Abstract: Methods and systems are provided for small molecule analyte detection using digital signals, key encryption, and communications protocols. The methods provide detection of a large numbers of proteins, peptides, RNA molecules, and DNA molecules in a single optical or electrical detection assay within a large dynamic range.

Abstract: A method of determining the best position for an inner member relative to an outer member within a rotary machine requires the inner and outer members to be rotated relative to one another. The spacing between the inner and outer members at at least one location along the length of the rotary machine is detected generally continuously over at least one complete revolution. The detected spacing is then processed to determine the best position for the inner member relative to the outer member. An apparatus for carrying out the method is also disclosed.