Abstract: Methods and apparatus are disclosed for interfacing with nerve fibers, such as axons. Embodiments provide multiple micro-channels, into which individual fascicles of a nerve may be placed, one fascicle per micro-channel. Each micro-channel has an associated set of micro-wire electrodes that penetrate the fascicle in the micro-channel. The micro-wire electrodes are thinner than prior art photolithographed micro-electrode arrays. Consequently, more micro-wire electrodes may interface with a single fascicle, and each micro-wire electrode interfaces with fewer axons, than in the prior art. Multiple rows of micro-channels may be stacked to construct two-dimensional arrays of micro-channels. These embodiments thereby facilitate finer motor control in prosthetic devices, and more granular sensory feedback from prosthetic devices to central nervous systems, than is achievable in the prior art.

Abstract: Systems and methods for modulating a physiological process are provided to enable precise delivery of signals to a predetermined treatment site. The systems may comprise an implantable device and an electrical lead body. The electrical lead body may comprise a plurality of transducer contacts in close proximity to an end of the electrical lead body, and a control unit positioned within the lead body in close proximity to the plurality of transducer contacts.

Abstract: A method for bonding a hermetic module to an electrode array including the steps of: providing the electrode array having a flexible substrate with a top surface and a bottom surface and including a plurality of pads in the top surface of the substrate; attaching the hermetic module to the bottom surface of the electrode array, the hermetic module having a plurality of bond-pads wherein each bond-pad is adjacent to the bottom surface of the electrode array and aligns with a respective pad; drill holes through each pad to the corresponding bond-pad; filling each hole with biocompatible conductive ink; forming a rivet on the biocompatible conductive ink over each pad; and overmolding the electrode array with a moisture barrier material.

Abstract: Methods and apparatus are disclosed for interfacing with nerve fibers, such as axons. Embodiments provide multiple micro-channels, into which individual fascicles of a nerve may be placed, one fascicle per micro-channel. Each micro-channel has an associated set of micro-wire electrodes that penetrate the fascicle in the micro-channel. The micro-wire electrodes are thinner than prior art photolithographed micro-electrode arrays. Consequently, more micro-wire electrodes may interface with a single fascicle, and each micro-wire electrode interfaces with fewer axons, than in the prior art. Multiple rows of micro-channels may be stacked to construct two-dimensional arrays of micro-channels. These embodiments thereby facilitate finer motor control in prosthetic devices, and more granular sensory feedback from prosthetic devices to central nervous systems, than is achievable in the prior art.

Abstract: An electro-encephalography system includes an internal device for implantation below a scalp and above a skull of a patient, and an external device to be worn or carried outside the patient's body. The internal device includes a first electrode for receiving neurological signals originating from the patient's brain and a second electrode for receiving artifacts originating from sources other than the patient's brain. The external device includes a processing unit for receiving data from the internal device, mitigating the effects of the artifacts, and determining a neurological state of the patient. A therapy device is included to provide a therapy to the patient based on the patient's neurological state.

Abstract: Disclosed are methods and systems for measuring and managing swelling of rechargeable batteries in situ. Some implementations involve using capacity fade or state of health of rechargeable batteries to estimate swelling of the rechargeable batteries. Some implementations provide methods and systems for measuring battery swelling based on inductive or capacitive coupling between sensors and the battery. Some implementations provide means to manage or reduce swelling of rechargeable batteries by applying adaptive charging with consideration of battery swelling.

Abstract: In various embodiments, an actuating mechanism is employed to displace a conductor disposed within a fluidic channel, thereby reconfiguring an electronic component.

Abstract: An electrical trainline junction box formed from a housing having first and second opposing sides, an identification module positioned in the housing, and first and second receptacles positioned in each of the first and second opposing sides. The first and second receptacles have a plurality of electrical contacts arranged in a predetermined geometry so that only one possible orientation and electrical connection to trainline flanges is possible. The flanges include contact pins in inserts coupled to the flanges by sleeves. The outer surface of the inserts and the inner surface of the sleeves are keyed to allow only a single orientation of the inserts relative to the sleeves. The outer surface of the sleeves is shaped to allow only a single orientation of the sleeves relative to the flanges, thus ensuring that the proper electrical connection is made when the junction box is installed.

Abstract: Systems and methods for modulating a physiological process are provided to enable precise delivery of signals to a predetermined treatment site. The systems may comprise an implantable device and an electrical lead body. The electrical lead body may comprise a plurality of transducer contacts in close proximity to an end of the electrical lead body, and a control unit positioned within the lead body in close proximity to the plurality of transducer contacts.

Abstract: In various embodiments, a probe includes at least one shank, optical components disposed within the shank for transmitting light into a sample and collecting light from the sample, and electrical components disposed within the shank for recording an electrical signal from the sample. In certain embodiments, a method includes collecting light from the sample using a first shank of the probe, recording an electrical signal from the sample using a second shank of the probe, and analyzing the collected light and the electrical signal.

Abstract: Systems and methods for modulating a physiological process are provided to enable precise delivery of signals to a predetermined treatment site. The systems may comprise an implantable device and an electrical lead body. The electrical lead body may comprise a plurality of transducer contacts in close proximity to an end of the electrical lead body, and a control unit positioned within the lead body in close proximity to the plurality of transducer contacts.

Abstract: Methods and apparatus are disclosed for interfacing with nerve fibers, such as axons. Embodiments provide multiple micro-channels, into which individual fascicles of a nerve may be placed, one fascicle per micro-channel. Each micro-channel has an associated set of micro-wire electrodes that penetrate the fascicle in the micro-channel. The micro-wire electrodes are thinner than prior art photolithographed micro-electrode arrays. Consequently, more micro-wire electrodes may interface with a single fascicle, and each micro-wire electrode interfaces with fewer axons, than in the prior art. Multiple rows of micro-channels may be stacked to construct two-dimensional arrays of micro-channels. These embodiments thereby facilitate finer motor control in prosthetic devices, and more granular sensory feedback from prosthetic devices to central nervous systems, than is achievable in the prior art.

Abstract: Systems and methods for modulating a physiological process are provided to enable precise delivery of signals to a predetermined treatment site. The systems may comprise an implantable device and an electrical lead body. The electrical lead body may comprise a plurality of transducer contacts in close proximity to an end of the electrical lead body, and a control unit positioned within the lead body in close proximity to the plurality of transducer contacts.

Abstract: Systems and methods for modulating a physiological process are provided to enable precise delivery of signals to a predetermined treatment site. The systems may comprise an implantable device and an electrical lead body. The electrical lead body may comprise a plurality of transducer contacts in close proximity to an end of the electrical lead body, and a control unit positioned within the lead body in close proximity to the plurality of transducer contacts.

Abstract: Systems and methods for modulating a physiological process are provided to enable precise delivery of signals to a predetermined treatment site. The systems may comprise an implantable device and an electrical lead body. The electrical lead body may comprise a plurality of transducer contacts in close proximity to an end of the electrical lead body, and a control unit positioned within the lead body in close proximity to the plurality of transducer contacts.

Abstract: An antenna features a ground plane having a continuous portion and one or more stubs extending therefrom.

Abstract: The present interface system includes a controller monitoring pressure on a locomotive brake pipe port, controlling pressure on a train brake pipe port in response to the pressure on a locomotive brake pipe port, providing ECP commands on an ECP trainline via a train electrical terminal in response to the pressure on the locomotive brake pipe port, and providing electrical power on the ECP trainline via an train electrical trainline terminal from the locomotive electrical trainline terminal. A transceiver is connected to the controller for wireless communication with the controller. A wireless display unit communicates via the transceiver with the controller and displays information from the controller to the operator remote from the interface system and provides inputs from the operator to the controller. The system also includes a three position change over valve. An event recorder and a GPS system may be connected to the controller.

Abstract: An antenna features a ground plane having a continuous portion and one or more stubs extending therefrom.

Abstract: In various embodiments, a probe includes at least one shank, optical components disposed within the shank for transmitting light into a sample and collecting light from the sample, and electrical components disposed within the shank for recording an electrical signal from the sample. In certain embodiments, a method includes collecting light from the sample using a first shank of the probe, recording an electrical signal from the sample using a second shank of the probe, and analyzing the collected light and the electrical signal.

Abstract: An electro-encephalography system includes an internal device for implantation below a scalp and above a skull of a patient, and an external device to be worn or carried outside the patient's body. The internal device includes a first electrode for receiving neurological signals originating from the patient's brain and a second electrode for receiving artifacts originating from sources other than the patient's brain. The external device includes a processing unit for receiving data from the internal device, mitigating the effects of the artifacts, and determining a neurological state of the patient. A therapy device is included to provide a therapy to the patient based on the patient's neurological state.