Patents by Inventor Bryan P. MCKIBBEN

Bryan P. MCKIBBEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic imidazole derivatives useful for the treatment of renal diseases, cardiovascular diseases and fibrotic diseases
    Patent number: 10858342
    Abstract: The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5 and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: December 8, 2020
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Michael Balestra, Jennifer Burke, Zhidong Chen, Derek Cogan, John Lord, Daniel Richard Marshall, Bryan P. McKibben, Kenneth M. Meyers, Yunlong Zhang
  • BICYCLIC IMIDAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF RENAL DISEASES, CARDIOVASCULAR DISEASES AND FIBROTIC DISEASES
    Publication number: 20200109131
    Abstract: The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5 and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Application
    Filed: June 21, 2017
    Publication date: April 9, 2020
    Inventors: Michael BALESTRA, Jennifer BURKE, Zhidong CHEN, Derek COGAN, John LORD, Daniel Richard MARSHALL, Bryan P. MCKIBBEN, Kenneth M. MEYERS, Yunlong ZHANG
  • Aldosterone synthase inhibitors
    Patent number: 9334285
    Abstract: The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein Cy, R1 and R2 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Grant
    Filed: July 23, 2015
    Date of Patent: May 10, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Jennifer Burke, Matthew A. Cerny, Derek Cogan, Kosea S. Frederick, John Lord, Daniel Richard Marshall, Bryan P. McKibben, Simon Suprenant, Maolin Yu, Yunlong Zhang, Lee Fader
  • ALDOSTERONE SYNTHASE INHIBITORS
    Publication number: 20160024105
    Abstract: The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein Cy, R1 and R2 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Application
    Filed: July 23, 2015
    Publication date: January 28, 2016
    Inventors: Jennifer BURKE, Matthew A. CERNY, Derek COGAN, Kosea S. FREDERICK, John LORD, Daniel Richard MARSHALL, Bryan P. MCKIBBEN, Simon SURPRENANT, Maolin YU, Yunlong ZHANG, Lee FADER