Patents by Inventor Bryan Wang

Bryan Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250145934
    Abstract: The present disclosure relates to improved biomanufacturing systems and methods with an ability to effectively control process variability to consistently generate high-quality cell-based therapies. In particular, disclosed herein is a using model-based control for determining process parameters in a bioreactor in real time. Additionally disclosed herein is a system for generating an AI digital twin model for a commercial-scale bioreactor.
    Type: Application
    Filed: February 7, 2023
    Publication date: May 8, 2025
    Inventors: Stephen BALAKIRSKY, Annie BOWLES-WELCH, Walker Thomas BYRNES, Bharat KANWAR, Zhaonan LIU, Krishnendu ROY, Bryan WANG, Carolyn YEAGO, Chuck ZHANG
  • Publication number: 20250136915
    Abstract: An automated sampling platform includes a gantry-style 2D or 3D actuator equipped with a syringe pump end effector configured to extract samples from a rubber septum placed in-line within a tubing-based system and to deposit the extracted samples into sealed cryovials for storage. This device can be employed for use in cell culture bioreactors, such as the Terumo Quantum, which include a waste line.
    Type: Application
    Filed: February 7, 2023
    Publication date: May 1, 2025
    Inventors: Walker Thomas BYRNES, Stephen BALAKIRSKY, Annie BOWLES-WELCH, Bharat KANWAR, Krishnendu ROY, Bryan WANG, Carolyn YEAGO
  • Publication number: 20250117119
    Abstract: Systems and methods for language augmented video editing are disclosed. A method includes presenting a video editing assistant (e.g., via a communicatively coupled display and/or speaker). The method includes, in response to receiving a request from a user to create adaptive video content that satisfies a set of characteristics identified based on the request i) analyzing, using a first machine-learning model, existing video content to identify portions of the existing video content that satisfy the set of characteristics and ii) for each portion of the existing video content that satisfies the set of characteristics, create adaptive video content using a respective portion of the existing video content that satisfies the set of characteristics. The method includes generating, using a second machine-learning model, descriptions of the adaptive video content and presenting the adaptive video content and the descriptions of the adaptive video content.
    Type: Application
    Filed: October 8, 2024
    Publication date: April 10, 2025
    Inventors: Bryan Wang, Rajinder Sodhi, Yan Xu, Zhaoyang Lv, Yuliang Li
  • Publication number: 20240211171
    Abstract: A request to perform a memory operation addressed to a first address corresponding to a first logical unit of logical units of a memory is received. Address mask data that corresponds to the logical units is identified. Multiple transformed addresses are determined using the first address and the address mask data. The transformed addresses can include a target address corresponding to the first logical unit and additional addresses corresponding to other logical units. The memory operation is performed at the target address corresponding to the first logical unit and dummy memory operations are performed at the additional addresses corresponding to the additional logical units.
    Type: Application
    Filed: December 6, 2023
    Publication date: June 27, 2024
    Inventors: Winthrop John Wu, Bryan Wang, Marufa Kaniz, Guilherme Ozari de Almeida, Scott C. Best
  • Patent number: 11710332
    Abstract: Methods, systems, and computer storage media are provided for data extraction. A target document representation may be generated based on modified text of a target electronic document. A measure of similarity may be determined between the target document representation and a reference document representation, which may be based on modified text of a reference electronic document. Based on the measure of similarity, the reference document representation may be selected. An extraction model associated with the selected reference document representation can then be used to extract data from the target document.
    Type: Grant
    Filed: December 6, 2021
    Date of Patent: July 25, 2023
    Assignee: BILL.COM, LLC
    Inventors: Changlin Zhang, Bryan Wang, Akshay Ukey, Sangam Singh
  • Publication number: 20220165078
    Abstract: Methods, systems, and computer storage media are provided for data extraction. A target document representation may be generated based on modified text of a target electronic document. A measure of similarity may be determined between the target document representation and a reference document representation, which may be based on modified text of a reference electronic document. Based on the measure of similarity, the reference document representation may be selected. An extraction model associated with the selected reference document representation can then be used to extract data from the target document.
    Type: Application
    Filed: December 6, 2021
    Publication date: May 26, 2022
    Inventors: Changlin Zhang, Bryan Wang, Akshay Ukey, Sangam Singh
  • Publication number: 20220127681
    Abstract: Disclosed is a method for identifying cell-type specific EV markers comprising culturing induced pluripotent stem cells (iPSCs) to provide a culture of a first differentiated cell type; isolating extracellular vesicles (EV)s from the culture of the differentiated cell type; generating a microscopic RNA (miRNA) expression profile for the differentiated cell type by next-generation sequencing; and identifying specific miRNA markers associated with the differentiated cells.
    Type: Application
    Filed: February 27, 2020
    Publication date: April 28, 2022
    Inventors: Gordana VUNJAK-NOVAKOVIC, Bohao LIU, Bryan WANG
  • Patent number: 11195008
    Abstract: Methods, systems, and computer storage media are provided for data extraction. A target document representation may be generated based on modified text of a target electronic document. A measure of similarity may be determined between the target document representation and a reference document representation, which may be based on modified text of a reference electronic document. Based on the measure of similarity, the reference document representation may be selected. An extraction model associated with the selected reference document representation can then be used to extract data from the target document.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: December 7, 2021
    Inventors: Changlin Zhang, Bryan Wang, Akshay Ukey, Sangam Singh
  • Patent number: 11143189
    Abstract: A novel integrated modular, multi-stage motor-pump/compressor device (10) is disclosed herein. In one example, the device (10) includes an outer housing (12) an electric motor stator (25) positioned within the outer housing (12) and a rotatable integrated motor/pump rotor (18) positioned within the electric motor stator (25). The rotatable integrated motor/pump rotor (18) comprises at least one electromagnet driver device (42, 33, 37) that is adapted to be electromagnetically coupled with the electric motor stator (25) and at least one impeller (28), where an inner surface (34A) of the rotatable integrated motor/pump rotor (18) and the impeller (28) define a primary process fluid flow path (36) within the rotatable integrated motor/pump rotor (18).
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: October 12, 2021
    Assignee: FMC Technologies, Inc.
    Inventors: Costin Ifrim, Bradley Dean Beitler, Bryan Wang Lam, Brian Scott Dejarnett
  • Publication number: 20210133498
    Abstract: Methods, systems, and computer storage media are provided for data extraction. A target document representation may be generated based on modified text of a target electronic document. A measure of similarity may be determined between the target document representation and a reference document representation, which may be based on modified text of a reference electronic document. Based on the measure of similarity, the reference document representation may be selected. An extraction model associated with the selected reference document representation can then be used to extract data from the target document.
    Type: Application
    Filed: October 30, 2019
    Publication date: May 6, 2021
    Inventors: Changlin Zhang, Bryan Wang, Akshay Ukey, Sangam Singh
  • Publication number: 20200370016
    Abstract: Provided herein are methods of generating a population of enucleated erythroid cells.
    Type: Application
    Filed: May 22, 2020
    Publication date: November 26, 2020
    Applicant: Rubius Therapeutics, Inc.
    Inventors: Jonathan Lipsitz, Brian Joseph Pereira, Bryan Wang, Alan Gilbert
  • Publication number: 20190032667
    Abstract: A novel integrated modular, multi-stage motor-pump/compressor device (10) is disclosed herein. In one example, the device (10) includes an outer housing (12) an electric motor stator (25) positioned within the outer housing (12) and a rotatable integrated motor/pump rotor (18) positioned within the electric motor stator (25). The rotatable integrated motor/pump rotor (18) comprises at least one electromagnet driver device (42, 33, 37) that is adapted to be electromagnetically coupled with the electric motor stator (25) and at least one impeller (28), where an inner surface (34A) of the rotatable integrated motor/pump rotor (18) and the impeller (28) define a primary process fluid flow path (36) within the rotatable integrated motor/pump rotor (18).
    Type: Application
    Filed: January 22, 2016
    Publication date: January 31, 2019
    Inventors: Costin Ifrim, Bradley Dean Beitler, Bryan Wang Lam, Brian Scott Dejarnett
  • Patent number: 8728982
    Abstract: The invention relates to a compositions and methods for generating and using pIX phage display libraries for producing non-antibody peptide or protein proteins or peptides using engineered hybrid phage vectors derived from pIX of M 13 phage
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: May 20, 2014
    Assignee: Centoco Ortho Biotech Inc.
    Inventors: Bryan Wang, Linus Hyun, Karyn O'Neil
  • Publication number: 20100249377
    Abstract: The invention relates to a compositions and methods for generating and using pIX phage display libraries for producing non-antibody peptide or protein proteins or peptides using engineered hybrid phage vectors derived from pIX of M 13 phage
    Type: Application
    Filed: November 21, 2008
    Publication date: September 30, 2010
    Inventors: Bryan Wang, Karyn O'Neil
  • Publication number: 20100098681
    Abstract: Polypeptides comprising EGFR extracellular domains I-III capable of forming dimeric EGF-binding proteins are provided. The dimeric construct of the invention is useful in applications where high affinity EGF binding is desired and can be used to select agents capable of binding to native EGFR in the presence of EGF.
    Type: Application
    Filed: December 20, 2007
    Publication date: April 22, 2010
    Inventors: Bryan Wang, Frank Shi, Juliane Mills
  • Patent number: 7429963
    Abstract: An image processing device includes a frame buffer, a first display engine, a clock signal generator, a spread spectrum clock generator, a first-in-first-out (FIFO) buffer and a reset signal generator. The FIFO buffer receives and stores the pixel digital data from the first display engine according to a data writing index controlled by a working clock signal from the clock signal generator and outputs the pixel digital data to the planar display according to a data reading index controlled by a spread spectrum clock signal from the spread spectrum clock generator. The reset signal generator receives and checks the pixel digital data and generates a reset signal to the FIFO buffer to reset the data writing index and the data reading index when one of the pixel digital data to be inputted into the FIFO buffer is consistent with a preset condition.
    Type: Grant
    Filed: May 25, 2005
    Date of Patent: September 30, 2008
    Assignee: Via Technologies, Inc.
    Inventors: Pingo Chia, Yi-Chieh Huang, Bryan Wang
  • Publication number: 20050264553
    Abstract: An image processing device includes a frame buffer, a first display engine, a clock signal generator, a spread spectrum clock generator, a first-in-first-out (FIFO) buffer and a reset signal generator. The FIFO buffer receives and stores the pixel digital data from the first display engine according to a data writing index controlled by a working clock signal from the clock signal generator and outputs the pixel digital data to the planar display according to a data reading index controlled by a spread spectrum clock signal from the spread spectrum clock generator. The reset signal generator receives and checks the pixel digital data and generates a reset signal to the FIFO buffer to reset the data writing index and the data reading index when one of the pixel digital data to be inputted into the FIFO buffer is consistent with a preset condition.
    Type: Application
    Filed: May 25, 2005
    Publication date: December 1, 2005
    Inventors: Pingo Chia, Yi-Chieh Huang, Bryan Wang
  • Publication number: 20040265917
    Abstract: The present invention provides a method of assessing the ability of a compound (the “test compound”) which is an inhibitor of a biological target to inhibit the biological target in a biological compartment of interest when administered to a subject in vivo.
    Type: Application
    Filed: April 7, 2004
    Publication date: December 30, 2004
    Inventors: Dennis Benjamin, Charles Thompson, Bryan Wang, James Wakefield, Malcolm L. Gefter, Christopher C. Arico-Muendel