Patents by Inventor Bryan G. Winchester

Bryan G. Winchester has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heptitols
    Patent number: 5384417
    Abstract: Novel heptitol analogues of mannofuranose and their syntheses from .delta.-lactones of heptonic acids are disclosed. The novel heptitols are (A) 2,5-dideoxy-2,5-imino-D-glycero-D-talo-heptitol and (b) 1-amino-2,5-anydro-1-deoxy-D-glycero-D-talo-heptitol. These novel heptitol compounds are useful inhibitors of glycosidases.
    Type: Grant
    Filed: January 18, 1994
    Date of Patent: January 24, 1995
    Assignee: Monsanto Company
    Inventors: George W. J. Fleet, Bryan G. Winchester
  • Heptitols
    Patent number: 5300659
    Abstract: Novel heptitol analogues of mannofuranose and their syntheses from .delta.-lactones of heptonic acids are disclosed. The novel heptitols are (A) 2,5-dideoxy-2,5-imino-D-glycero-D-talo-heptitol and (b) 1-amino-2,5-anhydro-1-deoxy-D-glycero-D-talo-heptitol. These novel heptitol compounds are useful inhibitors of glycosidases.
    Type: Grant
    Filed: June 14, 1993
    Date of Patent: April 5, 1994
    Assignee: Monsanto Company
    Inventors: George W. J. Fleet, Bryan G. Winchester
  • Pyrrolidin-3,4-diol derivatives of heptitols and preparation thereof
    Patent number: 5250703
    Abstract: Novel heptitol analogues of mannofuranose and their syntheses from .delta.-lactones of heptonic acids are disclosed. The novel heptitols are (A) 2,5-dideoxy-2,5-imino-D-glycero-D-talo-heptitol and (b) 1-amino-2,5-anhydro-1-deoxy-D-glycero-D-talo-heptitol. These novel heptitol compounds are useful inhibitors of glycosidases.
    Type: Grant
    Filed: September 29, 1992
    Date of Patent: October 5, 1993
    Assignee: Monsanto Company
    Inventors: George W. J. Fleet, Bryan G. Winchester
  • D-rhamnono-1,5-lactone
    Patent number: 5210089
    Abstract: The novel D-rhamnono-? ,5-lactone and a novel method of synthesis of said compound from the monoacetonide of L-gulono-.gamma.-lactone is disclosed. D-Rhamnono-1,5-lactone is a potent inhibitor of .alpha.-and .beta.-mannosidases but not of .alpha.-rhamnosidase.
    Type: Grant
    Filed: February 4, 1992
    Date of Patent: May 11, 1993
    Assignee: Monsanto Company
    Inventors: George W. J. Fleet, Bryan G. Winchester