Patents by Inventor Bryan Meade

Bryan Meade has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transducible delivery of siRNA by dsRNA binding domain fusions to PTD/CPPS
    Patent number: 8273867
    Abstract: The disclosure provides fusion polypeptides and constructs useful in delivering anionically charged nucleic acid molecules including diagnostics and therapeutics to a cell or subject. The fusion constructs include a protein transduction domain and a nucleic acid binding domain, or a protein transduction domain and a nucleic acid that is coated with one or more nucleic acid binding domains sufficient to neutralize an anionic charge on the nucleic acid. Also provided are methods of treating disease and disorders such as cell proliferative disorders.
    Type: Grant
    Filed: February 9, 2007
    Date of Patent: September 25, 2012
    Assignee: The Regents of the University of California
    Inventors: Steven F. Dowdy, Jehangir S. Wadia, Bryan Meade, Akiko Eguchi
  • TRANSDUCIBLE DELIVERY OF siRNA BY dsRNA BINDING DOMAIN FUSIONS TO PTD/CPPS
    Publication number: 20090093026
    Abstract: The disclosure provides fusion polypeptides and constructs useful in delivering anionically charged nucleic acid molecules including diagnostics and therapeutics to a cell or subject. The fusion constructs include a protein transduction domain and a nucleic acid binding domain, or a protein transduction domain and a nucleic acid that is coated with one or more nucleic acid binding domains sufficient to neutralize an anionic charge on the nucleic acid. Also provided are methods of treating disease and disorders such as cell proliferative disorders.
    Type: Application
    Filed: February 9, 2007
    Publication date: April 9, 2009
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Steven F. Dowdy, Jehangir S. Wadia, Bryan Meade, Akiko Eguchi