Patents by Inventor Bryan John Smith

Bryan John Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analytical method for FAB and FAB? molecules
    Patent number: 8722353
    Abstract: A method of measuring acidic species generated by degradation of a Fab or Fab? component of a Fab-PEG or a Fab?-PEG is provided. The method involves: a) cleaving PEG and a linker from the Fab-PEG or Fab?-PEG with an enzyme; b) optionally separating the PEG and linker from the Fab or Fab? to provide isolated Fab or Fab?; and c) quantitatively analyzing acidic species associated with the cleaved Fab or Fab? and/or the cleaved PEG.
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: May 13, 2014
    Assignee: UCB Pharma, S.A.
    Inventors: Bryan John Smith, Helen Marie Kirke
  • Antibody molecules having binding specificity for human IL-13
    Patent number: 8691233
    Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of human IL-13, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.
    Type: Grant
    Filed: March 10, 2010
    Date of Patent: April 8, 2014
    Assignee: UCB Pharma S.A.
    Inventors: Neil Gozzard, Alastair David Griffiths Lawson, Daniel John Lightwood, Roger Thomas Palframan, Bryan John Smith, Kerry Louise Tyson
  • ANALYTICAL METHOD FOR FAB AND FAB' MOLECULES
    Publication number: 20130183703
    Abstract: A method of measuring acidic species generated by degradation of a Fab or Fab? component of a Fab-PEG or a Fab?-PEG comprising the steps of: a) cleaving the PEG and linker from the Fab-PEG or Fab?-PEG with an enzyme; b) optionally separating the PEG and linker generated in step a) from the Fab or Fab?, to provide a Fab or Fab?; and c) quantitatively analyzing acidic species associated with the cleaved Fab or Fab? and/or the cleaved PEG.
    Type: Application
    Filed: July 28, 2011
    Publication date: July 18, 2013
    Applicant: UCB PHARMA, S.A.
    Inventors: Bryan John Smith, Helen Marie Kirke
  • ANTIBODY MOLECULES HAVING BINDING SPECIFICITY FOR HUMAN IL-13
    Publication number: 20100260773
    Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of human IL-13, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.
    Type: Application
    Filed: March 10, 2010
    Publication date: October 14, 2010
    Inventors: Neil Gozzard, Alastair David Griffiths Lawson, Daniel John Lightwood, Roger Thomas Palframan, Bryan John Smith, Kerry Louise Tyson
  • Antibody-serum protein hybrids
    Patent number: 7105160
    Abstract: Hybrid proteins are described which comprise one or more antigen-binding antibody fragments covalently linked to one or more serum carrier proteins. The hybrid proteins can bind antigens, have a long half-life in vivo and can be used in medicine for therapy and diagnosis.
    Type: Grant
    Filed: November 10, 1999
    Date of Patent: September 12, 2006
    Assignee: Celltech Therapeutics Limited
    Inventor: Bryan John Smith