Abstract: A securement assembly for supporting and stabilizing a vascular access device, such as a tunneled central venous access devices (CVAD) or a surgical drain, is provided herein. The securement assembly may comprise a base and a lid. The base may include a central post about/around which the external portion of the access device or surgical drain may be wrapped. The lid may extend from the base and may be configured to cover the external portion of the access device or surgical drain (when installed). In various embodiments, the base and the lid collectively define an annular chamber around the central post of the base.

Abstract: An apparatus for forming a trench along the bed of a body of water for burying a line lying along such bed including a support structure designed to straddle such line, means for propelling such structure straddling such line and means disposed on such structure including a pair of transversely spaced excavator devices cooperable in forming a trench along the bed of such body of water for receiving such line, each provided with a set of circumferentially spaced, pressurized fluid ejecting nozzles, rotatable about an axis.

Abstract: An apparatus for forming a trench along the bed of a body of water for burying a line lying along such bed including a support structure designed to straddle such line, means for propelling such structure straddling such line and means disposed on such structure including a pair of transversely spaced excavator devices cooperable in forming a trench along the bed of such body of water for receiving such line, each provided with a set of circumferentially spaced, pressurized fluid ejecting nozzles, rotatable about an axis.

Abstract: The present invention relates to novel benzopyran ER-? agonist compounds, pharmaceutical compositions thereof, and use of these compounds to treat a ER-? mediated disease such as nocturia, obstructive uropathy, benign prostatic hypertrophy, obesity, dementia, hypertension, incontinence, colon cancer, prostate cancer, infertility, depression, leukemia, inflammatory, bowel disease, and arthritis. Formula (I), wherein G is —O—, —S(O)—, —CF2—, —C(O)—, —CR1H— or —CR2(OH)—; R is halo, (C1-C4)alkyl or R2—(CH2)m—; R1 is F, hydroxyl, cyano, trifluoromethyl, (C1-C4)alkyl, (C2-C4)alkenyl, (C2-C4)alkynyl, (C1-C4)alkoxy, (C1-C4)alkycarbonyloxy or benzyl; R2 is trifluoromethyl or (C1-C4)alkyl; R3 is cyano, hydroxyl, (C2-C4)alkenyl, (C1-C4)alkoxy or (C1-C4)alkoxycarbonyl; n is 0, 1 or 2; and m is 0, 1 or 2; and pharmaceutically acceptable salts thereof.

Abstract: This invention relates to novel heterocycles which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), also referred to as 11CBy, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in medicines.

Abstract: The present invention relates to substituted benzopyran derivatives, stereoisomers, and pharmaceutical acceptable salts thereof and processes for the preparation of the same. The compounds of the present invention are useful as Estrogen Receptor ? agonists. Such agonists are useful for the treating Estrogen Receptor ? mediated diseases such as prostate cancer or BPH.

Abstract: The use of a natural language engine to locate software functionality in a free text document such as a requirements document is disclosed. An electronic version of a free text document is created. A natural language engine is trained to locate function points. The natural language engine performs an analysis of the electronic version of the free text document to locate function points in the electronic version of the free text document. Advantageously, the natural language engine eliminates human subjectivity from the identification of and counting of function points. Other types of functional counting methodologies can also be used in the present invention such as feature points.

Abstract: A torque indicating device comprising first and second parts connected in torque transmitting relationship,torque transmitting means connecting said first and second parts,torque sensing means, provided on said torque transmitting means and responsive to torque transmitted by said torque transmitting means, to produce a signal dependent on said transmitted torque,communicating means including a transmitter of electro-magnetic radiation receiving said signal produced by said torque sensing means, and communicating an output signal dependent on said torque to receiving means which provides an output responsive to said transmitted torque.