Patents by Inventor Bryan Goodwin

Bryan Goodwin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Parathyroid hormone variants
    Patent number: 12291556
    Abstract: The invention relates to parathyroid hormone (PTH) variants and pharmaceutical compositions comprising same. The invention further relates to PTH compositions with improved serum half-life and peak-trough ratios, and methods of controlling serum calcium levels with the PTH variants and compositions of the invention. The invention further relates to methods of treating hypoparathyroidism and/or hypocalcemia due to hypoparathyroidism with the PTH variants and compositions of the invention.
    Type: Grant
    Filed: March 2, 2023
    Date of Patent: May 6, 2025
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Clark Pan, Angela Norton, Kevin Holmes, David Lloyd, Bryan Goodwin, Rongxin Shi, Sujit Jain, Chuan Shen
  • PARATHYROID HORMONE VARIANTS
    Publication number: 20230340057
    Abstract: The invention relates to parathyroid hormone (PTH) variants and pharmaceutical compositions comprising same. The invention further relates to PTH compositions with improved serum half-life and peak-trough ratios, and methods of controlling serum calcium levels with the PTH variants and compositions of the invention. The invention further relates to methods of treating hypoparathyroidism and/or hypocalcemia due to hypoparathyroidism with the PTH variants and compositions of the invention.
    Type: Application
    Filed: March 2, 2023
    Publication date: October 26, 2023
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Clark PAN, Angela NORTON, Kevin HOLMES, David LLOYD, Bryan GOODWIN, Rongxin SHI, Sujit JAIN, Chuan SHEN
  • Xenobiotic related induction of gene expression
    Publication number: 20060105385
    Abstract: An isolated nucleic acid molecule comprising a nucleotide sequence encoding a transcriptional enhancer of cytochrome P450 (P450) CYP3A4 production or expression, and uses of the nucleic acid molecule for screening compounds for xenobiotic induction of CYP3A4 expression in cells and animals.
    Type: Application
    Filed: January 4, 2006
    Publication date: May 18, 2006
    Applicant: The University of Sydney
    Inventors: Christopher Liddle, Bryan Goodwin
  • Compositions and methods for altering glucose production
    Publication number: 20050107441
    Abstract: Methods for identifying agents which alter glucose production by modulating expression and/or activity of the nuclear receptor short heterodimer partner or SHP are provided. Also provided are compositions containing such agents and methods of using such agents to alter glucose production in a subject.
    Type: Application
    Filed: December 18, 2002
    Publication date: May 19, 2005
    Inventors: Steven Kliewer, Bryan Goodwin, James Way
  • Transgenic animals for analysing cyp3a4 cytochrome p450 gene regulation
    Publication number: 20050076397
    Abstract: The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located between the initiation of transcription site of the gene and a position located 13,000 nucleotides upstream from the site. The invention also relates to the use of these animals for determining the effect of a compound, particularly, but not exclusively, a xenobiotic or steriod, on the regulation of expression of the CYP3A4 gene in a human.
    Type: Application
    Filed: November 1, 2001
    Publication date: April 7, 2005
    Inventors: Christopher Liddle, Bryan Goodwin, Graham Robertson