Patents by Inventor Bryan C Fuchs

Bryan C Fuchs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating liver fibrosis and pre-cirrhosis with epidermal growth factor receptor inhibitors
    Patent number: 9072741
    Abstract: This invention relates generally to a therapeutic use of epidermal growth factor receptor inhibitors to reduce fibrosis, e.g., liver fibrosis, or pre-cirrhosis in a subject.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: July 7, 2015
    Assignee: The General Hospital Corporation
    Inventors: Kenneth Tanabe, Bryan C. Fuchs
  • Epidermal growth factor (EGF) expression and/or polymorphisms thereof for predicting the risk of developing cancer
    Patent number: 8323896
    Abstract: The present invention relates to diagnostic and prognostic methods to determine the likelihood of a subject who has a inflammatory disease or liver disease of developing cancer. In particular, the present invention relates to methods for identifying subjects with increased susceptibility to developing cancer, such as hepatocellular carcinoma (HCC) where the subject has an inflammatory disease, such as, but not limited to cirrhosis, by identifying a variance or polymorphism in the human EGF gene. In particular, the methods of the present invention relate to identifying subjects with increased susceptibility to developing cancer such as HCC, where the subject has an inflammatory disease, such as but not limited to cirrhosis, and the subject is identified to have a single nucleotide polymorphism 61A>G in the 5?UTR of the EGF gene.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: December 4, 2012
    Assignee: The General Hospital Corporation
    Inventors: Kenneth K Tanabe, Bryan C Fuchs, Hiroshi Kawasaki
  • COMPOSITIONS, KITS, AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND THERAPY OF HEPATIC DISORDERS
    Publication number: 20110263441
    Abstract: The invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating hepatic disorders such as hepatocellular carcinoma and/or cirrhosis. A variety of informative biomarkers corresponding thereto, are provided, wherein alterations in expression relative to a control is correlated with the presence of a hepatic disorder, likelihood of survival from a hepatic disorder, and likelihood of recurrence of a hepatic disorder.
    Type: Application
    Filed: October 15, 2009
    Publication date: October 27, 2011
    Inventors: Todd R. Golub, Yujin Hoshida, Bryan C. Fuchs, Kenneth K. Tanabe, Josep M. Llovet Bayer, Augusto Villanueva
  • Methods of Treating Liver Fibrosis and Pre-Cirrhosis with Epidermal Growth Factor Receptor Inhibitors
    Publication number: 20110086039
    Abstract: This invention relates generally to a therapeutic use of epidermal growth factor receptor inhibitors to reduce fibrosis, e.g., liver fibrosis, or pre-cirrhosis in a subject.
    Type: Application
    Filed: October 8, 2010
    Publication date: April 14, 2011
    Applicant: GENERAL HOSPITAL CORPORATION, THE
    Inventors: Kenneth Tanabe, Bryan C. Fuchs