Patents by Inventor Bryan A. Whitson

Bryan A. Whitson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prevention and treatment of viral infection and viral infection-induced organ failure
    Patent number: 11197912
    Abstract: Compositions for and methods of preventing, reversing or treating viral infection-induced organ failure provided. The compositions are also suitable for treating and/or preventing COVID-19 and influenza. The compositions and methods employ MG53, which can be in the form of recombinant human MG53. The MG53 may also be administered as a composition that expresses and releases MG53 after in vivo administration of said composition to a subject.
    Type: Grant
    Filed: February 25, 2021
    Date of Patent: December 14, 2021
    Assignee: OHIO STATE INNOVATION FOUNDATION
    Inventors: Jianjie Ma, Jacob S. Yount, Matthew A. Sermersheim, Adam D. Kenney, Xinyu Zhou, Bryan A. Whitson, Nahush A. Mokadam, Tao Tan, Chuanxi Cai
  • Prevention and Treatment of Viral Infection and Viral Infection-Induced Organ Failure
    Publication number: 20210315968
    Abstract: Compositions for and methods of preventing, reversing or treating viral infection-induced organ failure provided. The compositions are also suitable for treating and/or preventing COVID-19 and influenza. The compositions and methods employ MG53, which can be in the form of recombinant human MG53. The MG53 may also be administered as a composition that expresses and releases MG53 after in vivo administration of said composition to a subject.
    Type: Application
    Filed: February 25, 2021
    Publication date: October 14, 2021
    Applicant: OHIO STATE INNOVATION FOUNDATION
    Inventors: JIANJIE MA, JACOB S. YOUNT, MATTHEW A. SERMERSHEIM, ADAM D. KENNEY, Xinyu ZHOU, BRYAN A. WHITSON, NAHUSH A. MOKADAM, TAO TAN, CHUANXI CAI
  • Multilayered submucosal graft constructs and method for making the same
    Patent number: 5955110
    Abstract: Multi-laminar tissue graft constructs, pseudoisotropic graft constructs and a method of preparing such constructs are described. Multi-laminar tissue graft constructs are prepared by fusing partially overlapped strips of submucosa tissue into a unitary graft construct by compressing the tissue under dehydrating conditions. Pseudoisotropic tissue graft constructs are prepared by overlapping a first strip of submucosa tissue with at least two strips of submucosa tissue orientated so that the longitudinal axis of each strip formts an angle of about 180.degree./N with the longitudinal axes of at least two other strips of submucosal tissue.
    Type: Grant
    Filed: November 12, 1996
    Date of Patent: September 21, 1999
    Assignees: Purdue Research Foundation, Inc., Methodist Hospital of Indiana, Inc.
    Inventors: Umesh H. Patel, Michael C. Hiles, Bryan A. Whitson, Boyle Cheng, Stephen F. Badylak, Klod Kokini