Patents by Inventor Bryan Clingman
Bryan Clingman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230172586Abstract: A method is disclosed for generating sinograms by sampling a plurality of transducers acoustically coupled with the surface of a volume of tissue over a period of time after a light pulse at one wavelength, and after another light pulse at a different wavelength, and for processing those sinograms, reconstructing at least two optoacoustic images from the two sinograms, processing the two optoacoustic images to generate two envelope images and generating a parametric map from information in the two envelope images. In an embodiment, motion and tracking are determined to align the envelope images. In an embodiment, at least a second parametric map is produced from information in the same two envelope images. In an embodiment an ultrasound image is also acquired, and the parametric map is coregistered with and overlayed upon the ultrasound image, and then displayed.Type: ApplicationFiled: July 21, 2022Publication date: June 8, 2023Applicant: Seno Medical Instruments, Inc.Inventors: Bryan Clingman, Jason Zalev
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Patent number: 11426147Abstract: A method is disclosed for generating sinograms by sampling a plurality of transducers acoustically coupled with the surface of a volume of tissue over a period of time after a light pulse at one wavelength, and after another light pulse at a different wavelength, and for processing those sinograms, reconstructing at least two optoacoustic images from the two sinograms, processing the two optoacoustic images to generate two envelope images and generating a parametric map from information in the two envelope images. In an embodiment, motion and tracking are determined to align the envelope images. In an embodiment, at least a second parametric map is produced from information in the same two envelope images. In an embodiment an ultrasound image is also acquired, and the parametric map is coregistered with and overlayed upon the ultrasound image, and then displayed.Type: GrantFiled: March 22, 2016Date of Patent: August 30, 2022Assignee: Seno Medical Instruments, Inc.Inventors: Bryan Clingman, Jason Zalev
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Patent number: 11375984Abstract: Systems, methods and computer program products are provided for reading and scoring ultrasound and/or optoacoustic (US/OA) images that include at least one of OA images or US images acquired in connection with an examination for a region of interest (ROI). The system displays a first image that has an interior ROI outline separating an internal zone from a boundary zone. In some aspects, feature scores are obtained in connection with at least the boundary zone and peripheral zone of the first image and the feature scores are applied to a classification model to obtain at least one of a prognostic result or predictive result indicative of a trait of the lesion. In accordance with some aspects, an order in which feature scores are entered is automatically managed to obtain for the at least one of the peripheral zone or the boundary zone before the feature score is obtained for the internal zone.Type: GrantFiled: June 18, 2020Date of Patent: July 5, 2022Assignee: Seno Medical Instruments, Inc.Inventors: Anthony Thomas Stavros, Bryan Clingman, Sandra G. Dykes
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Publication number: 20220117544Abstract: Systems, methods and computer program products are provided for analyzing at least one of ultrasound (US) images or optoacoustic (OA) images (US/OA images), comprising: a display configured to display at least a first image from at least one of OA images or US images acquired in connection with an examination for a region of interest (ROI), the first image including a lesion, the first image overlaid with an interior ROI outline separating an internal zone from a boundary zone of the ROI, the first image overlaid with an exterior ROI outline separating the boundary zone from a peripheral zone; a graphical user interface (GUI); memory configured to store program instructions; and one or more processors configured to execute the programmable instructions to: obtain feature scores in connection with at least the boundary zone and peripheral zone of the first image; apply the feature scores to a classification model to obtain predictive result indicative of a trait of the lesion, the predictive result indicatingType: ApplicationFiled: November 3, 2021Publication date: April 21, 2022Applicant: Seno Medical Instruments, Inc.Inventors: Anthony Thomas Stavros, Bryan Clingman, Sandra G. Dykes
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Patent number: 11287309Abstract: A serialized probe component for an optoacoustic device has a unique identifier associated therewith and includes, in an embodiment, an operative connection between a read-write memory and the optoacoustic device. Software adapted to generate and store logs in a read-write memory is executed on the optoacoustic device and stores logs concerning utilization of the serialized probe component on the read-write memory. A method for logging operational information concerning an optoacoustic device is further disclosed.Type: GrantFiled: July 27, 2017Date of Patent: March 29, 2022Assignee: Seno Medical Instruments, Inc.Inventors: Gregory Schmid, William Ackerman, Bryan Clingman
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Method and system for managing feature reading and scoring in ultrasound and/or optoacoustice images
Patent number: 11246527Abstract: Systems, methods and computer program products are provided for reading and scoring ultrasound and/or optoacoustic (US/OA) images that include at least one of OA images or US images acquired in connection with an examination for a region of interest (ROI). The system displays a first image that has an interior ROI outline separating an internal zone from a boundary zone. In some aspects, feature scores are obtained in connection with at least the boundary zone and peripheral zone of the first image and the feature scores are applied to a classification model to obtain at least one of a prognostic result or predictive result indicative of a trait of the lesion. In accordance with some aspects, an order in which feature scores are entered is automatically managed to obtain for the at least one of the peripheral zone or the boundary zone before the feature score is obtained for the internal zone.Type: GrantFiled: June 18, 2020Date of Patent: February 15, 2022Assignee: Seno Medical Instruments, Inc.Inventors: Anthony Thomas Stavros, Bryan Clingman, Sandra G. Dykes -
METHOD AND SYSTEM FOR MANAGING FEATURE READING AND SCORING IN ULTRASOUND AND/OR OPTOACOUSTICE IMAGES
Publication number: 20200345292Abstract: Systems, methods and computer program products are provided for reading and scoring ultrasound and/or optoacoustic (US/OA) images that include at least one of OA images or US images acquired in connection with an examination for a region of interest (ROI). The system displays a first image that has an interior ROI outline separating an internal zone from a boundary zone. In some aspects, feature scores are obtained in connection with at least the boundary zone and peripheral zone of the first image and the feature scores are applied to a classification model to obtain at least one of a prognostic result or predictive result indicative of a trait of the lesion. In accordance with some aspects, an order in which feature scores are entered is automatically managed to obtain for the at least one of the peripheral zone or the boundary zone before the feature score is obtained for the internal zone.Type: ApplicationFiled: June 18, 2020Publication date: November 5, 2020Applicant: Seno Medical Instruments, Inc.Inventors: Anthony Thomas Stavros, Bryan Clingman, Sandra G. Dykes -
METHOD AND SYSTEM FOR MANAGING FEATURE READING AND SCORING IN ULTRASOUND AND/OR OPTOACOUSTICE IMAGES
Publication number: 20200315589Abstract: Systems, methods and computer program products are provided for reading and scoring ultrasound and/or optoacoustic (US/OA) images that include at least one of OA images or US images acquired in connection with an examination for a region of interest (ROI). The system displays a first image that has an interior ROI outline separating an internal zone from a boundary zone. In some aspects, feature scores are obtained in connection with at least the boundary zone and peripheral zone of the first image and the feature scores are applied to a classification model to obtain at least one of a prognostic result or predictive result indicative of a trait of the lesion. In accordance with some aspects, an order in which feature scores are entered is automatically managed to obtain for the at least one of the peripheral zone or the boundary zone before the feature score is obtained for the internal zone.Type: ApplicationFiled: June 18, 2020Publication date: October 8, 2020Applicant: Seno Medical Instruments, Inc.Inventors: Anthony Thomas Stavros, Bryan Clingman, Sandra G. Dykes -
Patent number: 10762628Abstract: Electromagnetic energy is deposited into a volume, an acoustic return signal from energy deposited in the volume is measured, and a parametric map that estimates values of at least one parameter as spatially represented in the volume is computed. A reference level of a region of interest is determined, and upper and lower color map limits are specified, with at least one of them being determined in relation to the reference level. The parametric map is then rendered in the palette of a color map by mapping the estimated values of the parametric map onto the color map according to the color map limits. Two wavelengths of energy can be applied to the volume, and the parametric map computation can be adapted by applying an implicit or explicit model of, or theoretical basis for, distribution of electromagnetic energy fluence within the volume pertaining to the two wavelengths.Type: GrantFiled: May 15, 2019Date of Patent: September 1, 2020Assignee: Seno Medical Instruments, Inc.Inventors: Jason Zalev, Bryan Clingman
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Patent number: 10709419Abstract: A real-time imaging system that provides ultrasonic imaging and optoacoustic imaging coregistered through application of the same hand-held probe to generate and detect ultrasonic and optoacoustic signals. These signals are digitized, processed and used to reconstruct anatomical maps superimposed with maps of two functional parameters of blood hemoglobin index and blood oxygenation index. The blood hemoglobin index represents blood hemoglobin concentration changes in the areas of diagnostic interest relative to the background blood concentration. The blood oxygenation index represents blood oxygenation changes in the areas of diagnostic interest relative to the background level of blood oxygenation. These coregistered maps can be used to noninvasively differentiate malignant tumors from benign lumps and cysts.Type: GrantFiled: September 27, 2016Date of Patent: July 14, 2020Assignee: SENO MEDICAL INSTRUMENTS, INC.Inventors: Alexander A. Oraevsky, Sergey A. Ermilov, Andre Conjusteau, Peter Brecht, Vyacheslav Nadvoretskiy, Richard Su, Donald G. Herzog, Bryan Clingman, Jason Zalev
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Patent number: 10638935Abstract: An optoacoustic imaging system includes a handheld probe and first and second pulsed light sources having a common output. The first and second light sources generate pulses of light at first and second predominant wavelengths, respectively. The handheld probe includes an ultrasound transducer array having an active end located at the distal end of the handheld probe for receiving an optoacoustic return signal. A sensor measures a portion of the light transmitted along the light path. A data acquisition samples the ultrasound transducer array during a predetermined period of time after a pulse of light from the first light source and during a predetermined period of time after a pulse of light from the second light source. The sampled data is stored.Type: GrantFiled: March 20, 2019Date of Patent: May 5, 2020Assignee: Seno Medical Instruments, Inc.Inventors: Jason Zalev, Bryan Clingman, Donald G. Herzog
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Publication number: 20200113505Abstract: A system and method for performing optoacoustic classification prediction is provided. The method utilizes one or more processors in connection with receiving OA feature scores in connection with OA images collected from a patient examination for a volume of interest. The volume of interest includes a lesion. The method applies the OA feature scores to a classification model to obtain a predictive result indicative of a trait of the lesion.Type: ApplicationFiled: June 19, 2019Publication date: April 16, 2020Applicant: Seno Medical Instruments, Inc.Inventors: Bryan Clingman, Sandra G. Dykes
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Patent number: 10517481Abstract: A method for controlling an optoacoustic imaging system includes the steps of analyzing sinogram data values to identify variations, storing information concerning the variations, generating first and second sinograms, and processing the sinograms to mitigate the effect of the variations. In the analyzing step, sinogram data values are analyzed to identify one or more variations that are related to performance of one or more of the discrete components of the optoacoustic imaging system. The identified variations are then stored. A first sinogram is generated by sampling transducer elements acoustically coupled with a surface of a volume for a predetermined period of time after delivery of a pulse of light having a first wavelength, the first sinogram containing one channel for each of the transducer elements.Type: GrantFiled: July 11, 2016Date of Patent: December 31, 2019Assignee: Seno Medical Instruments, Inc.Inventors: Jason Zalev, Bryan Clingman, Gregory Schmid
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Patent number: 10433732Abstract: An optoacoustic imaging system includes a hand-held imaging probe having a light emitting portion and an array of ultrasonic transducers. The probe includes an acoustic lens having an optically reflective material that operates to avoid image artifacts associated with light interactions with the acoustic lens. The optically reflective material may be a thin, highly optically reflective metallic layer. The acoustic lens may be formed from a material such as silicone rubber filled with titanium dioxide or barium sulfate that allows it to reflect and scatter light from illumination components with substantially no absorption of such light, and yet be optically opaque. The probe may include a housing that provides hypo-echoic encapsulation of the probe. An assembly of the array of ultrasonic transducers may include a hypo-echoic material. The probe may include optical windows, each comprising one or more anti-reflection coated plates with acoustic impedance matching that of tissues to be imaged.Type: GrantFiled: January 22, 2013Date of Patent: October 8, 2019Assignee: SENO MEDICAL INSTRUMENTS, INC.Inventors: Alexander A. Oraevsky, Sergey A. Ermilov, Andre Conjusteau, Peter Brecht, Vyacheslav Nadvoretskiy, Richard Su, Donald G. Herzog, Bryan Clingman, Jason Zalev
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Publication number: 20190266725Abstract: Electromagnetic energy is deposited into a volume, an acoustic return signal from energy deposited in the volume is measured, and a parametric map that estimates values of at least one parameter as spatially represented in the volume is computed. A reference level of a region of interest is determined, and upper and lower color map limits are specified, with at least one of them being determined in relation to the reference level. The parametric map is then rendered in the palette of a color map by mapping the estimated values of the parametric map onto the color map according to the color map limits. Two wavelengths of energy can be applied to the volume, and the parametric map computation can be adapted by applying an implicit or explicit model of, or theoretical basis for, distribution of electromagnetic energy fluence within the volume pertaining to the two wavelengths.Type: ApplicationFiled: May 15, 2019Publication date: August 29, 2019Applicant: Seno Medical Instruments, Inc.Inventors: Jason Zalev, Bryan Clingman
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Publication number: 20190216332Abstract: An optoacoustic imaging system includes a handheld probe and first and second pulsed light sources having a common output. The first and second light sources generate pulses of light at first and second predominant wavelengths, respectively. The handheld probe includes an ultrasound transducer array having an active end located at the distal end of the handheld probe for receiving an optoacoustic return signal. A sensor measures a portion of the light transmitted along the light path. A data acquisition samples the ultrasound transducer array during a predetermined period of time after a pulse of light from the first light source and during a predetermined period of time after a pulse of light from the second light source. The sampled data is stored.Type: ApplicationFiled: March 20, 2019Publication date: July 18, 2019Applicant: Seno Medical Instruments, Inc.Inventors: Jason Zalev, Bryan Clingman, Donald G. Herzog
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Patent number: 10354379Abstract: Electromagnetic energy is deposited into a volume, an acoustic return signal from energy deposited in the volume is measured, and a parametric map that estimates values of at least one parameter as spatially represented in the volume is computed. A reference level of a region of interest is determined, and upper and lower color map limits are specified, with at least one of them being determined in relation to the reference level. The parametric map is then rendered in the palette of a color map by mapping the estimated values of the parametric map onto the color map according to the color map limits. Two wavelengths of energy can be applied to the volume, and the parametric map computation can be adapted by applying an implicit or explicit model of, or theoretical basis for, distribution of electromagnetic energy fluence within the volume pertaining to the two wavelengths.Type: GrantFiled: November 6, 2017Date of Patent: July 16, 2019Assignee: Seno Medical Instruments, Inc.Inventors: Jason Zalev, Bryan Clingman
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Patent number: 10349921Abstract: Systems and methods for relaying electrical signals representing acoustic response of a volume of tissue to light and ultrasound stimulation. In an embodiment, a plurality of ultrasound transducers receive acoustic energy from the volume and generate electrical energy, which is transmitted via an electrical path to a relay system. The ultrasound transducers are operated at a wide band frequency of at least 1 MHz to 5 MHz to receive acoustic energy from the volume of tissue responsive to light stimulation and at a narrower band frequency to receive acoustic energy from the volume of tissue responsive to acoustic stimulation. The relay system relays the electrical signals to an optoacoustic system or an ultrasound instrument for further processing depending on whether the electrical signals resulted from ultrasound or light stimulation. In an embodiment, optoacoustic, ultrasound, or other images are generated from the electrical signals and may be coregistered, overlayed, or displayed.Type: GrantFiled: June 30, 2017Date of Patent: July 16, 2019Assignee: Seno Medical Instruments, Inc.Inventors: Donald G. Herzog, Gregory Schmid, Bryan Clingman, Jason Zalev, William Ackerman
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Patent number: 10327647Abstract: A method is disclosed for creating and outputting a masked parametric map (e.g., hemoglobin oxygenation) that reflects parameters in a first parametric map (e.g., relative oxygenation) and second parametric map (e.g., relative hemoglobin). In an illustrative embodiment, the method comprises steps of generating a first parametric map, generating a second parametric map, and then generating a masked parametric map that reflects parameters in the first and second parametric maps. The masked map may present information not readily apparent from the first parametric map and the second parametric map, and not obtainable from the first and second parametric maps independently. The first parametric map may be based upon portions of two optoacoustic images created using differing wavelengths of light. The first parametric map is reflective of areas within the volume of tissue that have a differing response to the longer wavelength light event compared to the shorter one.Type: GrantFiled: January 25, 2019Date of Patent: June 25, 2019Assignee: Seno Medical Instruments, Inc.Inventors: Jason Zalev, Bryan Clingman
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Patent number: 10321896Abstract: Systems and methods for relaying electrical signals representing acoustic response of a volume of tissue to light and ultrasound stimulation. In an embodiment, a plurality of ultrasound transducers receive acoustic energy from the volume and generate electrical energy, which is transmitted via an electrical path to a relay system. The ultrasound transducers are operated at a wide band frequency of at least 1 MHz to 5 MHz to receive acoustic energy from the volume of tissue responsive to light stimulation and at a narrower band frequency to receive acoustic energy from the volume of tissue responsive to acoustic stimulation. The relay system relays the electrical signals to an optoacoustic system or an ultrasound instrument for further processing depending on whether the electrical signals resulted from ultrasound or light stimulation. In an embodiment, optoacoustic, ultrasound, or other images are generated from the electrical signals and may be coregistered, overlayed, or displayed.Type: GrantFiled: October 18, 2016Date of Patent: June 18, 2019Assignee: Seno Medical Instruments, Inc.Inventors: Donald G. Herzog, Gregory Schmid, Bryan Clingman, Jason Zalev, William Ackerman