Patents by Inventor Bryan Q. Spring

Bryan Q. Spring has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating and imaging tumor micrometastases using photoactive immunoconjugates
    Patent number: 11547300
    Abstract: Methods for evaluating micrometastases in a tissue region of a subject are described. The methods include administering to the subject a detectably effective amount of a tumor-targeted photoactivatable immunoconjugate; allowing a sufficient amount of time for the tumor-targeted photoactivatable immunoconjugate to enter micrometastases in the tissue region; illuminating the tumor-targeted photoactivatable immunoconjugate; obtaining an image of the tissue region of the subject using a fluorescent imaging device, and evaluating the micrometastases in the tissue region by conducting algorithmic analysis of the image. Methods of treating micrometastases in a tissue region of a subject are also described.
    Type: Grant
    Filed: February 2, 2015
    Date of Patent: January 10, 2023
    Assignee: The General Hospital Corporation
    Inventors: Tayyaba Hasan, Bryan Q. Spring, Akilan Palanisami
  • METHODS OF TREATING AND IMAGING TUMOR MICROMETASTASES USING PHOTOACTIVE IMMUNOCONJUGATES
    Publication number: 20160345834
    Abstract: Methods for evaluating micrometastases in a tissue region of a subject are described. The methods include administering to the subject a detectably effective amount of a tumor-targeted photoactivatable immunoconjugate; allowing a sufficient amount of time for the tumor-targeted photoactivatable immunoconjugate to enter micrometastases in the tissue region; illuminating the tumor-targeted photoactivatable immunoconjugate; obtaining an image of the tissue region of the subject using a fluorescent imaging device, and evaluating the micrometastases in the tissue region by conducting algorithmic analysis of the image. Methods of treating micrometastases in a tissue region of a subject are also described.
    Type: Application
    Filed: February 2, 2015
    Publication date: December 1, 2016
    Inventors: Tayyaba Hasan, Bryan Q. Spring, Akilan Palanasami