Patents by Inventor Bryan Gore

Bryan Gore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INTEIN-MEDIATED RECONSTITUTION OF VOLTAGE-GATED SODIUM CHANNEL FUNCTION
    Publication number: 20260224749
    Abstract: Artificial expression constructs for the rescue of voltage-gated sodium channel function using intein-mediated reconstitution of the SCN1A encoded protein, voltage-gated sodium channel alpha subunit 1 (Nav1.1) are described. Rescued voltage-gated sodium channel function can be used to treat disorders such as epilepsy, and more particularly, Dravet Syndrome.
    Type: Application
    Filed: February 1, 2024
    Publication date: August 6, 2026
    Applicants: Allen Institute, Seattle Children’s Hospital d/b/a Seattle Children’s Research Institute
    Inventors: Bryan Gore, Edward Sebastian Lein, Boaz P. Levi, Refugio Martinez, John K. Mich, Franck Kalume
  • ARTIFICIAL EXPRESSION CONSTRUCTS FOR MODULATING GENE EXPRESSION IN GABAERGIC NEURONS AND ASTROCYTES
    Publication number: 20240117377
    Abstract: Artificial expression constructs for modulating gene expression in GABAergic neurons and astrocytes are described. The artificial expression constructs can be used to express SLC6A1 for the treatment of SLC6A1-associated disorders, among other uses.
    Type: Application
    Filed: February 2, 2022
    Publication date: April 11, 2024
    Applicant: Allen Institute
    Inventors: Bryan Gore, Edward Sebastian Lein, Boaz P. Levi, Deja Machen, Refugio Martinez, John K. Mich, Jonathan Ting