, AAs, bispecific antibodies, and BAAs.
    Type: Application
    Filed: October 12, 2018
    Publication date: May 9, 2019
    Inventors: Leila Marie Boustany, Sherry L. La Porte, Bryan A. Irving, Jeanne Grace Flandez
  • Chimeric chains for receptor-associated signal transduction pathways
    Publication number: 20020111474
    Abstract: Chimeric proteins and DNA encoding chimeric proteins are provided, where the chimeric proteins are characterized by an extracellular domain capable of binding to a ligand in a non-MHC restricted manner, a transmembrane domain and a cytoplasmic domain capable of activating a signaling pathway. The extracellular domain and cytoplasmic domain are not naturally found together. Binding of ligand to the extracellular domain results in transduction of a signal and activation of a signaling pathway in the cell, whereby the cell may be induced to carry out various functions relating to the signalling pathway. A wide variety of extracellular domains may be employed as receptors, where such domains may be naturally occurring or synthetic. The chimeric DNA may be used to modify lymphocytes as well as hematopoietic stem cells as precursors to a number of important cell types.
    Type: Application
    Filed: January 16, 2001
    Publication date: August 15, 2002
    Inventors: Daniel J. Capon, Arthur Weiss, Bryan A. Irving, Margo R. Roberts, Krisztina Zsebo