Patents by Inventor Bryan N. Brown

Bryan N. Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Decellularization and Functionalization of Extracellular Matrix Biomaterials
    Publication number: 20240366839
    Abstract: Provided is a method of preparing an ECM material and the product of the method. The method comprises processing the ECM material with a reactive oxygen species or a reactive nitrogen species. Also provided are methods of use of the product.
    Type: Application
    Filed: July 18, 2024
    Publication date: November 7, 2024
    Inventors: Samuel LoPresti, Bryan N. Brown
  • Decellularization and functionalization of extracellular matrix biomaterials
    Patent number: 12070530
    Abstract: Provided is a method of preparing an ECM material and the product of the method. The method comprises processing the ECM material with a reactive oxygen species or a reactive nitrogen species. Also provided are methods of use of the product.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: August 27, 2024
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Samuel LoPresti, Bryan N. Brown
  • Decellularization and Functionalization of Extracellular Matrix Biomaterials
    Publication number: 20200360564
    Abstract: Provided is a method of preparing an ECM material and the product of the method. The method comprises processing the ECM material with a reactive oxygen species or a reactive nitrogen species. Also provided are methods of use of the product.
    Type: Application
    Filed: November 9, 2018
    Publication date: November 19, 2020
    Inventors: Samuel LoPresti, Bryan N. Brown
  • Decellularized Adipose Cell Growth Scaffold
    Publication number: 20180125897
    Abstract: Provided herein are methods of making a cell growth scaffold from adipose tissue, cell growth scaffolds having low lipid content and methods of using the cell growth scaffold.
    Type: Application
    Filed: November 9, 2017
    Publication date: May 10, 2018
    Inventors: Stephen Francis Badylak, Bryan N. Brown, John M. Freund, John Peter Rubin
  • Joint bioscaffolds
    Patent number: 9848987
    Abstract: Provided herein are compositions and medical devices, and in particular, biodegradable scaffolds capable of repairing and replacing cartilagenous meniscuses. Also provided herein are methods of using scaffolds for treating degenerative tissue disorders. In certain embodiments, such scaffolds can promote tissue regeneration of a temporal mandibular joint (TMJ) meniscus.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: December 26, 2017
    Assignee: University of Pittsburgh — Of the Commonwealth System of Higher Education
    Inventors: Stephen F. Badylak, Bryan N. Brown, William L. Chung
  • Decellularized adipose cell growth scaffold
    Patent number: 9814744
    Abstract: Provided herein are methods of making a cell growth scaffold from adipose tissue, cell growth scaffolds having low lipid content and methods of using the cell growth scaffold.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: November 14, 2017
    Assignee: University of Pittsburg—Of the Commonwealth System of Higher Education
    Inventors: Stephen F. Badylak, Bryan N. Brown, John M. Freund, J. Peter Rubin
  • JOINT BIOSCAFFOLDS
    Publication number: 20160143741
    Abstract: Provided herein are compositions and medical devices, and in particular, biodegradable scaffolds capable of repairing and replacing cartilagenous meniscuses. Also provided herein are methods of using scaffolds for treating degenerative tissue disorders. In certain embodiments, such scaffolds can promote tissue regeneration of a temporal mandibular joint (TMJ) meniscus.
    Type: Application
    Filed: January 28, 2016
    Publication date: May 26, 2016
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Stephen F. Badylak, Bryan N. Brown, William L. Chung
  • Joint bioscaffolds
    Patent number: 9314340
    Abstract: Provided herein are compositions and medical devices, and in particular, biodegradable scaffolds capable of repairing and replacing cartilagenous meniscuses. Also provided herein are methods of using scaffolds for treating degenerative tissue disorders. In certain embodiments, such scaffolds can promote tissue regeneration of a temporal mandibular joint (TMJ) meniscus.
    Type: Grant
    Filed: June 26, 2014
    Date of Patent: April 19, 2016
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Stephen F. Badylak, Bryan N. Brown, William L. Chung
  • Joint bioscaffolds
    Patent number: 9277999
    Abstract: Provided herein are compositions and medical devices, and in particular, biodegradable scaffolds capable of repairing and replacing cartilagenous meniscuses. Also provided herein are methods of using scaffolds for treating degenerative tissue disorders. In certain embodiments, such scaffolds can promote tissue regeneration of a temporal mandibular joint (TMJ) meniscus.
    Type: Grant
    Filed: February 26, 2010
    Date of Patent: March 8, 2016
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Stephen F. Badylak, Bryan N. Brown, William L. Chung
  • INJECTABLE CNS-DERIVED ECM FOR TISSUE RECONSTRUCTION
    Publication number: 20140356331
    Abstract: Methods useful for preparing central nervous system (CNS) derived extracellular matrix (ECM) materials, including powders and gels are provided. Also provided are CNS ECM preparations prepared according to those methods, and methods of treating a patient or mammal with CNS injury.
    Type: Application
    Filed: July 6, 2012
    Publication date: December 4, 2014
    Applicant: UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Stephen F. Badylak, Bryan N. Brown, Peter M. Crapo, Scott A. Johnson, Christopher J. Medberry
  • JOINT BIOSCAFFOLDS
    Publication number: 20140309739
    Abstract: Provided herein are compositions and medical devices, and in particular, biodegradable scaffolds capable of repairing and replacing cartilagenous meniscuses. Also provided herein are methods of using scaffolds for treating degenerative tissue disorders. In certain embodiments, such scaffolds can promote tissue regeneration of a temporal mandibular joint (TMJ) meniscus.
    Type: Application
    Filed: June 26, 2014
    Publication date: October 16, 2014
    Inventors: Stephen F. Badylak, Bryan N. Brown, William L. Chung
  • DECELLULARIZED ADIPOSE CELL GROWTH SCAFFOLD
    Publication number: 20130202563
    Abstract: Provided herein are methods of making a cell growth scaffold from adipose tissue, cell growth scaffolds having low lipid content and methods of using the cell growth scaffold.
    Type: Application
    Filed: December 20, 2010
    Publication date: August 8, 2013
    Applicant: UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Stephen F. Badylak, Bryan N. Brown, John M. Freund, J. Peter Rubin
  • JOINT BIOSCAFFOLDS
    Publication number: 20100222882
    Abstract: Provided herein are compositions and medical devices, and in particular, biodegradable scaffolds capable of repairing and replacing cartilagenous meniscuses. Also provided herein are methods of using scaffolds for treating degenerative tissue disorders. In certain embodiments, such scaffolds can promote tissue regeneration of a temporal mandibular joint (TMJ) meniscus.
    Type: Application
    Filed: February 26, 2010
    Publication date: September 2, 2010
    Inventors: Stephen F. Badylak, Bryan N. Brown, William L. Chung