Patents by Inventor Bryan J. Choi

Bryan J. Choi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Soft tissue repair allografts and methods for preparing same
    Patent number: 10238485
    Abstract: Allografts for soft tissue repair, including breast reconstruction and other plastic surgery procedures, are disclosed. One allograft is made from decellularized dermal tissue and constitutes a collagen matrix having substantially uniform density and porosity. Another allograft is a hybrid bilayer tissue form that is made from decellularized dermal and adipose tissues. Methods for making both allografts are also disclosed.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: March 26, 2019
    Assignee: Musculoskeletal Transplant Foundation
    Inventors: Michael Locarno, Bryan J. Choi, Manh-Dan Ngo
  • SOFT TISSUE REPAIR ALLOGRAFTS AND METHODS FOR PREPARING SAME
    Publication number: 20170281333
    Abstract: Allografts for soft tissue repair, including breast reconstruction and other plastic surgery procedures, are disclosed. One allograft is made from decellularized dermal tissue and constitutes a collagen matrix having substantially uniform density and porosity. Another allograft is a hybrid bilayer tissue form that is made from decellularized dermal and adipose tissues. Methods for making both allografts are also disclosed.
    Type: Application
    Filed: June 13, 2017
    Publication date: October 5, 2017
    Applicant: MUSCULOSKELETAL TRANSPLANT FOUNDATION
    Inventors: Michael Locarno, Bryan J. Choi, Manh-Dan Ngo
  • SOFT TISSUE REPAIR ALLOGRAFTS AND METHODS FOR PREPARING SAME
    Publication number: 20140276957
    Abstract: Allografts for soft tissue repair, including breast reconstruction and other plastic surgery procedures, are disclosed. One allograft is made from decellularized dermal tissue and constitutes a collagen matrix having substantially uniform density and porosity. Another allograft is a hybrid bilayer tissue form that is made from decellularized dermal and adipose tissues. Methods for making both allografts are also disclosed.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: MUSCULOSKELETAL TRANSPLANT FOUNDATION
    Inventors: Michael Locarno, Bryan J. Choi, Mahn-Dan Ngo
  • Human G protein-coupled receptors for metabolic-related disorders
    Patent number: 7829298
    Abstract: The present invention relates to methods of identifying whether a candidate compound is a modulator of a G protein-coupled receptor (GPCR). In preferred embodiments, the GPCR is human. In other preferred embodiments, the GPCR is coupled to Gi and lowers the level of intracellular cAMP. In other preferred embodiments, the GPCR is expressed endogenously by adipocytes. In further preferred embodiments, the GPCR inhibits intracellular lipolysis. In other further preferred embodiments, the GPCR is a nicotinic acid receptor. The present invention also relates to methods of using a modulator of said GPCR. Preferred modulator is agonist. Agonists of the invention are useful as therapeutic agents for the prevention or treatment of metabolic-related disorders, including dyslipidemia, atherosclerosis, coronary heart disease, stroke, insulin resistance, and type 2 diabetes.
    Type: Grant
    Filed: August 31, 2004
    Date of Patent: November 9, 2010
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: David J. Unett, Ruoping Chen, Jeremy G. Richman, Daniel T. Connolly, Huong T. Dang, Bryan J. Choi, James N. Leonard, Yaron Hakak, Chen W. Liaw, Dominic P. Behan, Derek T. Chalmers, Michael R. Lerner, Kevin P. Lowitz