Patents by Inventor Bryan D. Zerhusen
Bryan D. Zerhusen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20040030096Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: August 1, 2002Publication date: February 12, 2004Inventors: Linda Gorman, Bryan D. Zerhusen, Shlomit R. Edinger, Muralidhara Padigaru, Xiaojia (Sasha) Guo, Ramesh Kekuda, Mei Zhong, Meera Patturajan, Charles E. Miller, Weizhen Ji, Carol E. A. Pena, Catherine E. Burgess, Paul Sciore, David J. Stone, Raymond J. Taupier, Stacie J. Casman, Mark E. Rothenberg, Uriel M. Malyankar, Ferenc L. Boldog
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Publication number: 20040029216Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: January 9, 2002Publication date: February 12, 2004Inventors: Muralidhara Padigaru, Li Li, Bryan D. Zerhusen, Stacie J. Casman, Suresh G. Shenoy, Kimberly Spytek, Mei Zhong, Esha A. Gangolli, Catherine E. Burgess, Meera Patturajan, Corine A.M. Vernet, Sarah Taylor, Velizar T. Tchernev, Charles E. Miller, Xiaojia Guo, Ferenc L. Boldog, William M. Grosse, John P. Alsobrook, Valerie L. Gerlach, Shlomit R. Edinger, Mark E. Rothenberg, Karen Ellerman, John MacDougall, Uriel M. Malyankar, Isabelle Millet, John Peyman, Glennda Smithson, Erik Gunther, David Stone
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Publication number: 20040029116Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: March 1, 2002Publication date: February 12, 2004Inventors: Shlomit R. Edinger, John R. MacDougall, Isabelle Millet, Karen Ellerman, David J. Stone, Valerie Gerlach, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Daniel K. Rieger, Catherine E. Burgess, Stacie J. Casman, Kimberly A. Spytek, Ferenc L. Boldog, Li Li, Muralidhara Padigaru, Vishnu Mishra, Meera Patturajan, Suresh G. Shenoy, Luca Rastelli, Velizar T. Tchernev, Corine A.M. Vernet, Bryan D. Zerhusen, Uriel M. Malyankar, Xiaojia Guo, Charles E. Miller, Esha A. Gangolli
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Publication number: 20040029220Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: June 18, 2002Publication date: February 12, 2004Inventors: Corine A.M. Vernet, Elma R. Fernandes, Valerie Gerlach, Richard A. Shimkets, Uriel M. Malyankar, Ferenc L. Boldog, Bryan D. Zerhusen, Kimberly A. Spytek, Kumud Majumder, Velizar T. Tchernev, Muralidhara Padigaru, Meera Patturajan, Catherine E. Burgess, Esha A. Gangolli, Glennda Smithson, Luca Rastelli, John R. MacDougall, Raymond J. Taupier, William M. Grosse, Edward S. Szekeres, John P. Alsobrook, David W. Anderson, Xiaojia (Sasha) Guo, Li Li, Mei Zhong
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Publication number: 20040029790Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: July 2, 2002Publication date: February 12, 2004Inventors: Meera Patturajan, Valerie Gerlach, David W. Anderson, Raymond J. Taupier, Bryan D. Zerhusen, Xiaojia Sasha Guo, Stacie J. Casman, Tord Hjalt, Charles E. Miller, Ramesh Kekuda, Richard A. Shimkets, Uriel M. Malyankar, Mei Zhong, Muralidhara Padigaru, Li Li, Suresh G. Shenoy, Linda Gorman, Shlomit R. Edinger
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Publication number: 20040023874Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide.Type: ApplicationFiled: March 5, 2003Publication date: February 5, 2004Inventors: Catherine E. Burgess, John S. Chant, Ammitabha Chaudhuri, Shlomit R. Edinger, Esha A. Gangolli, Uriel M. Malyankar, Charles E. Miller, Chean Eng Ooi, Tatiana Ort, Meera Patturajan, Luca Rastelli, Daniel K. Rieger, Richard A. Shimkets, Bryan D. Zerhusen
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Publication number: 20040018594Abstract: Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids, polypeptides, or antibodies, or fragments thereof.Type: ApplicationFiled: May 1, 2002Publication date: January 29, 2004Inventors: John P. Alsobrook, David W. Anderson, Ferenc L. Boldog, Catherine E. Burgess, Stacie J. Casman, Andrei Chapoval, Shlomit R. Edinger, Valerie Gerlach, Linda Gorman, Erik Gunther, Xiaojia Sasha Guo, Ramesh Kekuda, Denise M. Lepley, Li Li, Xiaohong Liu, Uriel M. Malyankar, Charles E. Miller, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, Daniel K. Rieger, Suresh G. Shenoy, Richard A. Shimkets, Kimberly A. Spytek, Raymond J. Taupier, Corine A.M. Vernet, Edward Z. Voss, Bryan D. Zerhusen
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Publication number: 20040018970Abstract: Disclosed are novel polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.Type: ApplicationFiled: March 27, 2002Publication date: January 29, 2004Inventors: Richard A. Shimkets, Meera Patturajan, Corine A.M. Vernet, Stacie J. Casman, Uriel M. Malyankar, Suresh G. Shenoy, Kimberly A. Spytek, Esha A. Gangolli, Charles E. Miller, Ferenc L. Boldog, Li Li, Raymond J. Taupier, Ramesh Kekuda, Glennda Smithson, Bryan D. Zerhusen, Xiaohong Liu, Steven D. Colman, Velizar T. Tchernev, Jingsheng Si, Shlomit R. Edinger, David J. Stone, Paul Sciore, Isabelle Millet, Mark E. Rothenberg
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Publication number: 20040018196Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: January 11, 2002Publication date: January 29, 2004Inventors: Peter D. Mezes, Luca Rastelli, John L. Herrmann, John R. MacDougall, Haihong Zhong, Stacie J. Casman, Ferenc L. Boldog, Richard A. Shimkets, Linda Gorman, Andrew J. Eisen, Steven K. Spaderna, Corine A.M. Vernet, Constance Berghs, Kimberly A. Spytek, Vincent A. DiPippo, Bryan D. Zerhusen, John A. Peyman, Karen Ellerman, David J. Stone, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Daniel K. Rieger, Catherine E. Burgess, Shlomit R. Edinger
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Publication number: 20040018555Abstract: Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids, polypeptides, or antibodies, or fragments thereof.Type: ApplicationFiled: June 3, 2002Publication date: January 29, 2004Inventors: David W. Anderson, Bryan D. Zerhusen, Li Li, Mei Zhong, Stacie J. Casman, Valerie Gerlach, Richard A. Shimkets, Linda Gorman, Carol E. A. Pena, Ramesh Kekuda, Meera Patturajan, Kimberly A. Spytek, Mario W. Leite, Luca Rastelli, John R. MacDougall, Raymond J. Taupier, Xiaojia Sasha Guo, Charles E. Miller, Suresh G. Shenoy, Tord Hjalt, Edward Z. Voss, Ferenc L. Boldog, Uriel M. Malyankar, Muralidhara Padigaru, Weizhen Ji, Glennda Smithson, Shlomit R. Edinger, Isabelle Millet, Karen Ellerman
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Publication number: 20040014081Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: February 18, 2003Publication date: January 22, 2004Inventors: John P. Alsobrook, Steven K. Spaderna, Velizar T. Tchernev, Xiaohong Liu, Suresh G. Shenoy, Kimberly A. Spytek, Bryan D. Zerhusen, Meera Patturajan, Raymond J. Taupier, Luca Rastelli, William M. Grosse, Edward S. Szekeres, Denise M. Lepley, Lei Shen, Catherine E. Burgess, Richard A. Shimkets, Muralidhara Padigaru
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Publication number: 20040014058Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: October 1, 2002Publication date: January 22, 2004Inventors: John P. Alsobrook, Catherine E. Burgess, Elina Catterton, John S. Chant, Ammitabha Chaudhuri, Shlomit Edinger, Valerie Gerlach, Loic Giot, Linda Gorman, Xiaojia (Sasha) Guo, Ramesh Kekuda, Peter S. Mezes, Isabelle Millet, Chean Eng Ooi, Meera Patturajan, Daniel K. Rieger, Kimberly A. Spytek, Raymond J. Taupier, Bryan D. Zerhusen, Haihong Zhong, Mei Zhong
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Publication number: 20040014053Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: August 1, 2002Publication date: January 22, 2004Inventors: Bryan D. Zerhusen, Meera Patturajan, Ramesh Kekuda, Charles E. Miller, Daniel K. Rieger, Carol E.A. Pena, Richard A. Shimkets, Li Li, Constance Berghs, Mei Zhong, Stacie J. Casman, Edward Z. Voss, Ferenc L. Boldog, Muralidhara Padigaru, Glennda Smithson, Weizhen Ji, Linda Gorman, Corine A.M. Vernet, Mario W. Leite, Xiaojia Sasha Guo, David W. Anderson, Kimberly A. Spytek, Valerie Gerlach, Catherine E. Burgess, Nikolai V. Khramtsov, Tatiana Ort, Karen Ellerman, Luca Rastelli, Michele L. Agee, Amitabha Chaudhuri, John S. Chant, Vincent A. DiPippo, Shlomit R. Edinger, Andrew J. Eisen, Esha A. Gangolli, Loic Giot, Chean Eng Ooi, Mark E. Rothenberg, Steven K. Spaderna, Tord Hjalt, Xiaohong Liu, Raymond J. Taupier, Elina Catterton, Suresh G. Shenoy
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Publication number: 20040010118Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: August 15, 2001Publication date: January 15, 2004Inventors: Bryan D. Zerhusen, Muralidhara Padigaru, Kimberly Spytek, Steven Spaderna, Esha A. Gangolli, Luca Rastelli, Catherine E. Burgess, Kumud Majumder, Richard Shimkets, Vishnu Mishra, Corine Vernet, Edward S. Szekeres, William M. Grosse, John P. Alsobrook, Xiaohong Liu, Valerie L. Gerlach, Karen Ellerman, Glennda Smithson, John Peyman, David Stone, John MacDougall
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Publication number: 20040009907Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: February 25, 2002Publication date: January 15, 2004Inventors: John P. Alsobrook, David W. Anderson, Robert A. Ballinger, Ference L. Boldog, Catherine E. Burgess, Stacie J. Casman, Karen Ellerman, Esha A. Gangolli, Valerie Gerlach, Jennifer A. Gilbert, Linda Gorman, Xiaojia (Sasha) Guo, Vladimir Y. Gusev, Ramesh Kekuda, Li Li, Xiaohong Liu, Uriel M. Malyankar, Charles E. Miller, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, John A. Peyman, Luca Rastelli, Suresh G. Shenoy, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek, David J. Stone, Raymond J. Taupier, Velizar T. Tchernev, Corine A.M. Vernet, Bryan D. Zerhusen
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Publication number: 20040009480Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: June 3, 2002Publication date: January 15, 2004Inventors: David W. Anderson, Jason C. Baumgartner, Ferenc L. Boldog, Stacie J. Casman, Shlomit R. Edinger, Esha A. Gangolli, Valerie Gerlach, Linda Gorman, Xiaojia Sasha Guo, Tord Hjalt, Ramesh Kekuda, Li Li, John R. MacDougall, Uriel M. Malyankar, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, Luca Rastelli, Richard A. Shimkets, David J. Stone, Kimberly A. Spytek, Corine A.M. Vernet, Edward Z. Voss, Bryan D. Zerhusen
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Publication number: 20040006205Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: April 2, 2002Publication date: January 8, 2004Inventors: Li Li, Valerie Gerlach, Xiaohong Liu, Charles E. Miller, Kimberly A. Spytek, Bryan D. Zerhusen, Carol E. A. Pena, Suresh G. Shenoy, Haihong Zhong, Glennda Smithson, Stacie J. Casman, Ferenc L. Boldog, Edward Z. Voss, Corine A. Vernet, John R. MacDougall, Luca Rastelli, David W. Anderson, Mei Zhong, Peter S. Mezes, Katarzyna Furtak, Meera Patturajan, Catherine E. Burgess, Uriel M. Malyankar, Richard A. Shimkets, Raymond J. Taupier, Schlomit Edinger, Ann Mazur
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Publication number: 20040005558Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: January 18, 2002Publication date: January 8, 2004Inventors: David W. Anderson, Catherine E. Burgess, Stacie J. Casman, Steven D. Colman, Shlomit R. Edinger, Karen Ellerman, Valerie Gerlach, Erik Gunther, Ramesh Kekuda, John R. MacDougall, Fuad Mehraban, Meera Patturajan, Mark Rothenberg, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek, David J. Stone, Corine A.M. Vernet, Bryan D. Zerhusen
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Publication number: 20040005576Abstract: Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.Type: ApplicationFiled: August 30, 2002Publication date: January 8, 2004Inventors: Xiaojia (Sasha) Guo, Li Li, Meera Patturajan, Richard A. Shimkets, Stacie J. Casman, Uriel M. Malyankar, Velizar T. Tchernev, Corine A. Vernet, Kimberly A. Spytek, Suresh G. Shenoy, John P. Alsobrook, Schlomit Edinger, John A. Peyman, David J. Stone, Karen Ellerman, Esha A. Gangolli, Ferenc L. Boldog, Steven D. Colman, Andrew Eisen, Xiaohong Liu, Muralidhara Padigaru, Steven K. Spaderna, Bryan D. Zerhusen
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Publication number: 20040005557Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: January 16, 2002Publication date: January 8, 2004Inventors: Muralidhara Padigaru, John P. Alsobrook, Steven D. Colman, Kimberly A. Spytek, Ferenc L. Boldog, Corine A.M. Vernet, Li Li, Suresh G. Shenoy, Stacie J. Casman, Xiaojia (Sasha) Guo, Shlomit R. Edinger, John R. MacDougall, Uriel M. Malyankar, Meera Patturajan, Richard A. Shimkets, Carol E. A. Pena, Velizar T. Tchernev, Bryan D. Zerhusen, Isabelle Millet, Charles E. Miller, Denise M. Lepley, Glennda Smithson, Jason C. Baumgartner, John L. Herrmann, John A. Peyman, Linda Gorman, Peter D. Mezes, Ramesh Kekuda, Raymond J. Taupier, Valerie Gerlach, William M. Grosse, Xiaohong Liu, Karen Ellerman, Mark Rothenberg, David J. Stone, Catherine E. Burgess