Patents by Inventor Bryan J. Boyle

Bryan J. Boyle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND MATERIALS RELATING TO CD84-LIKE POLYPEPTIDES AND POLYNUCLEOTIDES
    Publication number: 20110268724
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: July 8, 2011
    Publication date: November 3, 2011
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian-Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Methods and compositions concerning antibodies that bind CD84-like polypeptides
    Patent number: 7981413
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: July 19, 2011
    Assignee: ARCA Biopharma Inc.
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Stem cell factor-like proteins and uses thereof
    Publication number: 20100278800
    Abstract: The invention relates to pharmaceutical compositions comprising gastrointestinal proliferative factor SCFA2, SCFA4 or SCFA4v polynucleotides and polypeptides. The invention further relates to the therapeutic use of SCFA2, SCFA4 or SCFA4v to prevent or treat conditions or disorders associated with the degeneration of the epithelial mucosa.
    Type: Application
    Filed: January 25, 2010
    Publication date: November 4, 2010
    Inventors: Bryan J. Boyle, Peter C.R. Emtage, Walter Funk, Y. Tom Tang, Jingsong Zhao
  • Stem cell factor-like proteins and uses thereof
    Patent number: 7674890
    Abstract: The invention relates to pharmaceutical compositions comprising gastrointestinal proliferative factor SCFA2, SCFA4 or SCFA4v polynucleotides and polypeptides. The invention further relates to the therapeutic use of SCFA2, SCFA4 or SCFA4v to prevent or treat conditions or disorders associated with the degeneration of the epithelial mucosa.
    Type: Grant
    Filed: April 1, 2008
    Date of Patent: March 9, 2010
    Assignee: Arca Biopharma, Inc.
    Inventors: Bryan J. Boyle, Peter C. R. Emtage, Walter Funk, Y. Tom Tang, Jingsong Zhao
  • Methods for the Diagnosis and Treatment of Preeclampsia
    Publication number: 20090280124
    Abstract: Provided by the present invention are methods for treating and diagnosing preeclampsia, as well as kits for use in diagnosing patients with a higher risk of preeclampsia.
    Type: Application
    Filed: November 10, 2008
    Publication date: November 12, 2009
    Applicant: HERA BIOMEDICAL INC.
    Inventors: Ivan Labat, Birgit Stache-Crain, Y. Tom Tang, Bryan J. Boyle, Susan Andarmani
  • Methods and Materials Relating to CD84-like Polypeptides and Polynucleotides
    Publication number: 20090042199
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: April 10, 2008
    Publication date: February 12, 2009
    Applicant: NUVELO, INC.
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian-Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Methods and Materials Relating to CD84-like Polypeptides and Polynucelotides
    Publication number: 20090023659
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: August 20, 2008
    Publication date: January 22, 2009
    Applicant: NUVELO, INC.
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Gastrointestinal proliferative factor and uses thereof
    Publication number: 20080300183
    Abstract: The invention relates to pharmaceutical compositions comprising gastrointestinal proliferative factor (GIPF) polynucleotides and polypeptides. The invention further relates to the therapeutic use of GIPF to prevent or treat conditions or disorders associated with the degeneration of the epithelial mucosa.
    Type: Application
    Filed: May 24, 2007
    Publication date: December 4, 2008
    Inventors: Bryan J. Boyle, Walter Funk, Makoto Kakitani, Takeshi Oshima, Eun Ju Park, Y. Tom Tang, Mikio Yagi, Kazuma Tomizuka
  • Methods and Materials Relating to CD84-like Polypeptides and Polynucleotides
    Publication number: 20080260747
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: April 10, 2008
    Publication date: October 23, 2008
    Applicant: NUVELO, INC.
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian-Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Stem cell factor-like proteins and uses thereof
    Patent number: 7439327
    Abstract: The invention relates to pharmaceutical compositions comprising gastrointestinal proliferative factor SCFA2, SCFA4 or SCFA4v polynucleotides and polypeptides. The invention further relates to the therapeutic use of SCFA2, SCFA4 or SCFA4v to prevent or treat conditions or disorders associated with the degeneration of the epithelial mucosa.
    Type: Grant
    Filed: January 17, 2006
    Date of Patent: October 21, 2008
    Assignee: Nuvelo, Inc.
    Inventors: Bryan J. Boyle, Peter C. R. Emtage, Walter Funk, Y. Tom Tang, Jingsong Zhao
  • Methods and materials relating to CD84-like polypeptides and polynucleotides
    Patent number: 7425610
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polyeptides.
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: September 16, 2008
    Assignee: Nuvelo, Inc.
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian-Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Stem cell factor-like proteins and uses thereof
    Publication number: 20080200388
    Abstract: The invention relates to pharmaceutical compositions comprising gastrointestinal proliferative factor SCFA2, SCFA4 or SCFA4v polynucleotides and polypeptides. The invention further relates to the therapeutic use of SCFA2, SCFA4 or SCFA4v to prevent or treat conditions or disorders associated with the degeneration of the epithelial mucosa.
    Type: Application
    Filed: April 1, 2008
    Publication date: August 21, 2008
    Applicant: NUVELO, INC.
    Inventors: Bryan J. Boyle, Peter C.R. Emtage, Walter Funk, Y. Tom Tang, Jingsong Zhao
  • Methods and materials relating to novel prothrombinase-like polypeptides and polynucleotides
    Patent number: 7067301
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human prothrombinase-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human ovary (Hyseq clone identification number 7735656). Other aspects of the invention include vectors containing processes for producing novel human prothrombinase-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: March 13, 2003
    Date of Patent: June 27, 2006
    Assignee: Nuvelo, Inc.
    Inventors: Dana A. Haley, Bryan J. Boyle, Alice S. Ho, Matthew C. Arterburn, Nancy K. Mize
  • Methods and materials relating to fibulin like polypeptides and polynucleotides
    Publication number: 20040236090
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted fibulin-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from a cDNA library prepared from human thyroid gland mRNA (Clontech) (SEQ ID NO: 1). Other aspects of the invention include vectors containing processes for producing novel human secreted fibulin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: May 28, 2004
    Publication date: November 25, 2004
    Inventors: Shubhada Godbola, Bryan J. Boyle, Chenghua Liu, Matthew Arterburn, Radoje T. Drmanac, Y. Tom Tang
  • Methods and materials relating to semaphorin-like polynucleotides
    Patent number: 6818754
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted semaphorin-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal liver-spleen (Hyseq clone identification numbers 5688868 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted semaphorin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: June 12, 2003
    Date of Patent: November 16, 2004
    Assignee: Nuvelo. Inc.
    Inventors: Bryan J. Boyle, George Yeung, Matthew C. Arterburn, Nancy K. Mize, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • METHODS AND MATERIALS RELATING TO SEMAPHORIN-LIKE POLYNUCLEOTIDES
    Publication number: 20040220383
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted semaphorin-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal liver-spleen (Hyseq clone identification numbers 5688868 (SEQ ID NO. 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted semaphorin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: June 12, 2003
    Publication date: November 4, 2004
    Inventors: Bryan J. Boyle, George Yeung, Matthew C. Arterburn, Nancy K. Mize, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Novel nucleic acids and polypeptides
    Publication number: 20040219521
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: April 22, 2002
    Publication date: November 4, 2004
    Inventors: Y. Tom Tang, Zhiwei Wang, Gezhi Weng, Bryan J. Boyle, Radoje T. Drmanac
  • Methods and materials relating to alpha-2-macroglobulin-like polypeptides and polynucleotides
    Patent number: 6806254
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted alpha-2-macroglobulin-like polypeptides. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal brain mRNA (Clontech) (SEQ ID NO: 1) and uterus mRNA (Clontech) (SEQ ID NO: 26). Other aspects of the invention include vectors containing processes for producing novel human secreted alpha-2-macroglobulin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: January 8, 2001
    Date of Patent: October 19, 2004
    Assignee: Nuvelo, Inc.
    Inventors: Shubhada D. Godbole, Bryan J. Boyle, Nancy K. Mize, Cenhua Deng, Ryle W. Goodrich, Matthew C. Arterburn, Ping Zhou, Y. Tom Tang, Chenghua Liu, George Yeung, Radoje T. Drmanac
  • Methods and materials relating to novel growth regulatory-like polypeptides and polynucleotides
    Publication number: 20040162419
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human growth regulatory-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human thymus (Hyseq clone identification number 16372272). Other aspects of the invention include vectors containing processes for producing novel human growth regulatory-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: October 2, 2003
    Publication date: August 19, 2004
    Inventors: Bryan J. Boyle, Nancy K. Mize, Matthew C. Arterburn, John E. Ford, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Methods and materials relating to alpha-2-macroglobulin like polypeptides and polynucleotides
    Publication number: 20040152884
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted alpha-2-macroglobulin-like polypeptides. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal brain mRNA (Clontech) (SEQ ID NO: 1) and uterus mRNA (Clontech) (SEQ ID NO: 26). Other aspects of the invention include vectors containing processes for producing novel human secreted alpha-2-macroglobulin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: March 5, 2004
    Publication date: August 5, 2004
    Inventors: Shubhada D. Godbole, Bryan J. Boyle, Nancy K. Mize, Cenhua Deng, Ryle W. Goodrich, Matthew C. Arterburn, Ping Zhou, Y. Tom Tang, Chenghua Liu, George Yeung, Radoje T. Drmanac