Patents by Inventor Bryan Allen Irving

Bryan Allen Irving has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BISPECIFIC ANTI-CD3 ANTIBODIES, BISPECIFIC ACTIVATABLE ANTI-CD3 ANTIBODIES, AND METHODS OF USING THE SAME
    Publication number: 20240084010
    Abstract: The invention relates generally to antibodies, activatable antibodies, multispecific antibodies, and multispecific activatable antibodies that specifically bind to at least CD3, as well as to methods of making and using these antibodies, activatable antibodies, multispecific antibodies, and/or multispecific activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
    Type: Application
    Filed: September 22, 2023
    Publication date: March 14, 2024
    Applicant: CytomX Therapeutics, Inc.
    Inventors: Bryan Allen IRVING, Sherry Lynn LA PORTE, Jason Gary SAGERT, Daniel Robert HOSTETTER, Olivia Jennifer RAZO, Clayton William WHITE, Jennifer Hope RICHARDSON
  • Bispecific anti-CD3 antibodies, bispecific activatable anti-CD3 antibodies, and methods of using the same
    Patent number: 11802158
    Abstract: The invention relates generally to antibodies, activatable antibodies, multispecific antibodies, and multispecific activatable antibodies that specifically bind to at least CD3, as well as to methods of making and using these antibodies, activatable antibodies, multispecific antibodies, and/or multispecific activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: October 31, 2023
    Assignee: CYTOMX THERAPEUTICS, INC.
    Inventors: Bryan Allen Irving, Sherry Lynn La Porte, Jason Gary Sagert, Daniel Robert Hostetter, Olivia Jennifer Razo, Clayton William White, Jennifer Hope Richardson
  • Multispecific antibodies, multispecific activatable antibodies and methods of using the same
    Patent number: 11161906
    Abstract: The invention relates generally to multispecific antibodies and to multispecific activatable antibodies that specifically bind to two or more different antigens or epitopes, as well as to methods of making and using these multispecific antibodies and/or multispecific activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: November 2, 2021
    Assignee: CYTOMX THERAPEUTICS, INC.
    Inventors: Henry Bernard Lowman, James William West, Sherry Lynn La Porte, Bryan Allen Irving, Daniel Robert Hostetter, Chihunt Wong
  • MULTISPECIFIC ANTIBODIES, MULTISPECIFIC ACTIVATABLE ANTIBODIES AND METHODS OF USING THE SAME
    Publication number: 20210238291
    Abstract: The invention relates generally to multispecific antibodies and to multispecific activatable antibodies that specifically bind to two or more different antigens or epitopes, as well as to methods of making and using these multispecific antibodies and/or multispecific activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
    Type: Application
    Filed: April 14, 2021
    Publication date: August 5, 2021
    Applicant: CytomX Therapeutics, Inc.
    Inventors: Henry Bernard Lowman, James Willam West, Sherry Lynn La Porte, Bryan Allen Irving, Daniel Robert Hostetter, Chihunt Wong
  • BISPECIFIC ANTI-CD3 ANTIBODIES, BISPECIFIC ACTIVATABLE ANTI-CD3 ANTIBODIES, AND METHODS OF USING THE SAME
    Publication number: 20210047406
    Abstract: The invention relates generally to antibodies, activatable antibodies, multispecific antibodies, and multispecific activatable antibodies that specifically bind to at least CD3, as well as to methods of making and using these antibodies, activatable antibodies, multispecific antibodies, and/or multispecific activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
    Type: Application
    Filed: April 24, 2020
    Publication date: February 18, 2021
    Inventors: Bryan Allen IRVING, Sherry Lynn LA PORTE, Jason Gary SAGERT, Daniel Robert HOSTETTER, Olivia Jennifer RAZO, Clayton William WHITE, Jennifer Hope RICHARDSON
  • Bispecific anti-CD3 antibodies, bispecific activatable anti-CD3 antibodies, and methods of using the same
    Patent number: 10669337
    Abstract: The invention relates generally to antibodies, activatable antibodies, multispecific antibodies, and multispecific activatable antibodies that specifically bind to at least CD3, as well as to methods of making and using these antibodies, activatable antibodies, multispecific antibodies, and/or multispecific activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: June 2, 2020
    Assignee: CytomX Therapeutics, Inc.
    Inventors: Bryan Allen Irving, Sherry Lynn La Porte, Jason Gary Sagert, Daniel Robert Hostetter, Olivia Jennifer Razo, Clayton William White, Jennifer Hope Richardson
  • ANTI-CD3 ANTIBODIES, ACTIVATABLE ANTI-CD3 ANTIBODIES, MULTISPECIFIC ANTI-CD3 ANTIBODIES, MULTISPECIFIC ACTIVATABLE ANTI-CD3 ANTIBODIES, AND METHODS OF USING THE SAME
    Publication number: 20160194399
    Abstract: The invention relates generally to antibodies, activatable antibodies, multispecific antibodies, and multispecific activatable antibodies that specifically bind to at least CD3, as well as to methods of making and using these antibodies, activatable antibodies, multispecific antibodies, and/or multispecific activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
    Type: Application
    Filed: July 24, 2015
    Publication date: July 7, 2016
    Inventors: Bryan Allen Irving, Sherry Lynn La Porte, Jason Gary Sagert, Daniel Robert Hostetter, Olivia Jennifer Razo, Clayton William White, Jennifer Hope Richardson
  • MULTISPECIFIC ANTIBODIES, MULTISPECIFIC ACTIVATABLE ANTIBODIES AND METHODS OF USING THE SAME
    Publication number: 20150079088
    Abstract: The invention relates generally to multispecific antibodies and to multispecific activatable antibodies that specifically bind to two or more different antigens or epitopes, as well as to methods of making and using these multispecific antibodies and/or multispecific activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
    Type: Application
    Filed: July 25, 2014
    Publication date: March 19, 2015
    Inventors: Henry Bernard Lowman, James William West, Sherry Lynn La Porte, Bryan Allen Irving, Daniel Robert Hostetter, Chihunt Wong
  • PDZ DOMAIN INTERACTIONS AND LIPID RAFTS
    Publication number: 20100215677
    Abstract: Methods for modulating immune cell signaling are provided. In general such methods involve modulating an interaction between a PDZ protein and a PDZ ligand protein whose interaction affects the composition and/or distribution of lipid rafts in an immune cell. Modulators that enhance or inhibit such interactions are also disclosed, as well as methods of screening for such modulators.
    Type: Application
    Filed: April 29, 2010
    Publication date: August 26, 2010
    Applicants: Arbor Vita Corporation, The General Hospital Corporation
    Inventors: Peter S. Lu, Chamorro Somoza Diaz-Sarmiento, Brian Seed, Ramnik Xavier, Bryan Allen Irving
  • PDZ domain interactions and lipid rafts
    Publication number: 20030049695
    Abstract: Methods for modulating immune cell signaling are provided. In general such methods involve modulating an interaction between a PDZ protein and a PDZ ligand protein whose interaction affects the composition and/or distribution of lipid rafts in an immune cell. Modulators that enhance or inhibit such interactions are also disclosed, as well as methods of screening for such modulators.
    Type: Application
    Filed: February 19, 2002
    Publication date: March 13, 2003
    Inventors: Peter S. Lu, Chamorro Somoza Diaz-Sarmiento, Brian Seed, Ramnik Xavier, Bryan Allen Irving